>YMR217W GUA1 SGDID:S000004830, Chr XIII from 701789-703366,
           Verified ORF, "GMP synthase, an enzyme that catalyzes
           the second step in the biosynthesis of GMP from inosine
           5'-phosphate (IMP); transcription is not subject to
           regulation by guanine but is negatively regulated by
           nutrient starvation"
          Length = 525

 Score =  452 bits (1163), Expect = e-131
 Identities = 246/553 (44%), Positives = 341/553 (61%), Gaps = 41/553 (7%)

Query: 6   YDKILVLNFGSQYFHLIVKRLNNIKIFSETKDYGVELKDIKDMNIKGVILSGGPYSVTEA 65
           +D ILVL+FGSQY HLI +RL    I++E      ++ ++     KGVILSGGPYSV   
Sbjct: 11  FDTILVLDFGSQYSHLITRRLREFNIYAEMLPCTQKISEL-GWTPKGVILSGGPYSVYAE 69

Query: 66  GSPHLKKEVFEYFLEKKIPIFGICYGMQEIAVQMNGEVKKSKTSEYGCTDVNILRNDNIN 125
            +PH+   +F+      +PI GICYGMQE+A     +V +    EYG   + ++ + N  
Sbjct: 70  DAPHVDHAIFDL----NVPILGICYGMQELAWINGKQVGRGDKREYGPATLKVIDDSN-- 123

Query: 126 NITYCRNFGDSSSAMDLYSNYKLMNETCCLFENIKSDITTVWMNHNDEVTKIPENFYLVS 185
                             S +K MN++            TVWM+H D++  +P  +  ++
Sbjct: 124 ------------------SLFKGMNDS------------TVWMSHGDKLHGLPTGYKTIA 153

Query: 186 SSENCLICSIYNKEYNIYGVQYHPEVYESLDGELMFYNFAYNICKCKKQFDPIRYHELEL 245
           +S+N   C I ++   IYG+Q+HPEV  S  G+ +  NFA ++C  K+ +    + + E+
Sbjct: 154 TSDNSPYCGIVHETKPIYGIQFHPEVTHSTQGKTLLKNFAVDLCHAKQNWTMENFIDTEI 213

Query: 246 KNIEKYKHDHY-VIAAMSGGIDSTVAAAYTHKIFKERFFGIFIDNGLLRKNEAENVYTFL 304
             I K       VI A+SGG+DSTVA+    +   +RF  I +DNG+LR NEA NV   L
Sbjct: 214 NRIRKLVGPTAEVIGAVSGGVDSTVASKLMTEAIGDRFHAILVDNGVLRLNEAANVKKTL 273

Query: 305 KSTFPDMNITKIDASENFLSNLQGVTDPEQKRKIIGKLFIEEFEKAVNNIDIDINKT--F 362
                 +N+  +DASE FLS L+GVTDPE+KRKIIG  FI  FE+    I     K   F
Sbjct: 274 VEGL-GINLMVVDASEEFLSKLKGVTDPEKKRKIIGNTFIHVFEREAEKIKPKDGKEIQF 332

Query: 363 LLQGTLYPDIIESKCSKNLSDTIKTHHNVGGLPKNLKFKLFEPFKYLFKDDVKTLSRELN 422
           LLQGTLYPD+IES   K  S TIKTHHNVGGL +N+K KL EP + LFKD+V+ L   L 
Sbjct: 333 LLQGTLYPDVIESISFKGPSQTIKTHHNVGGLLENMKLKLIEPLRELFKDEVRHLGELLG 392

Query: 423 LPEEITNRHPFPGPGLAIRVIGEINKHKLNILREVDDIFINDLKQYGLYNQISQAFAVLL 482
           +P ++  RHPFPGPG+AIRV+GE+ K ++ I R+ D+I+I ++K+ GLYNQISQAFA LL
Sbjct: 393 IPHDLVWRHPFPGPGIAIRVLGEVTKEQVEIARKADNIYIEEIKKAGLYNQISQAFACLL 452

Query: 483 SSKSVGVRGDARSYDYVCVLRAVKTSSFMTANWYQIPYDILDKITTRILSEVKGVNRILY 542
             KSVGV GD R+YD V  LRA++T+ FMTA+W+   +  L K+ +RI++EV GV R+ Y
Sbjct: 453 PVKSVGVMGDQRTYDQVIALRAIETTDFMTADWFPFEHSFLKKVASRIVNEVDGVARVTY 512

Query: 543 DVSSKPPATIEFE 555
           D++SKPPAT+E+E
Sbjct: 513 DITSKPPATVEWE 525

Lambda     K      H
   0.319    0.138    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 750
Number of extensions: 26
Number of successful extensions: 10
Number of sequences better than 10.0: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 555
Length of database: 525
Length adjustment: 35
Effective length of query: 520
Effective length of database: 490
Effective search space:   254800
Effective search space used:   254800
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 27 (15.3 bits)
S2: 27 (15.0 bits)