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Genomes as documents of evolutionary history

Vendredi 17 mai 2013 de 14h à 15h30, salle 12,à l'IBC, 95 rue de la Galéra, 34095 Montpellier cedex 5

Présentation:Eric Tannier, INRIA Rhône-Alpes, LBBE, Université de Lyon 1                     
http://lbbe.univ-lyon1.fr/-Tannier-Eric-.html?lang=en

Titre: Genomes as documents of evolutionary historyRésumé :In 1965, Zuckerkandl and Pauling proposed to use "Molecules as documents of evolutionary history". DNA indeed contains the most abundant historical archive of the past billions years of life on earth. I will present how this research programme is implemented today, with thousands of whole genome sequences. We have to integrate in a single model evolutionary events that occur at very different scales on genomes, from base substitutions to genome rearrangements, through gene duplications and deletions. We have to distinguish different types of transmission of genetic information: vertical, from parents, and horizontal, from neighbors. While horizontal inheritance may at first be seen as a hurdle for life historiography because it mixes genealogical and ecological relationships, we will see it can be turned into a precious support, recording and dating diversification events which had left no other fossil traces.

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Dernière mise à jour le 24/06/2013