>YNL061W NOP2 SGDID:S000005005, Chr XIV from 510541-512397, Verified
           ORF, "Probable RNA m(5)C methyltransferase, essential
           for processing and maturation of 27S pre-rRNA and large
           ribosomal subunit biogenesis; localized to the
           nucleolus; constituent of 66S pre-ribosomal particles"
          Length = 618

 Score =  229 bits (585), Expect = 2e-64
 Identities = 132/332 (39%), Positives = 195/332 (58%), Gaps = 7/332 (2%)

Query: 183 RSTIINELLFXXXXXXXXSKEMIKYLYYIFDIKELYLFLEINNMPKEIHLRTNTLKITRN 242
           R   ++ LL         +  + + L+ +F   E   F E N + + I +RTNTLK  R 
Sbjct: 224 RGEYVDRLLKDICEYFGYTPFLAEKLFNLFSPAEAMEFFEANEIARPITIRTNTLKTRRR 283

Query: 243 NLMKILKNQNVSVQEGESWNHVGITIKDVNTNVGSLNEYLYGYYIIQSSSSLMPVLELNI 302
           +L + L N+ V++Q   SW  VG+ I D    +G+  EYL G+YI+Q++SS +PV+ L+ 
Sbjct: 284 DLAQTLVNRGVNLQPIGSWTKVGLQIFDSQVPIGATPEYLAGHYILQAASSFLPVIALDP 343

Query: 303 QEDDMVLDMCAAPGGKCTFMCTLKKNRGVVYANDINKLRCKAIEAHASRMGINNLIVTCI 362
            E++ +LDM AAPGGK T++  + KN G V+AND NK R K++ A+  R+G  N IV   
Sbjct: 344 HENERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSRTKSLIANIHRLGCTNTIVCNY 403

Query: 363 DALKIQKHLTFQFDKILLDAPCSGTGVVNKNKTAR-RKTIKEIRDL--AQKQ--XXXXXX 417
           DA +  K +   FD+ILLDAPCSGTGV+ K+++ +  +T K+   +   QKQ        
Sbjct: 404 DAREFPK-VIGGFDRILLDAPCSGTGVIGKDQSVKVSRTEKDFIQIPHLQKQLLLSAIDS 462

Query: 418 XXXXXXXGGIVVYSTCSISVEENEQVINYILKKR-DVNLLPTNINIGDPGITQYRKKQFS 476
                  GG++VYSTCS++VEE+E VI+Y L+KR +V L+ T + IG    T YR K+F 
Sbjct: 463 VDCNSKHGGVIVYSTCSVAVEEDEAVIDYALRKRPNVKLVDTGLAIGKEAFTSYRGKKFH 522

Query: 477 SKISLCKRIYLHKHNHDNFFIAKLIKRSDAVF 508
             + L +R Y H +N D FF+AK  K   + F
Sbjct: 523 PSVKLARRYYPHTYNVDGFFVAKFQKIGPSSF 554

 Score = 17.7 bits (34), Expect = 1.6
 Identities = 9/23 (39%), Positives = 12/23 (52%)

Query: 439 ENEQVINYILKKRDVNLLPTNIN 461
           E+E+   YI K    NLL   +N
Sbjct: 586 EDEEDDKYIEKSVKNNLLKKGVN 608

 Score = 16.5 bits (31), Expect = 3.6
 Identities = 8/31 (25%), Positives = 16/31 (51%)

Query: 148 VYKNDKLMKNEDIEDRMKYLLILLNDTKKNN 178
           V + DK +   D+E+  K    L +D + ++
Sbjct: 66  VVEEDKDLPEVDLEELSKARKSLFDDEEDDD 96

 Score = 16.5 bits (31), Expect = 3.6
 Identities = 9/29 (31%), Positives = 16/29 (55%), Gaps = 1/29 (3%)

Query: 244 LMKILKNQNVSVQEGES-WNHVGITIKDV 271
           ++K+L+N      EG S   +V   +KD+
Sbjct: 207 IVKVLENFKTLGAEGRSRGEYVDRLLKDI 235

 Score = 15.4 bits (28), Expect = 8.0
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 238 KITRNNLMK 246
           K  +NNL+K
Sbjct: 596 KSVKNNLLK 604

Lambda     K      H
   0.316    0.133    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 688
Number of extensions: 34
Number of successful extensions: 10
Number of sequences better than 10.0: 1
Number of HSP's gapped: 5
Number of HSP's successfully gapped: 5
Length of query: 634
Length of database: 618
Length adjustment: 38
Effective length of query: 596
Effective length of database: 580
Effective search space:   345680
Effective search space used:   345680
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)