>YOL034W SMC5 SGDID:S000005394, Chr XV from 259924-263205, Verified
            ORF, "Structural maintenance of chromosomes (SMC)
            protein, interacts with Smc6p and Nse1p to form a large
            complex; S. pombe homolog forms a heterodimer with S.
            pombe Rad18p that is involved in DNA repair"
          Length = 1093

 Score = 77.8 bits (190), Expect = 5e-18
 Identities = 58/204 (28%), Positives = 106/204 (51%), Gaps = 20/204 (9%)

Query: 1009 HFNLEQVENKLKECIIQEKIYNNLDSNNNKCEEKYNILLLSIERHKENVQNKIKQIDNLK 1068
            +FNL  V++ L      +K+ + +   N+  +E    +L  +      +++ + Q     
Sbjct: 860  NFNLSFVQDVL------DKLESEIAMVNH--DESAVTILDQVTAELRELEHTVPQQSKDL 911

Query: 1069 ETISENEKQIHFILPQWSNQINEYIIFLNYNFEKFMNFINPEFYGKIDLIKKNDIYEKCE 1128
            ETI    K+ H +L     ++++ +  ++  F +  N +     G + L K  D Y + +
Sbjct: 912  ETIKAKLKEDHAVLEP---KLDDIVSKISARFARLFNNVGSA--GAVRLEKPKD-YAEWK 965

Query: 1129 LYIKVKFKKNAPFLLLSISHQSGGERSLTTMLYILSIQKLTKNGFYVLDELNQGLDHINE 1188
            + I VKF+ NAP   L    QSGGER+++T+LY++++Q+ T   F V+DE+NQG+D  NE
Sbjct: 966  IEIMVKFRDNAPLKKLDSHTQSGGERAVSTVLYMIALQEFTSAPFRVVDEINQGMDSRNE 1025

Query: 1189 QKIFQLL---SCLSNPIMYKQYFL 1209
            + + + +   +C  N     QYFL
Sbjct: 1026 RIVHKAMVENACAENT---SQYFL 1046

 Score = 71.2 bits (173), Expect = 5e-16
 Identities = 51/172 (29%), Positives = 83/172 (48%), Gaps = 13/172 (7%)

Query: 85  NLKKGAIIEMTLYNWMVFSGPITLRANKGINLIAAANASGKSSIACALVFGLGYNSNILS 144
           + + G+II++ L +++ ++       +  +N+I   N SGKS+  CA+  GL      + 
Sbjct: 36  SFQPGSIIKIRLQDFVTYT-LTEFNLSPSLNMIIGPNGSGKSTFVCAVCLGLAGKPEYIG 94

Query: 145 RNKELINFIKKGEKKSFIEITLK----------CDEEKKYICIKRIMNIINNKVESFWFV 194
           R+K++ +FIK G+  S IEITLK           D   + I I RI  I  +K  S + +
Sbjct: 95  RSKKVEDFIKNGQDVSKIEITLKNSPNVTDIEYIDARDETIKITRI--ITRSKRRSDYLI 152

Query: 195 XXXXXXXXXXXXXXXXFNLNLDNLITFMPQENVSKFSRLNPEELFECTLLAI 246
                            N+ LDNL  F+ QE V +F+RL   +L   T+ +I
Sbjct: 153 NDYQVSESVVKTLVAQLNIQLDNLCQFLSQERVEEFARLKSVKLLVETIRSI 204

 Score = 34.3 bits (77), Expect = 6e-05
 Identities = 33/139 (23%), Positives = 62/139 (44%), Gaps = 17/139 (12%)

Query: 481 NIKEKELQNDLKKISDENKKLLMKKYNLQSEYKSILDKLKKRKN-YKNIQEEKFLNSIEF 539
           N  +  + ++ +KI  EN+ + +K  N  ++ KS LD L  +K+ Y++          E 
Sbjct: 644 NFYQGSIMSNEQKIRIENEIINLK--NEYNDRKSTLDALSNQKSGYRH-------ELSEL 694

Query: 540 TLRERILNYKKNIKNIVETYNLLNKEYIENLKKKYDQTKLH-------NINEFNDEIVDE 592
             +   +N + +  N +     + K  IE L++K DQ K          I + +D+I   
Sbjct: 695 ASKNDDINREAHQLNEIRKKYTMRKSTIETLREKLDQLKREARKDVSQKIKDIDDQIQQL 754

Query: 593 LSKQNIIYGPLCKYIKCIK 611
           L KQ  +   +   +K +K
Sbjct: 755 LLKQRHLLSKMASSMKSLK 773

 Score = 26.9 bits (58), Expect = 0.010
 Identities = 11/38 (28%), Positives = 22/38 (57%)

Query: 317 IEHKKKQVINIKEHIESLIKEKDTHFNTLKYYLSELEK 354
           I+ K+K++IN +  I  LI E D   N + + +  +++
Sbjct: 401 IDIKRKEIINKEGEIRDLISEIDAKANAINHEMRSIQR 438

 Score = 23.5 bits (49), Expect = 0.11
 Identities = 21/84 (25%), Positives = 35/84 (41%), Gaps = 12/84 (14%)

Query: 994  KNELSQEEINTLDTIHFNLEQVENKLKECIIQEKIYNNLDSNNNKCEEKYNILLLSIERH 1053
            KNE +  + +TLD +        ++L E   +    N      N+  +KY +   +IE  
Sbjct: 667  KNEYNDRK-STLDALSNQKSGYRHELSELASKNDDINREAHQLNEIRKKYTMRKSTIETL 725

Query: 1054 KE-----------NVQNKIKQIDN 1066
            +E           +V  KIK ID+
Sbjct: 726  REKLDQLKREARKDVSQKIKDIDD 749

 Score = 22.3 bits (46), Expect = 0.24
 Identities = 30/137 (21%), Positives = 61/137 (44%), Gaps = 17/137 (12%)

Query: 473 LNDDNQYHNIKEKELQNDLKKIS-------DENKKLLMKKYNLQSEYKSILDKLKKRKNY 525
           L D   + N K K L+N +++++       DE  K   K   +  +  +I D++ K+KN 
Sbjct: 300 LKDKKPFANTK-KTLENQVEELTEKCSLKTDEFLKAKEKINEIFEKLNTIRDEVIKKKN- 357

Query: 526 KNIQEEKFLNSIEFTLRERILNYKKNI---KNIVETYNLLNKEYIENLKKKYDQTKLHNI 582
               + ++       L+  I++ K++    + I+   +L  K   E++  K  +  ++  
Sbjct: 358 ----QNEYYRGRTKKLQATIISTKEDFLRSQEILAQTHLPEKSVFEDIDIKRKEI-INKE 412

Query: 583 NEFNDEIVDELSKQNII 599
            E  D I +  +K N I
Sbjct: 413 GEIRDLISEIDAKANAI 429

 Score = 21.2 bits (43), Expect = 0.54
 Identities = 12/28 (42%), Positives = 19/28 (67%), Gaps = 1/28 (3%)

Query: 842 EFEKMKKEKNDEYNKIILERNEMNIKKK 869
           EF K K++ N+ + K+   R+E+ IKKK
Sbjct: 330 EFLKAKEKINEIFEKLNTIRDEV-IKKK 356

 Score = 20.8 bits (42), Expect = 0.71
 Identities = 12/42 (28%), Positives = 23/42 (54%), Gaps = 1/42 (2%)

Query: 846 MKKEKNDEYNKIILERNEMNIKKKKCTLLKNELIKIDENLDK 887
           +K +K     K  LE N++    +KC+L  +E +K  E +++
Sbjct: 300 LKDKKPFANTKKTLE-NQVEELTEKCSLKTDEFLKAKEKINE 340

 Score = 19.6 bits (39), Expect = 1.6
 Identities = 21/103 (20%), Positives = 40/103 (38%), Gaps = 4/103 (3%)

Query: 969  IEIEKNKLNSYIYDINELNGLLKIQKNELSQEEINTLDTIHFNLEQVENKLKECIIQEKI 1028
            ++  K KLN Y  +       L+    +  +   NT  T+     QVE   ++C ++   
Sbjct: 275  VKDHKEKLNIYKEEYERAKANLRAILKD-KKPFANTKKTLE---NQVEELTEKCSLKTDE 330

Query: 1029 YNNLDSNNNKCEEKYNILLLSIERHKENVQNKIKQIDNLKETI 1071
            +       N+  EK N +   + + K   +    +   L+ TI
Sbjct: 331  FLKAKEKINEIFEKLNTIRDEVIKKKNQNEYYRGRTKKLQATI 373

 Score = 19.6 bits (39), Expect = 1.6
 Identities = 9/23 (39%), Positives = 13/23 (56%)

Query: 855 NKIILERNEMNIKKKKCTLLKNE 877
           N+II  +NE N +K     L N+
Sbjct: 661 NEIINLKNEYNDRKSTLDALSNQ 683

 Score = 17.7 bits (34), Expect = 6.0
 Identities = 6/13 (46%), Positives = 9/13 (69%)

Query: 652 ITTNDKYSDMNKD 664
           +TT DK   +N+D
Sbjct: 447 LTTTDKIGILNQD 459

Lambda     K      H
   0.318    0.137    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 2958
Number of extensions: 147
Number of successful extensions: 16
Number of sequences better than 10.0: 1
Number of HSP's gapped: 13
Number of HSP's successfully gapped: 12
Length of query: 1268
Length of database: 1093
Length adjustment: 47
Effective length of query: 1221
Effective length of database: 1046
Effective search space:  1277166
Effective search space used:  1277166
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 33 (18.0 bits)
S2: 33 (17.3 bits)