>YLR060W FRS1 SGDID:S000004050, Chr XII from 260980-262767, Verified
           ORF, "Beta subunit of cytoplasmic phenylalanyl-tRNA
           synthetase, forms a tetramer with Frs2p to generate the
           active enzyme; evolutionarily distant from mitochondrial
           phenylalanyl-tRNA synthetase based on protein sequence,
           but substrate binding is similar"
          Length = 595

 Score =  304 bits (779), Expect = 6e-87
 Identities = 191/635 (30%), Positives = 323/635 (50%), Gaps = 57/635 (8%)

Query: 1   MPTISVYEDDXXXXXXXXXXXXXXXDVCFDFGLEVDDIEYKNDKKI-----YKIEVPANR 55
           MPT+SV +                 ++CF+FG+E+D+   +   K       K+++ ANR
Sbjct: 1   MPTVSVNKQQLFDLLGKNYTSQEFDELCFEFGMEMDEDTTEEALKTGEEPELKLDISANR 60

Query: 56  YDLICVEGLCRALKNFMCKFDDIKYDISMNNYDICIKGNQYIKVDGSVDDRRGYVVCCVL 115
           YDL+C+EG+ ++L  ++ + +   Y +S        K    + +D S +  R +    VL
Sbjct: 61  YDLLCIEGISQSLNEYLERKERPDYKLS--------KPTTKLIIDKSTEQIRPFATAAVL 112

Query: 116 KNMNINDSVYNNIIEIQEKLHHNLGKKRSVLAIGIHDYDKIKFPLKYKFEKKEKINFIPL 175
           +N+ +N+  Y + I +Q+KLH NL + RS++A+G HD D I+ P  Y+    + I F+PL
Sbjct: 113 RNIKLNEKSYASFIALQDKLHANLCRNRSLVAMGTHDLDSIEGPFHYRALPPKDIKFVPL 172

Query: 176 NEKTNLNGMNLIDFY---SKNLNLKPYLKIIKDFDKYPIIVDSNEQILSLPPIINCDHTK 232
           N+     G  LI+FY    +  N+  Y+ II+D   +P+I+DS +++ SLPP+IN +H+K
Sbjct: 173 NQTQEFTGDKLIEFYKSPEQKNNIGRYVHIIEDSPVFPVIMDSKDRVCSLPPLINSEHSK 232

Query: 233 ISLNTKNVFIECTAIDRNKAQIALNILCSMLSEYCVPKYSIQSFVVIYENQDFSDDQNLK 292
           IS+NT+N+ I+ TA D+ KA+I LNIL +M S YC   ++++   ++ E+   S      
Sbjct: 233 ISVNTRNILIDITATDKTKAEIVLNILTTMFSRYCDEPFTVEPVEIVSEHNGQSR----- 287

Query: 293 KKETQFLYPIFENKSLTCNIDYVRKLSGISHITVHEVNNLLKRMMLSC--DIMDNNTFKV 350
                 L P F ++ +  +I Y+    G+   +  E+ + LK+M L       D +   V
Sbjct: 288 ------LAPNFNDRIMDVSIKYINSCLGLDQ-SADEIAHCLKKMSLHAVQSKEDKDILHV 340

Query: 351 TIPFYRSDIMHCCDIIEDIAIAYGYGNI-KYEPPQ----ICKKHSLNNCSELFRNVLVEC 405
            IP  R DI+H CDI+ED A+ YG+ N+ K E       I K   +N  S++FR    + 
Sbjct: 341 DIPVTRPDILHACDIMEDAAVGYGFNNLPKGEKLSNANFIAKPLPINKVSDIFRVASSQA 400

Query: 406 GYTEVMTNALLSRDENYNCMLRTHKSYDDPNINLDEYNPLAAPIQIKNSKTSEYEIIRTS 465
            + EV+   L S DEN+   LR   + D               +++ N KT EY+++RT+
Sbjct: 401 TWVEVLPLTLCSHDENFK-FLRQSDNGD-------------LAVKLANPKTLEYQVVRTT 446

Query: 466 LIVNLLKFVSANKHRELPLRFFEIGDVSYATYNQTDTNAVNKKYLSIIFSDKFTAGLEEL 525
           L+  +LK V  N+   LP++ FE GDV +   ++ +  A N+++ + I+  K  +G E +
Sbjct: 447 LLPGILKTVKENRKHSLPIKVFETGDVVFKD-DKLERKAYNERHWAAIYVGK-NSGFEII 504

Query: 526 HGVLEAILKEY--QLFSDYKIXXXXXXNISIRSDMYYKLIPKEDPSFLNERIVDIVLFPH 583
            G+L  I++ +  +  +DY              D      P      +            
Sbjct: 505 QGLLGKIMQTFRTEWIADYGAAASGRGYWIEEDDSVKTYFPGRGAKVMFRSKEG----AE 560

Query: 584 NLKFGVLGIIHPKVLENFSLDIPVSAIEINVETLL 618
             + G LG++HP+V+ NF +    S +E+N E  L
Sbjct: 561 PKQIGHLGVLHPEVMMNFDVPFAASFVEVNAEVFL 595

Lambda     K      H
   0.322    0.140    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 964
Number of extensions: 58
Number of successful extensions: 18
Number of sequences better than 10.0: 1
Number of HSP's gapped: 4
Number of HSP's successfully gapped: 3
Length of query: 623
Length of database: 595
Length adjustment: 37
Effective length of query: 586
Effective length of database: 558
Effective search space:   326988
Effective search space used:   326988
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 27 (15.4 bits)
S2: 27 (15.0 bits)