>YNL189W SRP1 SGDID:S000005133, Chr XIV from 284261-285889, Verified
           ORF, "Karyopherin alpha homolog, forms a dimer with
           karyopherin beta Kap95p to mediate import of nuclear
           proteins, binds the nuclear localization signal of the
           substrate during import; may also play a role in
           regulation of protein degradation"
          Length = 542

 Score =  403 bits (1035), Expect = e-116
 Identities = 230/513 (44%), Positives = 313/513 (61%), Gaps = 25/513 (4%)

Query: 6   EARRKEFKK----NCDDTRRKREDLVVQIRKQQRECQLESKRAMVMANIGFEENNTYNLN 61
           E RR  FK     + D+ RR+R+   V++RK +R+  L  +R  +    G + +     +
Sbjct: 15  EYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADSDEEDESS 74

Query: 62  YAKGNQXXXXXXXXXXXXXXXXXXXLEMLKKIPTLAIGVRSNEYVTQLNSTRELRKLLSI 121
            +   Q                    ++ +++P +   + S++   QL++T + R++LS 
Sbjct: 75  VSADQQFYS-----------------QLQQELPQMTQQLNSDDMQEQLSATVKFRQILSR 117

Query: 122 EKGPPIQEVINSGVVPYIVEFLKYDDKTDLQFEAAWVITNIASGSQEQTKVVIDNNAVPH 181
           E  PPI  VI +GVVP +VEF++ +    LQ EAAW +TNIASG+  QTKVV+D +AVP 
Sbjct: 118 EHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPL 177

Query: 182 LVRLLSSEKEDVCEQAVWALGNIAGDSAECREYVLNQNSLPLLLKILRTSHKRTLIRNAA 241
            ++LL +   +V EQA+WALGN+AGDS + R+YVL  N++  +L +   S+K +LIR A 
Sbjct: 178 FIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLF-NSNKPSLIRTAT 236

Query: 242 WTLSNLCRG-KPAPKFEIVSKALPTLAALIYNDDEEILTDACWTLSYLSDGSNENINSVL 300
           WTLSNLCRG KP P + +VS+ALPTLA LIY+ D E L DACW +SYLSDG  E I +V+
Sbjct: 237 WTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVI 296

Query: 301 DAGVAERVVELLSHCSFLVQTPALRTVGNIVTGDDLQTDVVVKLGAVQXXXXXXXXXXXX 360
           D  + +R+VELLSH S LVQTPALR VGNIVTG+DLQT VV+  G +             
Sbjct: 297 DVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKEN 356

Query: 361 XXXEACWALSNITAGNISQIQAVIDNNVIPQLINILMKEDFEVRKEAAWAISNASSGGSE 420
              EACW +SNITAGN  QIQAVID N+IP L+ +L   +++ +KEA WAISNASSGG +
Sbjct: 357 IKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQ 416

Query: 421 LQ--IEYLVECGAIHSLSNLLDVEDANIISVTLEGLENILEMGENKKLRDNLPTNPYVHL 478
               I YLV  G I  L +LL++ D  II VTL+ LENIL+MGE  K    L  N     
Sbjct: 417 RPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADF 476

Query: 479 FEECDSVHKIDALQDRKVDNICNKAWKILYKYF 511
            E+   + KI   Q  + D I  KA+KI+  YF
Sbjct: 477 IEKAGGMEKIFNCQQNENDKIYEKAYKIIETYF 509

Lambda     K      H
   0.317    0.133    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 837
Number of extensions: 62
Number of successful extensions: 35
Number of sequences better than 10.0: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 545
Length of database: 542
Length adjustment: 35
Effective length of query: 510
Effective length of database: 507
Effective search space:   258570
Effective search space used:   258570
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 27 (15.2 bits)
S2: 27 (15.0 bits)