>YER021W RPN3 SGDID:S000000823, Chr V from 196947-198518, Verified
           ORF, "Essential, non-ATPase regulatory subunit of the
           26S proteasome lid, similar to the p58 subunit of the
           human 26S proteasome; temperature-sensitive alleles
           cause metaphase arrest, suggesting a role for the
           proteasome in cell cycle control"
          Length = 523

 Score =  227 bits (578), Expect = 9e-64
 Identities = 145/454 (31%), Positives = 236/454 (51%), Gaps = 18/454 (3%)

Query: 31  VNNLLTSVNYINNAIVHKDNRHMLRMLKYIKNIR-LSIKNDKNMSMPI-IIYLIKRIFKE 88
           V  LL  +N I+   +  D R++ R LK + ++R   + N + +   + ++Y     FK+
Sbjct: 31  VQELLKVLNEISKTTLTLDPRYIWRSLKDLSSLRNQELLNAETLCFTVNVLYPDSSSFKK 90

Query: 89  NYPIYNILNKYMNIYEEGLYKEI--SDFYNIN-EKTYMNCLPXXXXXXXXXXXXXXXDEK 145
           N   +   N   ++      +    + FY++N EK  +                   D K
Sbjct: 91  NLLKFITSNHKSSVPGSAELRNSYPASFYSVNTEKKTIEVTAEINCFMHLLVQLFLWDSK 150

Query: 146 CYDEGMELS--TXXXXXXXXXXXXSLDYINAKVYFYYSWIHELGGKLSQ----------V 193
             ++ +E +               SL+ INAK++FY    HE   + S+          +
Sbjct: 151 ELEQLVEFNRKVVIPNLLCYYNLRSLNLINAKLWFYIYLSHETLARSSEEINSDNQNIIL 210

Query: 194 RQKLLFIYRNACLHRDIMTQTVVVNLILRDYIKHNLYDLAVRFISKTSFPENLSSNAQYA 253
           R  ++   + A L  D  T+ +++NLILRD++ +   D A  FISK  +P    S++  A
Sbjct: 211 RSTMMKFLKIASLKHDNETKAMLINLILRDFLNNGEVDSASDFISKLEYPHTDVSSSLEA 270

Query: 254 RYLYYIGKILAVQLDYSEAHRKITQALRKAPQHTQSAKGFKLAATKMEIVVELLMGDIPD 313
           RY +Y+ KI A+QLDYS A+  I  A+RKAP H   + GF   + K+   ++LLMGDIP+
Sbjct: 271 RYFFYLSKINAIQLDYSTANEYIIAAIRKAP-HNSKSLGFLQQSNKLHCCIQLLMGDIPE 329

Query: 314 RSIFSNKIMYKKLIPYKHVVSAVRNGDINKFAQVMNNYTDLFIHDGVYLLIKRIHHNVIK 373
            S F    M K L+PY H+  AV+ GD+ KF   +  Y  L + D  Y L  R+  NVIK
Sbjct: 330 LSFFHQSNMQKSLLPYYHLTKAVKLGDLKKFTSTITKYKQLLLKDDTYQLCVRLRSNVIK 389

Query: 374 TALRIINLSYSRISINDIGKKIGIESSLDVVGITAKAIHDGVIEGTIDYENQYVESKSNS 433
           T +RII+L+Y +IS+ DI  K+ ++S   V  + ++AI DGVIE  I++E+ ++E+    
Sbjct: 390 TGIRIISLTYKKISLRDICLKLNLDSEQTVEYMVSRAIRDGVIEAKINHEDGFIETTELL 449

Query: 434 DIYITGDPMKTFHKRIAFCLQLYSDAIKAMQYPD 467
           +IY + DP + F +RI F  QL+ + + +M+YP+
Sbjct: 450 NIYDSEDPQQVFDERIKFANQLHDEYLVSMRYPE 483

Lambda     K      H
   0.322    0.137    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 607
Number of extensions: 24
Number of successful extensions: 4
Number of sequences better than 10.0: 1
Number of HSP's gapped: 2
Number of HSP's successfully gapped: 2
Length of query: 503
Length of database: 523
Length adjustment: 35
Effective length of query: 468
Effective length of database: 488
Effective search space:   228384
Effective search space used:   228384
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 26 (14.9 bits)
S2: 26 (14.6 bits)