Query= PF10_0277 Pf Annotation|Plasmodium_falciparum_TIGR|(protein coding) hypothetical protein, conserved (315 letters)
>YKL172W EBP2 SGDID:S000001655, Chr XI from 125764-127047, Verified
           ORF, "Essential protein required for the maturation of
           25S rRNA and 60S ribosomal subunit assembly, localizes
           to the nucleolus; constituent of 66S pre-ribosomal
           particles"
          Length = 427

 Score = 51.2 bits (121), Expect = 4e-11
 Identities = 37/128 (28%), Positives = 61/128 (47%), Gaps = 3/128 (2%)

Query: 97  KKNNWIERLDITSTEYYYLKKTELFGISESREKQLQNITHMNVIQALQKLQELNIKFNRP 156
           KK+++ E   +TS         +++  +E RE      +   V+ A  +L+ L + F RP
Sbjct: 213 KKHSFQEHQSVTSETNTDEHIKDIYDDTE-RELAFYKQSLDAVLVARDELKRLKVPFKRP 271

Query: 157 YDFLADMLKSDIHMEKIRQKILKEHEQAEVREXXXXXXXXXXXXXXCGSQKIKSHKEALE 216
            D+ A+M+KSD HM+KI+ K+++E    + RE                 Q     K  LE
Sbjct: 272 LDYFAEMVKSDEHMDKIKGKLIEEASDKKAREEARRQRQLKKFGKQV--QNATLQKRQLE 329

Query: 217 KKQNLLKI 224
           K++ L KI
Sbjct: 330 KRETLEKI 337

 Score = 18.5 bits (36), Expect = 0.31
 Identities = 20/92 (21%), Positives = 36/92 (39%)

Query: 97  KKNNWIERLDITSTEYYYLKKTELFGISESREKQLQNITHMNVIQALQKLQELNIKFNRP 156
           KK+  +++ + T      LKK E        +K++   T     QAL K ++  +K    
Sbjct: 30  KKSQELKKEEPTIVTASNLKKLEKKEKKADVKKEVAADTEEYQSQALSKKEKRKLKKELK 89

Query: 157 YDFLADMLKSDIHMEKIRQKILKEHEQAEVRE 188
                D  ++  HM     +   + E+ E  E
Sbjct: 90  KMQEQDATEAQKHMSGDEDESGDDREEEEEEE 121

 Score = 16.9 bits (32), Expect = 0.90
 Identities = 5/16 (31%), Positives = 12/16 (75%)

Query: 206 QKIKSHKEALEKKQNL 221
           +++ SH++ +EK + L
Sbjct: 8   KELLSHQKEIEKAEKL 23

 Score = 15.4 bits (28), Expect = 2.6
 Identities = 11/54 (20%), Positives = 27/54 (50%), Gaps = 1/54 (1%)

Query: 134 ITHMNVIQALQKLQ-ELNIKFNRPYDFLADMLKSDIHMEKIRQKILKEHEQAEV 186
           ++H   I+  +KL+ +L  K ++        + +  +++K+ +K  K   + EV
Sbjct: 11  LSHQKEIEKAEKLENDLKKKKSQELKKEEPTIVTASNLKKLEKKEKKADVKKEV 64
Lambda     K      H
   0.315    0.132    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 237
Number of extensions: 15
Number of successful extensions: 8
Number of sequences better than 10.0: 1
Number of HSP's gapped: 5
Number of HSP's successfully gapped: 4
Length of query: 315
Length of database: 427
Length adjustment: 30
Effective length of query: 285
Effective length of database: 397
Effective search space:   113145
Effective search space used:   113145
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 23 (13.4 bits)
S2: 23 (13.5 bits)