>YOL021C DIS3 SGDID:S000005381, Chr XV from 285427-282422, reverse
            complement, Verified ORF, "Nucleolar exosome component,
            involved in rRNA processing and RNA degradation, binds
            Gsp1p/Ran and enhances the GEF activity of Srm1p,
            implicated in mitotic control, homologous to the E. coli
            RNase R of the RNase II family"
          Length = 1001

 Score =  305 bits (781), Expect = 1e-86
 Identities = 217/613 (35%), Positives = 317/613 (51%), Gaps = 42/613 (6%)

Query: 420  NKNNDIVQKDMINLYEKKMNITY--DKQXXXXXXXXXXXRHISEKKKLYGKVVGIISRCR 477
            N N DI   D  +  E   N T   DKQ           +  S+K +   KVV I  R  
Sbjct: 342  NDNPDIEAGDDDDNNESSSNTTVISDKQRRLLAKDAMIAQR-SKKIQPTAKVVYIQRRSW 400

Query: 478  KEYGGIIKEYSNNLNNIKKKLMFFKAFNNKIPYIMIKAQLEDELRNKRVIVTIDNWDIYS 537
            ++Y G +   S +  +   + +F    +  +P + I+ +   EL +KR++++ID+W    
Sbjct: 401  RQYVGQLAPSSVDPQSSSTQNVFVILMDKCLPKVRIRTRRAAELLDKRIVISIDSWPTTH 460

Query: 538  RNPLGRCISVLGNCDDIETETKLIYNEYNISTREFSENVYKCLPP--NNWVIP------- 588
            + PLG  +  LG  +  + ET+ +  E+++  R FS+ V +CLP   ++W  P       
Sbjct: 461  KYPLGHFVRDLGTIESAQAETEALLLEHDVEYRPFSKKVLECLPAEGHDWKAPTKLDDPE 520

Query: 589  ----DEEYEKRNDFRNVLTFSIDPPGCQDIDDALSVEFLQQDGNIEKNYIYRIGVHIADV 644
                D    KR D R+ L  SIDPPGC DIDDAL  + L  +GN E      +GVHIADV
Sbjct: 521  AVSKDPLLTKRKDLRDKLICSIDPPGCVDIDDALHAKKLP-NGNWE------VGVHIADV 573

Query: 645  SYFVKQNSPIDLEASKRCTTVYLINQRVDMLPKLLTTNLCSLVEGEERLTYSCIFCFNKD 704
            ++FVK  + +D E + R T+VYL+++R+DMLP LL T+LCSL    +R  +S I+  +  
Sbjct: 574  THFVKPGTALDAEGAARGTSVYLVDKRIDMLPMLLGTDLCSLKPYVDRFAFSVIWELDDS 633

Query: 705  FDIIDISVKKCIIKSNKSFSYEQAQNVIDDKNDQSDTAKSLRLLNKIAKHLKQKWSNDGA 764
             +I++++  K +I+S ++FSYEQAQ  IDDK    +    +R L K++  LKQK    GA
Sbjct: 634  ANIVNVNFMKSVIRSREAFSYEQAQLRIDDKTQNDELTMGMRALLKLSVKLKQKRLEAGA 693

Query: 765  LELRG-NTEVLFEFEANDFSKAKNLKPYVCYETNKLIEAFMLLANRSVARIIFQNFKAAS 823
            L L     +V  + E +D ++ +  K      TN L+E FMLLAN SVAR I+  F   +
Sbjct: 694  LNLASPEVKVHMDSETSDPNEVEIKK---LLATNSLVEEFMLLANISVARKIYDAFPQTA 750

Query: 824  VLRRHPPPKHEYLKELNDYLKTIQVFDFKYNTSKDLSHXXXXXXXXXXXXXXXXXXVMVT 883
            +LRRH  P     + LN+ L T +       +SK L+                   +M T
Sbjct: 751  MLRRHAAPPSTNFEILNEMLNTRKNMSISLESSKALADSLDRCVDPEDPYFNTLVRIMST 810

Query: 884  KCMNEA-VFISGYNVHNNDMLRHYGLAADIYTFFTSPIRRYADIMVHRILNHIYQIEEL- 941
            +CM  A  F SG   ++    RHYGLA DIYT FTSPIRRY D++ HR L      E L 
Sbjct: 811  RCMMAAQYFYSG--AYSYPDFRHYGLAVDIYTHFTSPIRRYCDVVAHRQLAGAIGYEPLS 868

Query: 942  ----DKKYLDIIYLNKQVALLNDKYRNARFASRASVDFFSYLYIKKIGNQITNAVITNLK 997
                DK  +D+I  N     +N K+RNA+FA RAS++++    ++   +  T  VI    
Sbjct: 869  LTHRDKNKMDMICRN-----INRKHRNAQFAGRASIEYYVGQVMRNNESTETGYVIKVF- 922

Query: 998  KNEGICYLKRKDG 1010
             N GI  L  K G
Sbjct: 923  -NNGIVVLVPKFG 934

 Score = 58.9 bits (141), Expect = 2e-12
 Identities = 78/358 (21%), Positives = 143/358 (39%), Gaps = 80/358 (22%)

Query: 16  QKYFYKLNANNRINKIVREVYLRNDISCGXXXXXXXXXXXXXXXDGE------------- 62
           QK F + + N    KIVRE YLR+DI C                  E             
Sbjct: 21  QKVFVR-SRNGGATKIVREHYLRSDIPCLSRSCTKCPQIVVPDAQNELPKFILSDSPLEL 79

Query: 63  -----RSILILDLNTLIKYMDFLYD--CDIDNILIPLSIYDYIKSFNKILYKKLRNLCYD 115
                +  ++LD N +++ +D L +  C  D +++P  + D +++ +  +Y +LR LC D
Sbjct: 80  SAPIGKHYVVLDTNVVLQAIDLLENPNCFFD-VIVPQIVLDEVRNKSYPVYTRLRTLCRD 138

Query: 116 VDXXXXXXXXXXXXXFNHNKRFCVFVNTFCKFTYVEDNKDDTNGFNKELQEIIKIVIWLK 175
            D                +KRF VF N F + T+VE   ++T   ++  + I K   W  
Sbjct: 139 SD---------------DHKRFIVFHNEFSEHTFVERLPNETIN-DRNDRAIRKTCQWYS 182

Query: 176 HHNN--KLNIKVISNNKLLQEDC---YNNDIPCSTLFEYVNELMXXXXXXXXXXXXXXFN 230
            H     +N+ +++N++L +E       ++I   +L +Y+  L                N
Sbjct: 183 EHLKPYDINVVLVTNDRLNREAATKEVESNIITKSLVQYIELLP---------------N 227

Query: 231 MDTLKMYFEEDILNEHNDSKADHTESTCDQKTYHTXXXXXXXXXXXXKRPLYEPHLSKSD 290
            D ++     D + + +    D    T    T+                 LY+ ++    
Sbjct: 228 ADDIR-----DSIPQMDSFDKDLERDTFSDFTFPEYYSTARVMGGLKNGVLYQGNI---- 278

Query: 291 MIQKLRENKIIKGVFSVICVNKLALVKFSDVDEIVIRGTKYMNRAIHNDVVAVEIIDE 348
              ++ E   ++G         ++L +FS    ++I G K +NRA + D V VE++ +
Sbjct: 279 ---QISEYNFLEG--------SVSLPRFS--KPVLIVGQKNLNRAFNGDQVIVELLPQ 323

Lambda     K      H
   0.321    0.138    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 2102
Number of extensions: 102
Number of successful extensions: 10
Number of sequences better than 10.0: 1
Number of HSP's gapped: 5
Number of HSP's successfully gapped: 5
Length of query: 1062
Length of database: 1001
Length adjustment: 45
Effective length of query: 1017
Effective length of database: 956
Effective search space:   972252
Effective search space used:   972252
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 32 (17.7 bits)
S2: 32 (16.9 bits)