>YOR243C PUS7 SGDID:S000005769, Chr XV from 792242-790212, reverse
           complement, Verified ORF, "Pseudouridine synthase,
           catalyzes pseudouridylation at position 35 in U2 snRNA,
           position 13 in cytoplasmic tRNAs, and position 35 in
           pre-tRNA(Tyr); Asp(256) mutation abolishes activity;
           conserved in archaea, some bacteria, and vertebrates"
          Length = 676

 Score = 90.5 bits (223), Expect = 3e-22
 Identities = 58/168 (34%), Positives = 87/168 (51%), Gaps = 12/168 (7%)

Query: 444 YLHFNLYKENKDICEILNKFKMNLSKKNTDISYCGIKDKRAITVQKFCIHKTNKYDIYNL 503
           ++HF L+KENKD  E +N     L   +  I Y G KD+RA+T Q+  I K    D  N 
Sbjct: 219 FIHFTLHKENKDTMEAVNVITKLLRVPSRVIRYAGTKDRRAVTCQRVSISKIG-LDRLNA 277

Query: 504 ISXXXXXXXXXXXVYISNLEYKRKKLSLGNLNGNHFKVIIRGV--HNNVKSNFHILS--- 558
           ++           + I N  +    L+LG+L GN F V+IR V   N+  S   I+S   
Sbjct: 278 LN------RTLKGMIIGNYNFSDASLNLGDLKGNEFVVVIRDVTTGNSEVSLEEIVSNGC 331

Query: 559 ENLRTKGFVNYYGHQRFGTKQIKNYEIGISILKRNYKHSLSYVIQNTE 606
           ++L   GF+NY+G QRFGT  I  + IG  +L  N+K +   ++ + +
Sbjct: 332 KSLSENGFINYFGMQRFGTFSISTHTIGRELLLSNWKKAAELILSDQD 379

 Score = 62.4 bits (150), Expect = 1e-13
 Identities = 66/264 (25%), Positives = 117/264 (44%), Gaps = 45/264 (17%)

Query: 733 AFMNLPKDIFSLFIHAIQSIVFNLLVSIRMKKFGLQIALGDLVEIYEQHHSGYXXXXXXX 792
           A M +P+++ ++++HA QS V+N + S R++  GL++ +GDLV       S         
Sbjct: 438 AIMKIPRNLRTMYVHAYQSYVWNSIASKRIELHGLKLVVGDLV----IDTSEKSPLISGI 493

Query: 793 XXXXXXXXXXXXMLYESKIIPITENNISLYNIYDVVLPLPGDKNIVLPPN--LKEEYIKV 850
                           +K +   + +   Y + DVVLP PG  +++ P N  LK+ Y+ +
Sbjct: 494 DDEDFDEDVREAQFIRAKAVTQEDIDSVKYTMEDVVLPSPG-FDVLYPSNEELKQLYVDI 552

Query: 851 LETINLTLEDFKSEKHFFNASGCYRKIVVKPYNFKSIFIKNELNDLNKIPIIKSDLYKLK 910
           L+  N+   + + +   F+ +G YR ++ KP   KS+  +    D     ++ +DL    
Sbjct: 553 LKADNMDPFNMRRKVRDFSLAGSYRTVIQKP---KSLEYRIIHYDDPSQQLVNTDL---- 605

Query: 911 NEDKENNTFIKEQLPNKTNQASSQIITEQQNVEDELIYVSNEQYHE-YLIKEIPDY-QTT 968
             D  NNT  KE                           S ++Y +  L + +PD     
Sbjct: 606 --DILNNTRAKE---------------------------SGQKYMKAKLDRYMPDKGGEK 636

Query: 969 SSIYLTCSLPKSSYITVALMELLK 992
           +++ L   L  S+Y T+AL EL+K
Sbjct: 637 TAVVLKFQLGTSAYATMALRELMK 660

 Score = 32.3 bits (72), Expect = 1e-04
 Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 3/53 (5%)

Query: 21  QLEGIYGKIKTIYEDFHVHEITKKNEILHL---NYVIDKNIIKNILQENEEKE 70
           +L G  G+IK  Y DF V+EI ++ +++HL    + + K   ++  + N EKE
Sbjct: 52  ELPGFRGQIKQRYTDFLVNEIDQEGKVIHLTDKGFKMPKKPQRSKEEVNAEKE 104

 Score = 23.5 bits (49), Expect = 0.052
 Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 10/65 (15%)

Query: 286 LKGTYKKSRYNKTEELEYIINQHFHNINKKKLDPSQEINESHLSDSYNNNNNVKTNEHIL 345
           L G+Y+ +   K + LEY I  +         DPSQ++  + L D  NN    ++ +  +
Sbjct: 572 LAGSYR-TVIQKPKSLEYRIIHYD--------DPSQQLVNTDL-DILNNTRAKESGQKYM 621

Query: 346 KARLN 350
           KA+L+
Sbjct: 622 KAKLD 626

Lambda     K      H
   0.315    0.134    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 1356
Number of extensions: 62
Number of successful extensions: 9
Number of sequences better than 10.0: 1
Number of HSP's gapped: 6
Number of HSP's successfully gapped: 6
Length of query: 993
Length of database: 676
Length adjustment: 41
Effective length of query: 952
Effective length of database: 635
Effective search space:   604520
Effective search space used:   604520
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 30 (16.5 bits)
S2: 30 (16.2 bits)