>YCL043C PDI1 SGDID:S000000548, Chr III from 50221-48653, reverse
           complement, Verified ORF, "Protein disulfide isomerase,
           multifunctional protein resident in the endoplasmic
           reticulum lumen, essential for the formation of
           disulfide bonds in secretory and cell-surface proteins,
           unscrambles non-native disulfide bonds"
          Length = 522

 Score =  177 bits (450), Expect = 6e-49
 Identities = 141/475 (29%), Positives = 227/475 (47%), Gaps = 42/475 (8%)

Query: 33  VTDIHDGELDKFITKNDIVLVMFYAPWCGHCKRLIPEYNEAANMLNEKKSEIKLVSIDAT 92
           V  +     +++I  +D+VL  F+APWCGHCK + PEY +AA  L EK   I L  ID T
Sbjct: 34  VVKLATDSFNEYIQSHDLVLAEFFAPWCGHCKNMAPEYVKAAETLVEK--NITLAQIDCT 91

Query: 93  SENALAQEYGITGYPTLILFNK---KNKINYGGGRTAQSIVDWLLQMTGPVFSHVEGNIE 149
               L  E+ I G+P+L +F      N I+Y G RTA++IV ++++ + P  + V  ++ 
Sbjct: 92  ENQDLCMEHNIPGFPSLKIFKNSDVNNSIDYEGPRTAEAIVQFMIKQSQPAVA-VVADLP 150

Query: 150 DVLKEKKINVAFYLEYTSEDNDLYKKFNEVGDKNREIAKYFVKKN-DKHNKLFCF---RT 205
             L  +       ++    D D    F  + +K+     +   +N D   KL  +     
Sbjct: 151 AYLANETFVTPVIVQSGKIDADFNATFYSMANKHFNDYDFVSAENADDDFKLSIYLPSAM 210

Query: 206 DE------KKVEYDEKTPLEEFVTSESFPLFGEINTENYRFYAESPKELVWVCATYEQYN 259
           DE      KK +  +    E+++  E+ P FGEI+   +  Y ES   L ++   Y    
Sbjct: 211 DEPVVYNGKKADIADADVFEKWLQVEALPYFGEIDGSVFAQYVESGLPLGYL--FYNDEE 268

Query: 260 EIKEHVRLAAQELRKKT----HFVLLNIPEYAEHAKASLGLTEFPGLAF--QSNEGRYLL 313
           E++E+  L   EL KK     +FV ++  ++  HA       +FP  A    + + +Y L
Sbjct: 269 ELEEYKPLFT-ELAKKNRGLMNFVSIDARKFGRHAGNLNMKEQFPLFAIHDMTEDLKYGL 327

Query: 314 KNPKES---------LLNHNAIINFFKDVEAGKIEKSLKSEPIPEDDKNAPVKIVVGNSF 364
               E          +L   AI +  KD   G     +KS+ I E ++++ V  +VG + 
Sbjct: 328 PQLSEEAFDELSDKIVLESKAIESLVKDFLKGDASPIVKSQEIFE-NQDSSVFQLVGKNH 386

Query: 365 VDVVLKSGKDVLIEIYAPWCGHCKKLEPVYEDLGRKLKKYDS-IIVAKMDGTLNETPIKD 423
            ++V    KDVL+  YAPWCGHCK+L P Y++L        S +++AK+D T N+  ++ 
Sbjct: 387 DEIVNDPKKDVLVLYYAPWCGHCKRLAPTYQELADTYANATSDVLIAKLDHTEND--VRG 444

Query: 424 FEWSGFPTIFFVKAGSKI-PLPYEGERSLKGFVDFLNKHATNTPISIDGVPEFED 477
               G+PTI     G K   + Y+G RSL    DF+ +   N    +DG   +E+
Sbjct: 445 VVIEGYPTIVLYPGGKKSESVVYQGSRSLDSLFDFIKE---NGHFDVDGKALYEE 496

Lambda     K      H
   0.317    0.137    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 687
Number of extensions: 45
Number of successful extensions: 16
Number of sequences better than 10.0: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 483
Length of database: 522
Length adjustment: 34
Effective length of query: 449
Effective length of database: 488
Effective search space:   219112
Effective search space used:   219112
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 26 (14.7 bits)
S2: 26 (14.6 bits)