>YMR173W DDR48 SGDID:S000004784, Chr XIII from 608688-609980, Verified
            ORF, "DNA damage-responsive protein, expression is
            increased in response to heat-shock stress or treatments
            that produce DNA lesions; contains multiple repeats of
            the amino acid sequence NNNDSYGS"
          Length = 430

 Score = 46.2 bits (108), Expect = 8e-09
 Identities = 73/338 (21%), Positives = 134/338 (39%), Gaps = 29/338 (8%)

Query: 701  SKVQQDIYNINCVNQTNGVNNIKHTNNIYSDHGYNIE--FIKNNDKQYYDENNRNSSNLV 758
            SKV+Q   N + +N  +  NN  + +N    +G N    +  NN+  Y   NN +  +  
Sbjct: 58   SKVRQQFSNTS-INDNDSNNNDSYGSNNNDSYGSNNNDSYGSNNNDSYGSNNNDSYGSNN 116

Query: 759  QMINKQKEKDRGDEESNRDINLKENNNDDGNLIIYYDDDGDQCY--DNNGCTTNLHDESI 816
                    K +    SN D +   +NN+D      Y  + +  Y  +NN    + +D+S 
Sbjct: 117  DDSYGSSNKKKSSYGSNNDDSYGSSNNNDS-----YGSNNNDSYGSNNNDSYGSNNDDSY 171

Query: 817  KEKNLSDVPFEKINENLNYKNHNDDMMNPLN-----FCNKKTDNGFEYIENLYFQKIND- 870
               N +   +   N++ +Y ++NDD     N     + +   D+     ++ Y    ND 
Sbjct: 172  GSSNKNKSSYGSNNDD-SYGSNNDDSYGSSNKKKSSYGSSNNDSYGSNNDDSYGSNNNDS 230

Query: 871  YTTNGITKDMKNNKKR-----NTNKLFTCK---ELFPKNKEYFILNKNESKHLVGYNISN 922
            Y +N       +NKK+     N +  +      + +  N +    + N++K   G + SN
Sbjct: 231  YGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNDDSYGSSNKNKSSYGSS-SN 289

Query: 923  DDNKIKVN---MYPYKDTKLNALHNYICVISPKNDNNNINCGEKICNHNNMLLNNSKTSN 979
            DD+    N    Y   + K ++  +        N++++     K  +      N+S  SN
Sbjct: 290  DDSYGSSNNDDSYGSSNKKKSSYGSNNDDSYGSNNDDSYGSSNKKKSSYGSSNNDSYGSN 349

Query: 980  NNEGCPFSYMNIKSLSTHNDNRNYDKNINPEDLSNLTD 1017
            N++    S     S  ++ND+     N N    SN  D
Sbjct: 350  NDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNDD 387

 Score = 40.4 bits (93), Expect = 4e-07
 Identities = 79/371 (21%), Positives = 131/371 (35%), Gaps = 52/371 (14%)

Query: 640 NNVVKNVTHLNTNDSFVYSKEEYNISSDEDNLMXXXXXXXXXXXXXXXXXXXXXXXXYGS 699
           +N   N    N NDS+  +  +   S++ D+                          YGS
Sbjct: 65  SNTSINDNDSNNNDSYGSNNNDSYGSNNNDS--YGSNNNDSYGSNNNDSYGSNNDDSYGS 122

Query: 700 HSKVQ-------QDIYNINCVNQTNGVNNI----KHTNNIYSDHGYNIEFIKNNDKQYYD 748
            +K +        D Y  +  N + G NN      + N+ Y  +  +     N +K  Y 
Sbjct: 123 SNKKKSSYGSNNDDSYGSSNNNDSYGSNNNDSYGSNNNDSYGSNNDDSYGSSNKNKSSYG 182

Query: 749 ENNRNS--SNLVQMINKQKEKDRGDEESNRDINLKENNNDDGNLIIYYDDDGDQCYDNNG 806
            NN +S  SN         +K      SN D     +NNDD      Y  + +  Y +N 
Sbjct: 183 SNNDDSYGSNNDDSYGSSNKKKSSYGSSNND--SYGSNNDDS-----YGSNNNDSYGSN- 234

Query: 807 CTTNLHDESIKEKNL----SDVPFEKINENLNYKNHNDDMMNPLNFCNKKTDNGFEYIEN 862
              + +  S K+K+     +D  +   N N +Y ++NDD     N    K+  G    ++
Sbjct: 235 -NDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNDDSYGSSN--KNKSSYGSSSNDD 291

Query: 863 LYFQKINDYTTNGITKDMKNNKKRNTNKLFTCKELFPKNKEYFILNKNESKHLVG----- 917
            Y    ND +     K   +    N +        +  N +    + N+ K   G     
Sbjct: 292 SYGSSNNDDSYGSSNKKKSSYGSNNDDS-------YGSNNDDSYGSSNKKKSSYGSSNND 344

Query: 918 -YNISNDD-----NKIKVNMYPYKDTKLNALHNYICVISPKNDNNNINCGEKICNHNNML 971
            Y  +NDD     NK K +     D    + +N          NN+ + G    N N+  
Sbjct: 345 SYGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNN----DSYGSNNDDSYGSSNRNKNSYG 400

Query: 972 LNNSKTSNNNE 982
            +N  +SNN++
Sbjct: 401 SSNYGSSNNDD 411

 Score = 40.4 bits (93), Expect = 4e-07
 Identities = 74/312 (23%), Positives = 118/312 (37%), Gaps = 48/312 (15%)

Query: 697 YGSHSKVQQDIYNINCVNQTNGVNNI----KHTNNIYSDHGYNIEFIKNNDKQYYDENNR 752
           YGS++    D Y  +  N + G NN      + N+ Y  +  +     N +K  Y  NN 
Sbjct: 130 YGSNN---DDSYGSSNNNDSYGSNNNDSYGSNNNDSYGSNNDDSYGSSNKNKSSYGSNND 186

Query: 753 NS--SNLVQMINKQKEKDRGDEESNRDINLKENNNDDGNLIIYYDDDGDQCYDNNGCTTN 810
           +S  SN         +K      SN D     +NNDD      Y  + +  Y +N    +
Sbjct: 187 DSYGSNNDDSYGSSNKKKSSYGSSNNDSY--GSNNDDS-----YGSNNNDSYGSNN--DD 237

Query: 811 LHDESIKEKNL----SDVPFEKINENLNYKNHNDDMMNPLNFCNKKTDNGFEYIENLYFQ 866
            +  S K+K+     +D  +   N N +Y ++NDD     N    K+  G    ++ Y  
Sbjct: 238 SYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNDDSYGSSN--KNKSSYGSSSNDDSYGS 295

Query: 867 KINDYTTNGITKDMKNNKKRNTNKLFTCKELFPKNKEYFILNKNESKHLVGYNISNDDNK 926
             ND  + G +   K++   N +  +        +  Y   NK +S     Y  SN+D+ 
Sbjct: 296 SNND-DSYGSSNKKKSSYGSNNDDSYGSNN----DDSYGSSNKKKSS----YGSSNNDSY 346

Query: 927 IKVNMYPYKDTKLNALHNYICVISPKNDNNNINCGEKICNHNNMLLNNSKTSNNNEGCPF 986
              N   Y  +            S    NN+ + G      NN   N+S  SNN++    
Sbjct: 347 GSNNDDSYGSSNKKK--------SSYGSNNDDSYGSS----NN---NDSYGSNNDDSYGS 391

Query: 987 SYMNIKSLSTHN 998
           S  N  S  + N
Sbjct: 392 SNRNKNSYGSSN 403

 Score = 39.3 bits (90), Expect = 1e-06
 Identities = 72/311 (23%), Positives = 114/311 (36%), Gaps = 57/311 (18%)

Query: 719  VNNIKHTNNIYSDHGYNIEFIKNNDKQYYDE-NNRNSSNLVQMINKQKEKDRGDEE---- 773
            V    ++NN  +D G       NN   Y  +  N    + V     +  +DR D+     
Sbjct: 7    VKQFANSNNNNNDSG------NNNQGDYVTKAENMIGEDRVNQFKSKIGEDRFDKMESKV 60

Query: 774  ----SNRDINLKENNNDDGNLIIYYDDDGDQCYDNNGCTTNLHDESIKEKNLSDVPFEKI 829
                SN  IN  ++NN+D      Y  + +  Y +N      +++S    N         
Sbjct: 61   RQQFSNTSINDNDSNNNDS-----YGSNNNDSYGSN------NNDSYGSNNNDSYGS--- 106

Query: 830  NENLNYKNHNDDMMNPLNFCNKKTDNGFEYIENLYFQKINDY--TTNGITKDMKNNKKRN 887
            N N +Y ++NDD     N   KK+  G    ++      ND   + N  +    NN    
Sbjct: 107  NNNDSYGSNNDDSYGSSN--KKKSSYGSNNDDSYGSSNNNDSYGSNNNDSYGSNNNDSYG 164

Query: 888  TNKLFTCKELFPKNKEYFILNKNESKHLVGYNISNDDNKIKVNMYPY-KDTKLNALHNYI 946
            +N           +  Y   NKN+S     Y  +NDD+    N   Y    K  + +   
Sbjct: 165  SNN----------DDSYGSSNKNKSS----YGSNNDDSYGSNNDDSYGSSNKKKSSYG-- 208

Query: 947  CVISPKNDNNNINCGEKICNHNNMLLNNSKTSNNNEGCPFSYMNIKSLSTHNDNRNYDKN 1006
               S  ND+   N  +   ++NN    +S  SNN++    S     S  ++ND+     N
Sbjct: 209  ---SSNNDSYGSNNDDSYGSNNN----DSYGSNNDDSYGSSNKKKSSYGSNNDDSYGSSN 261

Query: 1007 INPEDLSNLTD 1017
             N    SN  D
Sbjct: 262  NNDSYGSNNDD 272

 Score = 37.7 bits (86), Expect = 3e-06
 Identities = 58/275 (21%), Positives = 98/275 (35%), Gaps = 28/275 (10%)

Query: 633 SNDYIYCNNVVKNVTHLNTNDSFVYSKEEYNISSDEDNLMXXXXXXXXXXXXXXXXXXXX 692
           +ND  Y ++   +    N NDS+  +  +   S+++D+                      
Sbjct: 133 NNDDSYGSSNNNDSYGSNNNDSYGSNNNDSYGSNNDDSYGSSNKNKSSYGSNNDDSYGSN 192

Query: 693 XXXXYGSHSKVQ-------QDIYNINCVNQTNGVNNIKHTNNIYSDHGYN----IEFIKN 741
               YGS +K +        D Y  N  +     NN  + +N    +G +      +  N
Sbjct: 193 NDDSYGSSNKKKSSYGSSNNDSYGSNNDDSYGSNNNDSYGSNNDDSYGSSNKKKSSYGSN 252

Query: 742 NDKQYYDENNRNS--SNLVQMINKQKEKDRGDEESNRDINLKENNNDD-----GNLIIYY 794
           ND  Y   NN +S  SN         +       S+ D +   +NNDD           Y
Sbjct: 253 NDDSYGSSNNNDSYGSNNDDSYGSSNKNKSSYGSSSNDDSYGSSNNDDSYGSSNKKKSSY 312

Query: 795 DDDGDQCYDNNGCTTNLHDESIKEKNLSDVPFEKINENLNYKNHNDDMMNPLNFCNKKTD 854
             + D  Y +N      +D+S    N     +   N N +Y ++NDD     N   KK+ 
Sbjct: 313 GSNNDDSYGSN------NDDSYGSSNKKKSSYGSSN-NDSYGSNNDDSYGSSN--KKKSS 363

Query: 855 NGFEYIENLYFQKIND-YTTNGITKDMKNNKKRNT 888
            G    ++      ND Y +N       +N+ +N+
Sbjct: 364 YGSNNDDSYGSSNNNDSYGSNNDDSYGSSNRNKNS 398

 Score = 30.4 bits (67), Expect = 5e-04
 Identities = 45/215 (20%), Positives = 82/215 (38%), Gaps = 43/215 (20%)

Query: 826  FEKINENLNYKNHNDDMMNPLN------------------FCNKKTDNGFEYIENLYFQK 867
            F+K+ +  N  N+N+D  N                     F +K  ++ F+ +E+   Q+
Sbjct: 4    FDKVKQFANSNNNNNDSGNNNQGDYVTKAENMIGEDRVNQFKSKIGEDRFDKMESKVRQQ 63

Query: 868  INDYTTNGITKDMKNNKKRNTNKLFTCKE---LFPKNKEYFILNKNESKHLVGYNISNDD 924
             ++ + N    +  ++   N N  +           N + +  N N+S     Y  +NDD
Sbjct: 64   FSNTSINDNDSNNNDSYGSNNNDSYGSNNNDSYGSNNNDSYGSNNNDS-----YGSNNDD 118

Query: 925  -----NKIKVNMYPYKDTKLNALHNYICVISPKNDNNNINCGEKICNHNNMLLNNSKTSN 979
                 NK K +     D    + +N        ND+   N  +   ++NN    +S  SN
Sbjct: 119  SYGSSNKKKSSYGSNNDDSYGSSNN--------NDSYGSNNNDSYGSNNN----DSYGSN 166

Query: 980  NNEGCPFSYMNIKSLSTHNDNRNYDKNINPEDLSN 1014
            N++    S  N  S  ++ND+     N +    SN
Sbjct: 167  NDDSYGSSNKNKSSYGSNNDDSYGSNNDDSYGSSN 201

 Score = 27.7 bits (60), Expect = 0.003
 Identities = 34/171 (19%), Positives = 65/171 (38%), Gaps = 16/171 (9%)

Query: 697 YGSHSKVQQDIYNINCVNQTNGVNNI-------KHTNNIYSDHGYNIEFIKNNDKQYYDE 749
           YGS++    D Y  +  N + G NN        K+ ++  S    +     NND  Y   
Sbjct: 249 YGSNN---DDSYGSSNNNDSYGSNNDDSYGSSNKNKSSYGSSSNDDSYGSSNNDDSYGSS 305

Query: 750 NNRNSSNLVQMINKQKEKDRGDEESNRDINLKENNNDDGNLIIYYDDDGDQCYDNNGCTT 809
           N + SS      N        +++S    N K+++    N   Y  ++ D    +N   +
Sbjct: 306 NKKKSS---YGSNNDDSYGSNNDDSYGSSNKKKSSYGSSNNDSYGSNNDDSYGSSNKKKS 362

Query: 810 NL---HDESIKEKNLSDVPFEKINENLNYKNHNDDMMNPLNFCNKKTDNGF 857
           +    +D+S    N +D      +++    N N +     N+ +   D+ +
Sbjct: 363 SYGSNNDDSYGSSNNNDSYGSNNDDSYGSSNRNKNSYGSSNYGSSNNDDSY 413

 Score = 26.9 bits (58), Expect = 0.005
 Identities = 20/92 (21%), Positives = 40/92 (43%), Gaps = 15/92 (16%)

Query: 1256 YEEFKKYDHMNNNMTDIYQSNYPLYSTNQEKETTDSNPEKINYRLLEERKKKIYLNNYYN 1315
            +++ K++ + NNN  D   +N   Y T  E    +    +   ++ E+R         ++
Sbjct: 4    FDKVKQFANSNNNNNDSGNNNQGDYVTKAENMIGEDRVNQFKSKIGEDR---------FD 54

Query: 1316 MIKSVDRDNYIYNVPFVSTIINDNNVRYNNEF 1347
             ++S  R        F +T INDN+   N+ +
Sbjct: 55   KMESKVRQQ------FSNTSINDNDSNNNDSY 80

 Score = 25.8 bits (55), Expect = 0.011
 Identities = 16/68 (23%), Positives = 27/68 (39%), Gaps = 1/68 (1%)

Query: 1231 NNPGELIKNGENNSVNLKNNKVINSYEEFKKYDHMNNNMTDIYQSNYPLYSTNQEKETTD 1290
            +N  +   +  N+S    NN    S  +   Y   N N +    +N   Y +N +     
Sbjct: 141  SNNNDSYGSNNNDSYGSNNNDSYGSNND-DSYGSSNKNKSSYGSNNDDSYGSNNDDSYGS 199

Query: 1291 SNPEKINY 1298
            SN +K +Y
Sbjct: 200  SNKKKSSY 207

 Score = 25.0 bits (53), Expect = 0.019
 Identities = 16/60 (26%), Positives = 26/60 (43%), Gaps = 1/60 (1%)

Query: 1240 GENNSVNL-KNNKVINSYEEFKKYDHMNNNMTDIYQSNYPLYSTNQEKETTDSNPEKINY 1298
            G NN  +   +NK  +SY       + +NN      +N   Y +N +     SN +K +Y
Sbjct: 190  GSNNDDSYGSSNKKKSSYGSSNNDSYGSNNDDSYGSNNNDSYGSNNDDSYGSSNKKKSSY 249

 Score = 23.9 bits (50), Expect = 0.043
 Identities = 15/60 (25%), Positives = 25/60 (41%), Gaps = 3/60 (5%)

Query: 1239 NGENNSVNLKNNKVINSYEEFKKYDHMNNNMTDIYQSNYPLYSTNQEKETTDSNPEKINY 1298
            +  N+S    NN   +SY       + +NN      +N   Y +N +     SN +K +Y
Sbjct: 74   SNNNDSYGSNNN---DSYGSNNNDSYGSNNNDSYGSNNNDSYGSNNDDSYGSSNKKKSSY 130

 Score = 23.9 bits (50), Expect = 0.043
 Identities = 17/61 (27%), Positives = 25/61 (40%), Gaps = 2/61 (3%)

Query: 1240 GENNSVNLKNNKVINSYEEFKKYDHMNNNMTDIYQS--NYPLYSTNQEKETTDSNPEKIN 1297
            G NN+ +  +N   +     KK     +N  D Y S  N   Y +N +     SN  K +
Sbjct: 224  GSNNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNDDSYGSSNKNKSS 283

Query: 1298 Y 1298
            Y
Sbjct: 284  Y 284

 Score = 23.5 bits (49), Expect = 0.056
 Identities = 15/58 (25%), Positives = 27/58 (46%)

Query: 1633 SNEEKKKFQSHGYKNDNMLLNNTYFNNKNCFSYDSIKKNDYNLLETSSNHTSTFLNYD 1690
            SN++K  + S+   +     NN  + + N  SY S  KN  +   +S++ +    N D
Sbjct: 242  SNKKKSSYGSNNDDSYGSSNNNDSYGSNNDDSYGSSNKNKSSYGSSSNDDSYGSSNND 299

 Score = 23.5 bits (49), Expect = 0.056
 Identities = 22/93 (23%), Positives = 33/93 (35%), Gaps = 3/93 (3%)

Query: 697 YGSHSKVQQDIYNINCVNQTNGVNNIKHTNN--IYSDHGYNIEFIKNNDKQYYDENNRNS 754
           YGS +       N +    +N   +   +NN   Y     N  +  NND  Y   +NRN 
Sbjct: 338 YGSSNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNDDSY-GSSNRNK 396

Query: 755 SNLVQMINKQKEKDRGDEESNRDINLKENNNDD 787
           ++           D     SNR    +   +DD
Sbjct: 397 NSYGSSNYGSSNNDDSYGSSNRGGRNQYGGDDD 429

 Score = 23.1 bits (48), Expect = 0.073
 Identities = 18/84 (21%), Positives = 34/84 (40%), Gaps = 2/84 (2%)

Query: 1242 NNSVNLKNNKVINSYEEFKKYDHMNNNMTDIYQSNYPLYSTNQEKETTDSNPEKINYRLL 1301
            N S+N  ++   +SY       + +NN      +N   Y +N       +N +  +Y   
Sbjct: 66   NTSINDNDSNNNDSYGSNNNDSYGSNNNDSYGSNNNDSYGSNNNDSYGSNNDD--SYGSS 123

Query: 1302 EERKKKIYLNNYYNMIKSVDRDNY 1325
             ++K     NN  +   S + D+Y
Sbjct: 124  NKKKSSYGSNNDDSYGSSNNNDSY 147

 Score = 23.1 bits (48), Expect = 0.073
 Identities = 15/57 (26%), Positives = 25/57 (43%)

Query: 311 NNEYDGCNFNDMLNNNCKSLNVHKSICLDKSNMNIDEEYFDMKEKTMENEELINNSY 367
           NN+  G N +D   ++ K+ + + S   D    N D+ Y    +K        N+SY
Sbjct: 159 NNDSYGSNNDDSYGSSNKNKSSYGSNNDDSYGSNNDDSYGSSNKKKSSYGSSNNDSY 215

 Score = 23.1 bits (48), Expect = 0.073
 Identities = 18/79 (22%), Positives = 30/79 (37%)

Query: 289 NNNILEYKKEQKNYFISPQNIINNEYDGCNFNDMLNNNCKSLNVHKSICLDKSNMNIDEE 348
           +NN   Y    KN      +  ++ Y   N +D   ++ K  + + S   D    N D+ 
Sbjct: 268 SNNDDSYGSSNKNKSSYGSSSNDDSYGSSNNDDSYGSSNKKKSSYGSNNDDSYGSNNDDS 327

Query: 349 YFDMKEKTMENEELINNSY 367
           Y    +K        N+SY
Sbjct: 328 YGSSNKKKSSYGSSNNDSY 346

 Score = 22.7 bits (47), Expect = 0.096
 Identities = 17/71 (23%), Positives = 27/71 (38%), Gaps = 1/71 (1%)

Query: 1228 SSINNPGELIKNGENNSVNLKNNKVINSYEEFKKYDHMNNNMTDIYQSNYPLYSTNQEKE 1287
            SS N+      N + +S    N+    S  +   Y   N   +    SN   Y +N +  
Sbjct: 295  SSNNDDSYGSSNKKKSSYGSNNDDSYGSNND-DSYGSSNKKKSSYGSSNNDSYGSNNDDS 353

Query: 1288 TTDSNPEKINY 1298
               SN +K +Y
Sbjct: 354  YGSSNKKKSSY 364

 Score = 22.3 bits (46), Expect = 0.13
 Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 4/67 (5%)

Query: 1631 FQSNEEKKKFQ-SHGYKNDNMLLNNTYFNNKNCFSYDSIKKNDYNLLETSSNHTSTFLNY 1689
            F   E K + Q S+   NDN   NN  + + N  SY S   + Y    +++N +    N 
Sbjct: 53   FDKMESKVRQQFSNTSINDNDSNNNDSYGSNNNDSYGSNNNDSYG---SNNNDSYGSNNN 109

Query: 1690 DLYRTDS 1696
            D Y +++
Sbjct: 110  DSYGSNN 116

 Score = 21.9 bits (45), Expect = 0.16
 Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 5/51 (9%)

Query: 1638 KKFQSHGYKNDNML---LNNTYFNNKNCFSYDSIKKNDYNLLETSSNHTST 1685
            KK  S+G  ND+      NN  + + N  SY S  +N  +    SSN+ S+
Sbjct: 359  KKKSSYGSNNDDSYGSSNNNDSYGSNNDDSYGSSNRNKNSY--GSSNYGSS 407

 Score = 21.6 bits (44), Expect = 0.21
 Identities = 25/108 (23%), Positives = 43/108 (39%), Gaps = 5/108 (4%)

Query: 1240 GENNSVNL-KNNKVINSYEEFKKYDHMNNNMTDIYQS-NYPLYSTNQEKETTDSNPEKIN 1297
            G NN  +   +NK  +SY       + ++N  D Y S N   Y +N       +N +   
Sbjct: 113  GSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNNDSYGSNNNDSYGSNNDDSYG 172

Query: 1298 YRLLEERKKKIYLNNYYNMIKSVDRDNYIYNVPFVSTIINDNNVRYNN 1345
                  + K  Y +N  +   S + D+Y  +    S+  + NN  Y +
Sbjct: 173  ---SSNKNKSSYGSNNDDSYGSNNDDSYGSSNKKKSSYGSSNNDSYGS 217

 Score = 21.6 bits (44), Expect = 0.21
 Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 8/53 (15%)

Query: 1638 KKFQSHGYKNDNMLLNNTYFNNKNCFSYDSIKKNDYNLLETSSNHTSTFLNYD 1690
            KK  S+G  ND+   +    NN + +   + KK+ Y     SSN+ S   N D
Sbjct: 307  KKKSSYGSNNDDSYGS----NNDDSYGSSNKKKSSYG----SSNNDSYGSNND 351

 Score = 21.2 bits (43), Expect = 0.28
 Identities = 11/41 (26%), Positives = 19/41 (46%)

Query: 1633 SNEEKKKFQSHGYKNDNMLLNNTYFNNKNCFSYDSIKKNDY 1673
            SN++K  + S+   +     NN  + + N  SY S   + Y
Sbjct: 123  SNKKKSSYGSNNDDSYGSSNNNDSYGSNNNDSYGSNNNDSY 163

 Score = 21.2 bits (43), Expect = 0.28
 Identities = 17/71 (23%), Positives = 31/71 (43%), Gaps = 7/71 (9%)

Query: 1633 SNEEKKKF-----QSHGYKNDNML--LNNTYFNNKNCFSYDSIKKNDYNLLETSSNHTST 1685
            SN++K  +      S+G  ND+     NN  + + N  SY S  K   +    + +   +
Sbjct: 200  SNKKKSSYGSSNNDSYGSNNDDSYGSNNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYGS 259

Query: 1686 FLNYDLYRTDS 1696
              N D Y +++
Sbjct: 260  SNNNDSYGSNN 270

 Score = 21.2 bits (43), Expect = 0.28
 Identities = 27/118 (22%), Positives = 46/118 (38%), Gaps = 6/118 (5%)

Query: 1231 NNPGELIKNGENNSVNLKNNKVINSYEEFKKYDHMNNNMTDIYQS---NYPLYSTNQEKE 1287
            NN      + +  S    NN   +SY      D   +N  D Y S   N   Y ++   +
Sbjct: 234  NNDDSYGSSNKKKSSYGSNND--DSYGSSNNNDSYGSNNDDSYGSSNKNKSSYGSSSNDD 291

Query: 1288 TTDSNPEKINYRLLEERKKKIYLNNYYNMIKSVDRDNYIYNVPFVSTIINDNNVRYNN 1345
            +  S+    +Y     +KK  Y +N  +   S + D+Y  +    S+  + NN  Y +
Sbjct: 292  SYGSSNNDDSYG-SSNKKKSSYGSNNDDSYGSNNDDSYGSSNKKKSSYGSSNNDSYGS 348

 Score = 21.2 bits (43), Expect = 0.28
 Identities = 21/82 (25%), Positives = 29/82 (35%), Gaps = 13/82 (15%)

Query: 1228 SSINNPGELIKNGENNSVNLKNNKVINSYEEFKKYDHMNNNMTDIYQS-----------N 1276
            SS NN      N ++   + KN     S      Y   NN+  D Y S           N
Sbjct: 259  SSNNNDSYGSNNDDSYGSSNKNKSSYGSSSNDDSYGSSNND--DSYGSSNKKKSSYGSNN 316

Query: 1277 YPLYSTNQEKETTDSNPEKINY 1298
               Y +N +     SN +K +Y
Sbjct: 317  DDSYGSNNDDSYGSSNKKKSSY 338

 Score = 21.2 bits (43), Expect = 0.28
 Identities = 16/61 (26%), Positives = 25/61 (40%), Gaps = 2/61 (3%)

Query: 1240 GENNSVNLKNNKVINSYEEFKKYDHMNNNMTDIYQS--NYPLYSTNQEKETTDSNPEKIN 1297
            G +N+ +  +N   +     KK     +N  D Y S  N   Y +N +     SN  K +
Sbjct: 339  GSSNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNDDSYGSSNRNKNS 398

Query: 1298 Y 1298
            Y
Sbjct: 399  Y 399

 Score = 20.8 bits (42), Expect = 0.36
 Identities = 14/44 (31%), Positives = 23/44 (52%), Gaps = 4/44 (9%)

Query: 1069 NINNVNKFDNFKTYN--MYPNENNPIEVESNSEMILVHTNNNDS 1110
            N N+ N  D++ + N   Y + NN     +N++     +NNNDS
Sbjct: 70   NDNDSNNNDSYGSNNNDSYGSNNNDSYGSNNNDS--YGSNNNDS 111

 Score = 20.4 bits (41), Expect = 0.48
 Identities = 16/73 (21%), Positives = 28/73 (38%), Gaps = 8/73 (10%)

Query: 1228 SSINNPGELIKNGEN----NSVNLKNNKV----INSYEEFKKYDHMNNNMTDIYQSNYPL 1279
            S  NN G+ +   EN    + VN   +K+     +  E   +    N ++ D   +N   
Sbjct: 20   SGNNNQGDYVTKAENMIGEDRVNQFKSKIGEDRFDKMESKVRQQFSNTSINDNDSNNNDS 79

Query: 1280 YSTNQEKETTDSN 1292
            Y +N       +N
Sbjct: 80   YGSNNNDSYGSNN 92

 Score = 20.4 bits (41), Expect = 0.48
 Identities = 14/71 (19%), Positives = 28/71 (39%)

Query: 1228 SSINNPGELIKNGENNSVNLKNNKVINSYEEFKKYDHMNNNMTDIYQSNYPLYSTNQEKE 1287
            SS  N      +  ++S    NN         KK  + +NN      +N   Y ++ +K+
Sbjct: 276  SSNKNKSSYGSSSNDDSYGSSNNDDSYGSSNKKKSSYGSNNDDSYGSNNDDSYGSSNKKK 335

Query: 1288 TTDSNPEKINY 1298
            ++  +    +Y
Sbjct: 336  SSYGSSNNDSY 346

 Score = 20.0 bits (40), Expect = 0.62
 Identities = 19/103 (18%), Positives = 39/103 (37%), Gaps = 2/103 (1%)

Query: 1067 NYNINNVNKFDNFKTYNMYPNENNPIEVESNSEMILVHTNNNDSTNVFNQALIKNKKNEN 1126
            +Y  NN + + +    +   +        SN++     +NNNDS    N     +  N++
Sbjct: 103  SYGSNNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNNDSYGSNNNDS 162

Query: 1127 VVQVDAHQMVLNNVTELADNVSRDMCRGEIIQDETTYQEDNKK 1169
                +      +N  + +   + D   G    ++ +Y   NKK
Sbjct: 163  YGSNNDDSYGSSNKNKSSYGSNNDDSYGS--NNDDSYGSSNKK 203

 Score = 20.0 bits (40), Expect = 0.62
 Identities = 20/101 (19%), Positives = 33/101 (32%), Gaps = 6/101 (5%)

Query: 1231 NNPGELIKNGENNSVNLKNNKVINSYEEFKKYDHMNNNMTDIYQSNYPLYSTNQEKETTD 1290
            NN      + +N S    NN           Y   N   +    SN   Y +N +     
Sbjct: 166  NNDDSYGSSNKNKSSYGSNNDDSYGSNNDDSYGSSNKKKSSYGSSNNDSYGSNNDDSYGS 225

Query: 1291 SNPEKI------NYRLLEERKKKIYLNNYYNMIKSVDRDNY 1325
            +N +        +Y    ++K     NN  +   S + D+Y
Sbjct: 226  NNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSY 266

 Score = 20.0 bits (40), Expect = 0.62
 Identities = 58/308 (18%), Positives = 100/308 (32%), Gaps = 67/308 (21%)

Query: 549 NENKNTDDYRVNDDSNTCVIN--FVECINKENQNVITEKGKTNTRDDDNSKGXXXXXXXX 606
           + NKN   Y  N+D +    N       NK+  +  +    +   ++D+S G        
Sbjct: 173 SSNKNKSSYGSNNDDSYGSNNDDSYGSSNKKKSSYGSSNNDSYGSNNDDSYG-------- 224

Query: 607 XXXXXXXXXXXXXXXXXXXXXXXFMHSNDYIY-CNNVVKNVTHLNTNDSFVYSKEEYNIS 665
                                  +  +ND  Y  +N  K+    N +DS+  S    +  
Sbjct: 225 -----------------SNNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYG 267

Query: 666 SDEDNLMXXXXXXXXXXXXXXXXXXXXXXXXYGSHSKVQQDI---YNINCVNQTNGVNNI 722
           S+ D+                          YGS +K +       N +    +N  ++ 
Sbjct: 268 SNNDD-------------------------SYGSSNKNKSSYGSSSNDDSYGSSNNDDSY 302

Query: 723 KHTNNIYSDHGYNIE--FIKNNDKQYYDENNRNSSNLVQMINKQKEKDRGDE---ESNRD 777
             +N   S +G N +  +  NND  Y   N + SS      N        D+    SN+ 
Sbjct: 303 GSSNKKKSSYGSNNDDSYGSNNDDSYGSSNKKKSS--YGSSNNDSYGSNNDDSYGSSNKK 360

Query: 778 INLKENNNDD----GNLIIYYDDDGDQCYDNNGCTTNLHDESIKEKNLSDVPFEKINENL 833
            +   +NNDD     N    Y  + D  Y ++    N +  S    + +D  +   N   
Sbjct: 361 KSSYGSNNDDSYGSSNNNDSYGSNNDDSYGSSNRNKNSYGSSNYGSSNNDDSYGSSNRGG 420

Query: 834 NYKNHNDD 841
             +   DD
Sbjct: 421 RNQYGGDD 428

 Score = 19.6 bits (39), Expect = 0.81
 Identities = 16/53 (30%), Positives = 24/53 (45%), Gaps = 8/53 (15%)

Query: 1638 KKFQSHGYKNDNMLLNNTYFNNKNCFSYDSIKKNDYNLLETSSNHTSTFLNYD 1690
            K   S+G  ND+   +N    N + +   + KK+ Y     SSN+ S   N D
Sbjct: 176  KNKSSYGSNNDDSYGSN----NDDSYGSSNKKKSSYG----SSNNDSYGSNND 220

 Score = 19.6 bits (39), Expect = 0.81
 Identities = 15/59 (25%), Positives = 27/59 (45%), Gaps = 2/59 (3%)

Query: 311 NNEYDGCNFNDMLNNNCKSLNVHKSICLDKS--NMNIDEEYFDMKEKTMENEELINNSY 367
           NN+  G N +D   ++ K+ + + S   D S  + N D+ Y    +K        ++SY
Sbjct: 262 NNDSYGSNNDDSYGSSNKNKSSYGSSSNDDSYGSSNNDDSYGSSNKKKSSYGSNNDDSY 320

 Score = 19.6 bits (39), Expect = 0.81
 Identities = 14/66 (21%), Positives = 27/66 (40%)

Query: 1631 FQSNEEKKKFQSHGYKNDNMLLNNTYFNNKNCFSYDSIKKNDYNLLETSSNHTSTFLNYD 1690
            + SN +     S+  K+     NN  + + N  SY S  K   +    + +   +  N D
Sbjct: 320  YGSNNDDSYGSSNKKKSSYGSSNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNND 379

Query: 1691 LYRTDS 1696
             Y +++
Sbjct: 380  SYGSNN 385

 Score = 19.2 bits (38), Expect = 1.1
 Identities = 9/31 (29%), Positives = 16/31 (51%)

Query: 296 KKEQKNYFISPQNIINNEYDGCNFNDMLNNN 326
           +++  N  I+  +  NN+  G N ND   +N
Sbjct: 61  RQQFSNTSINDNDSNNNDSYGSNNNDSYGSN 91

 Score = 18.9 bits (37), Expect = 1.4
 Identities = 15/57 (26%), Positives = 24/57 (42%), Gaps = 2/57 (3%)

Query: 311 NNEYDGCNFNDMLNNNCKSLNVHKSICLDKSNMNIDEEYFDMKEKTMENEELINNSY 367
           NN+  G N ND   +N  + + + S   D    N D+ Y    +K        ++SY
Sbjct: 84  NNDSYGSNNNDSYGSN--NNDSYGSNNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSY 138

 Score = 18.9 bits (37), Expect = 1.4
 Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 6/60 (10%)

Query: 1634 NEEKKKFQSHGYKNDNMLLNN--TY-FNNKNCFSYDSIKKNDYNLLETSSNHTSTFLNYD 1690
            +  KKK       ND+   NN  +Y  +NK   SY S   + Y    +S+N+ S   N D
Sbjct: 330  SSNKKKSSYGSSNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYG---SSNNNDSYGSNND 386

 Score = 18.5 bits (36), Expect = 1.8
 Identities = 6/28 (21%), Positives = 15/28 (53%)

Query: 1431 NNKYFNEEKDNYKILGQEEKNISTNEDN 1458
            N+ Y +   D+Y    +++ +  +N D+
Sbjct: 109  NDSYGSNNDDSYGSSNKKKSSYGSNNDD 136

 Score = 18.5 bits (36), Expect = 1.8
 Identities = 8/19 (42%), Positives = 10/19 (52%)

Query: 1653 NNTYFNNKNCFSYDSIKKN 1671
            NN  + + N  SY S  KN
Sbjct: 159  NNDSYGSNNDDSYGSSNKN 177

 Score = 18.5 bits (36), Expect = 1.8
 Identities = 6/28 (21%), Positives = 15/28 (53%)

Query: 1431 NNKYFNEEKDNYKILGQEEKNISTNEDN 1458
            N+ Y +   D+Y    +++ +  +N D+
Sbjct: 228  NDSYGSNNDDSYGSSNKKKSSYGSNNDD 255

 Score = 18.5 bits (36), Expect = 1.8
 Identities = 6/28 (21%), Positives = 15/28 (53%)

Query: 1431 NNKYFNEEKDNYKILGQEEKNISTNEDN 1458
            N+ Y +   D+Y    +++ +  +N D+
Sbjct: 343  NDSYGSNNDDSYGSSNKKKSSYGSNNDD 370

 Score = 18.5 bits (36), Expect = 1.8
 Identities = 16/55 (29%), Positives = 18/55 (32%), Gaps = 4/55 (7%)

Query: 1240 GENN--SVNLKNNKVINSYEEFKKYDHMNNNMTDIYQSNYPLYSTNQEKETTDSN 1292
            G NN  S    NN           Y   N N      SNY   S+N +     SN
Sbjct: 365  GSNNDDSYGSSNNNDSYGSNNDDSYGSSNRNKNSYGSSNYG--SSNNDDSYGSSN 417

 Score = 18.1 bits (35), Expect = 2.4
 Identities = 11/53 (20%), Positives = 21/53 (39%)

Query: 1074 NKFDNFKTYNMYPNENNPIEVESNSEMILVHTNNNDSTNVFNQALIKNKKNEN 1126
            ++FD  ++       N  I    ++      +NNNDS    N     +  N++
Sbjct: 51   DRFDKMESKVRQQFSNTSINDNDSNNNDSYGSNNNDSYGSNNNDSYGSNNNDS 103

 Score = 18.1 bits (35), Expect = 2.4
 Identities = 12/35 (34%), Positives = 15/35 (42%), Gaps = 1/35 (2%)

Query: 311 NNEYDGCNFNDML-NNNCKSLNVHKSICLDKSNMN 344
           NN+  G N ND   +NN  S   +       SN N
Sbjct: 143 NNDSYGSNNNDSYGSNNNDSYGSNNDDSYGSSNKN 177

 Score = 18.1 bits (35), Expect = 2.4
 Identities = 6/28 (21%), Positives = 14/28 (50%)

Query: 1431 NNKYFNEEKDNYKILGQEEKNISTNEDN 1458
            N+ Y +   D+Y    + + +  +N D+
Sbjct: 160  NDSYGSNNDDSYGSSNKNKSSYGSNNDD 187

 Score = 17.7 bits (34), Expect = 3.1
 Identities = 10/48 (20%), Positives = 21/48 (43%)

Query: 1079 FKTYNMYPNENNPIEVESNSEMILVHTNNNDSTNVFNQALIKNKKNEN 1126
            F   ++  N++N  +   ++      +NNNDS    N     +  N++
Sbjct: 64   FSNTSINDNDSNNNDSYGSNNNDSYGSNNNDSYGSNNNDSYGSNNNDS 111

 Score = 17.7 bits (34), Expect = 3.1
 Identities = 10/44 (22%), Positives = 19/44 (43%)

Query: 1653 NNTYFNNKNCFSYDSIKKNDYNLLETSSNHTSTFLNYDLYRTDS 1696
            NN  + + N  SY S  K   +    + +   +  N D Y +++
Sbjct: 108  NNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNN 151

 Score = 17.7 bits (34), Expect = 3.1
 Identities = 9/29 (31%), Positives = 12/29 (41%)

Query: 452 ENIITERGYLCKQNDDKYLLNVVGAINKY 480
           +N      Y    NDD Y  +  G  N+Y
Sbjct: 396 KNSYGSSNYGSSNNDDSYGSSNRGGRNQY 424

 Score = 17.3 bits (33), Expect = 4.0
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1104 HTNNNDSTN 1112
            + NNNDS N
Sbjct: 14   NNNNNDSGN 22

 Score = 17.3 bits (33), Expect = 4.0
 Identities = 16/77 (20%), Positives = 28/77 (36%)

Query: 1249 NNKVINSYEEFKKYDHMNNNMTDIYQSNYPLYSTNQEKETTDSNPEKINYRLLEERKKKI 1308
            +NK  +SY       + +NN      SN    S       +  +    +Y    ++K   
Sbjct: 305  SNKKKSSYGSNNDDSYGSNNDDSYGSSNKKKSSYGSSNNDSYGSNNDDSYGSSNKKKSSY 364

Query: 1309 YLNNYYNMIKSVDRDNY 1325
              NN  +   S + D+Y
Sbjct: 365  GSNNDDSYGSSNNNDSY 381

 Score = 17.3 bits (33), Expect = 4.0
 Identities = 9/32 (28%), Positives = 16/32 (50%)

Query: 311 NNEYDGCNFNDMLNNNCKSLNVHKSICLDKSN 342
           NN+  G N +D   ++ ++ N + S     SN
Sbjct: 377 NNDSYGSNNDDSYGSSNRNKNSYGSSNYGSSN 408

 Score = 16.5 bits (31), Expect = 6.9
 Identities = 7/25 (28%), Positives = 11/25 (44%)

Query: 289 NNNILEYKKEQKNYFISPQNIINNE 313
           NNN       Q +Y    +N+I  +
Sbjct: 15  NNNNDSGNNNQGDYVTKAENMIGED 39

 Score = 16.5 bits (31), Expect = 6.9
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 180 NNININDNE 188
           +N +INDN+
Sbjct: 65  SNTSINDND 73

Lambda     K      H
   0.313    0.130    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 6224
Number of extensions: 927
Number of successful extensions: 194
Number of sequences better than 10.0: 1
Number of HSP's gapped: 78
Number of HSP's successfully gapped: 69
Length of query: 1740
Length of database: 430
Length adjustment: 42
Effective length of query: 1698
Effective length of database: 388
Effective search space:   658824
Effective search space used:   658824
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 30 (16.5 bits)
S2: 30 (16.2 bits)