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Integrated Project - Blood complex object

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 The quantity and the heterogeneity of the elements that compose blood make it a “complex” fluid. The mechanical and electrical properties of the membrane and core of the blood cells are still partly known today although they are most probably biomarkers of certain pathologies. The way in which the particles interact between themselves or with foreign bodies is still largely unknown today but affects the apparent viscosity of the fluid. Because it is a biofluid, blood must be operated with precaution. The red cells subjected to too strong stresses can be destroyed (hemolysis). Contrary, if blood is not sufficiently loaded, platelets may be activated causing the appearance of clots (thrombosis). Being able to model the chemical-mechanical phenomena associated with normal and pathological blood is a necessary step for addressing many challenges of industrial (e.g.: optimization of medical devices) and/or medical (e.g.: development of innovating therapeutic strategies) interest.

 

Test of permeability on flowdiverter cerebral stents

 Sickle red blood cell aggregation beyond a triangular pillar (Edge lenght 60 microns)
Biological Physics. Université Montpellier II - Sciences et Techniques du Languedoc, 2011