Query= PF10_0028 Pf Annotation|Plasmodium_falciparum_TIGR|(protein coding) hypothetical protein, conserved (248 letters)
>YPL043W NOP4 SGDID:S000005964, Chr XVI from 469936-471993, Verified
           ORF, "Nucleolar protein, essential for processing and
           maturation of 27S pre-rRNA and large ribosomal subunit
           biogenesis; constituent of 66S pre-ribosomal particles;
           contains four RNA recognition motifs (RRMs)"
          Length = 685

 Score = 57.8 bits (138), Expect = 6e-13
 Identities = 30/88 (34%), Positives = 48/88 (54%), Gaps = 1/88 (1%)

Query: 18  DGSTLYVSNLSSKITTAKLQDIFEKYGNIEKCYVISNPITKESRNFGFVTFNNSEDAENA 77
           D  TL+V ++   +T  +L D F  +  I+   V+ +   K SR FGFV+F   +D + A
Sbjct: 24  DMKTLFVRSIPQDVTDEQLADFFSNFAPIKHAVVVKDT-NKRSRGFGFVSFAVEDDTKEA 82

Query: 78  MNKANKMEIEGREINVEIAKRNEPHEPT 105
           + KA K +  G  + V+IAKR +  + T
Sbjct: 83  LAKARKTKFNGHILRVDIAKRRDRSKKT 110

 Score = 32.7 bits (73), Expect = 2e-05
 Identities = 21/81 (25%), Positives = 39/81 (48%), Gaps = 9/81 (11%)

Query: 35  KLQDIFEKYGNIEKCYVISNPITKESR--NFGFVTFNNSEDAENAMNKANKMEIEGREIN 92
           KL+ IF +YG + +  +   P  ++ +   F FVT     +   A+     ++I+GR++ 
Sbjct: 163 KLKKIFGRYGTVVEATI---PRKRDGKLCGFAFVTMKKISNCRIALENTKDLKIDGRKVA 219

Query: 93  VEIAKRNEPHEPTPGEYKGVQ 113
           V+ A +    E    +YK  Q
Sbjct: 220 VDFAVQKNRWE----DYKKAQ 236

 Score = 22.3 bits (46), Expect = 0.027
 Identities = 23/124 (18%), Positives = 43/124 (34%), Gaps = 30/124 (24%)

Query: 15  HKNDGSTLYVSNLSSKITTAKLQDIFEKYGNIEKCYVISNPITKESRNFGFVTFNNSEDA 74
           +K +  +++V N+    T   L   F K+G+++    + +  T  ++   FV F +    
Sbjct: 285 NKREDFSVFVRNVPYDATEESLAPHFSKFGSVKYALPVIDKSTGLAKGTAFVAFKDQYTY 344

Query: 75  ENAMNKAN---------------KMEIEGREINV---------------EIAKRNEPHEP 104
              +  A                +   EGR +++                 AKR E    
Sbjct: 345 NECIKNAPAAGSTSLLIGDDVMPEYVYEGRVLSITPTLVREDAGRMAEKNAAKRKEALGK 404

Query: 105 TPGE 108
            PGE
Sbjct: 405 APGE 408

 Score = 16.9 bits (32), Expect = 1.1
 Identities = 10/51 (19%), Positives = 19/51 (37%), Gaps = 1/51 (1%)

Query: 70  NSEDAENAMNKANKMEIEGREINVEIAKRN-EPHEPTPGEYKGVQNIVKRN 119
           N E    A NK     +  R +  +  + +  PH    G  K    ++ ++
Sbjct: 276 NKESKRKAQNKREDFSVFVRNVPYDATEESLAPHFSKFGSVKYALPVIDKS 326

 Score = 15.4 bits (28), Expect = 3.3
 Identities = 7/22 (31%), Positives = 12/22 (54%)

Query: 97  KRNEPHEPTPGEYKGVQNIVKR 118
           K+ E   PT  + K + + +KR
Sbjct: 651 KKEEATTPTNPDDKKMGDDIKR 672
Lambda     K      H
   0.309    0.127    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 309
Number of extensions: 13
Number of successful extensions: 6
Number of sequences better than 10.0: 1
Number of HSP's gapped: 5
Number of HSP's successfully gapped: 5
Length of query: 248
Length of database: 685
Length adjustment: 31
Effective length of query: 217
Effective length of database: 654
Effective search space:   141918
Effective search space used:   141918
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 24 (13.7 bits)
S2: 24 (13.9 bits)