Mathematical and computational tools and concepts form an essential basis for modern evolutionary studies. The rise of sound statistical and combinatorial approaches in evolutionary and genome biology has seen considerable improvements of the original ad hoc methods and the ability of the new methods and algorithms to handle ever-larger data sets. Such advances involve increasingly sophisticated mathematical treatment of the problems at hand and the reliance on faster algorithms and computers in order to answer important biological questions. This year a special focus will be given to the applications of mathematical and computational evolutionary biology to health, for example with regard to human and cancer genomics, genetic diseases and virus epidemics. General concepts, models, methods and algorithms will also be presented and discussed, just as during the previous conference editions. The plan is to change the focus from year to year with emphasis on topical application domains. To present the recent advances in the field and discuss open questions and problems, the meeting will bring together researchers originating from various disciplines: mathematics, computer science, phylogenetics and population genetics. Ten keynote speakers, two each morning, will introduce a field of research and discuss their own work in this field. Afternoon will be for short presentations and posters, with plenty of time for discussions. We will stop early every day, thus leaving time for hiking and visits. The number of attendees will be limited (~60), so as to favor exchanges.

The meeting will take place at Hameau de l'Etoile, in the Montpellier region (France). The dates are May 27-31. The first talk will begin at 11:00 on Monday the 27th and the conference will end at 16:00 on Friday the 31st. We will organize a bus transfer from central Montpellier on Monday at 09:00 and a return on Friday afternoon (see the meeting point). Conference fees including accommodation (4 nights, 27 to 31), meals, coffee breaks, buses, etc., will range from ~350 € to ~500 € depending on the room type (see Hameau de L'Etoile). PhDs and postdocs will benefit of the cheapest rooms.

• Sebastian Bonhoeffer (ETH Zürich, CH).
  The paradox of heritability of HIV viral load?
• Bastien Boussau (University of California, Berkeley, US).
  Genome-scale phylogenomics.
• Alexei Drummond (University of Auckland, NZ).
  Bayesian molecular epidemiology.
• Ian Holmes (University of California, Berkeley, US).
  Phylogenetics grammars and heterogeneous space-time models.
• Steven Kelk (Maastricht University, NL).
  Recent advances in rooted phylogenetic networks: the long road to explicit hypothesis generation.
• Darren Martin (University of Cape Town, SA).
  Factors influencing recombination in viruses.
• Erick Matsen (Fred Hutchinson Cancer Research Center, Seattle, US).
  Phylogenetics and the human microbiome.
• Tanja Stadler (ETH Zürich, CH).
  Phylogenetics in action - merging epidemiology and evolutionary biology.
• Niko Beerenwinkel (ETH Zürich, CH).
  Cancer as an evolutionary process.
• Gil McVean (University of Oxford, UK).
  Dissecting the genetic contribution to human disease.

• Pre-registration deadline: January 31
• Notification to applicants: end of February
• Final list of attendees: March 15

• Olivier Gascuel (Chair).
• Samuel Alizon (CNRS - MIVEGEC).
• Caroline Benoist (CNRS - LIRMM).
• Emmanuel Cornillot (Université Montpellier I - LBCM).
• Raphaël Leblois (INRA - CBGP).
• Vincent Lefort (CNRS - LIRMM).
• Jean-Michel Marin (Université Montpellier II - I3M).
• Fabio Pardi (CNRS - LIRMM).
• Pierre Pudlo (Université Montpellier II - I3M).
• Vincent Ranwez (Montpellier SupAgro - DAVEM).
• Céline Scornavacca (CNRS - ISEM).

• Mathematics of Evolution and Phylogeny (2003 and 2005).
• Mathematics and Informatics in Evolution and Phylogeny (2008).
• Mathematical and Computational Evolutionary Biology (2012).