>YJR070C LIA1 SGDID:S000003831, Chr X from 570513-569536, reverse
           complement, Verified ORF, "Deoxyhypusine hydroxylase, a
           HEAT-repeat containing metalloenzyme that catalyses
           hypusine formation; binds to and is required for the
           modification of Hyp2p (eIF5A); complements S. pombe mmd1
           mutants defective in mitochondrial positioning"
          Length = 325

 Score = 76.3 bits (186), Expect = 1e-18
 Identities = 49/121 (40%), Positives = 68/121 (56%), Gaps = 4/121 (3%)

Query: 48  LKYLVNIKNDYIEKQMRALYECREVYKDDIDEVINILTYALKNNDSVLLRHEIAYVIGQI 107
           L+ L+N     + ++ RA++  R++     DE I  L     + +S L +HEIAYV GQI
Sbjct: 191 LQALLNDPKQPLFQRYRAMFRLRDI---GTDEAILALATGF-SAESSLFKHEIAYVFGQI 246

Query: 108 SNEKCNNILINLLSDENENIMVRHEAAEGLAAIGSESNIPVIKKYLNDSSVEVRETCELA 167
            +      LI +L  + E  MVRHEAAE L AI S   + V+K YLND    VRE+C +A
Sbjct: 247 GSPAAVPSLIEVLGRKEEAPMVRHEAAEALGAIASPEVVDVLKSYLNDEVDVVRESCIVA 306

Query: 168 L 168
           L
Sbjct: 307 L 307

 Score = 75.1 bits (183), Expect = 3e-18
 Identities = 42/120 (35%), Positives = 69/120 (57%), Gaps = 7/120 (5%)

Query: 59  IEKQMRALYECREVYKD------DIDEVINILTYALKNNDSVLLRHEIAYVIGQISNEKC 112
           +  + RAL+  + V ++      +  + I  +  +  N+ S LL+HE+AYV+GQ  N   
Sbjct: 34  LANRFRALFNLKTVAEEFATKPEEAKKAIEYIAESFVNDKSELLKHEVAYVLGQTKNLDA 93

Query: 113 NNILINLLSDENENIMVRHEAAEGLAAIGSESNIPVIKKYL-NDSSVEVRETCELALSSL 171
              L +++ D+N+  MVRHEAAE L A+G + ++  + K    D  V VRETCELA++ +
Sbjct: 94  APTLRHVMLDQNQEPMVRHEAAEALGALGDKDSLDDLNKAAKEDPHVAVRETCELAINRI 153

 Score = 72.8 bits (177), Expect = 1e-17
 Identities = 49/136 (36%), Positives = 68/136 (50%), Gaps = 15/136 (11%)

Query: 271 LNNEALALKNRYEALFLLRDMETDTSLNALGEALVKDKSSAIFRHELAFVLGQVLHLNSL 330
           LN+    L  RY A+F LRD+ TD ++ AL      +  S++F+HE+A+V GQ+    ++
Sbjct: 195 LNDPKQPLFQRYRAMFRLRDIGTDEAILALATGFSAE--SSLFKHEIAYVFGQIGSPAAV 252

Query: 331 KYLLSSLTNVSEHEMVRHEVXXXXXXXXXXXXXXDEYKIIQEQIIDTLKKYSKDECVVVA 390
             L+  L    E  MVRHE                   I   +++D LK Y  DE  VV 
Sbjct: 253 PSLIEVLGRKEEAPMVRHEAAEALGA------------IASPEVVDVLKSYLNDEVDVVR 300

Query: 391 ESCLVGLD-YISENLN 405
           ESC+V LD Y  EN N
Sbjct: 301 ESCIVALDMYDYENSN 316

 Score = 47.4 bits (111), Expect = 6e-10
 Identities = 40/164 (24%), Positives = 72/164 (43%), Gaps = 32/164 (19%)

Query: 258 SNNKKHVNDLIRDLNNEAL-----------ALKNRYEALFLLRDM---------ETDTSL 297
           +N +KH  + + +   E L            L NR+ ALF L+ +         E   ++
Sbjct: 3   TNFEKHFQENVDECTLEQLRDILVNKSGKTVLANRFRALFNLKTVAEEFATKPEEAKKAI 62

Query: 298 NALGEALVKDKSSAIFRHELAFVLGQVLHLNSLKYLLSSLTNVSEHEMVRHEVXXXXXXX 357
             + E+ V DKS  + +HE+A+VLGQ  +L++   L   + + ++  MVRHE        
Sbjct: 63  EYIAESFVNDKSE-LLKHEVAYVLGQTKNLDAAPTLRHVMLDQNQEPMVRHEAAEALGAL 121

Query: 358 XXXXXXXDEYKIIQEQIIDTLKKYSKDECVVVAESCLVGLDYIS 401
                        ++ + D  K   +D  V V E+C + ++ I+
Sbjct: 122 GD-----------KDSLDDLNKAAKEDPHVAVRETCELAINRIN 154

 Score = 19.6 bits (39), Expect = 0.14
 Identities = 24/140 (17%), Positives = 53/140 (37%), Gaps = 34/140 (24%)

Query: 45  EFILKYLVNIKNDYIEKQMRALYECREVYKDDIDEVINILTYALKNNDSVLLRHEIAYVI 104
           E+I +  VN K++ ++ ++  +    +    ++D    +    L  N   ++RHE A  +
Sbjct: 63  EYIAESFVNDKSELLKHEVAYVLGQTK----NLDAAPTLRHVMLDQNQEPMVRHEAAEAL 118

Query: 105 GQISNEKCNNILINLLSDENENIMVRHEAAEGLAAIG----------------------- 141
           G + ++   + L N  + E+ ++ VR      +  I                        
Sbjct: 119 GALGDKDSLDDL-NKAAKEDPHVAVRETCELAINRINWTHGGAKDKENLQQSLYSSIDPA 177

Query: 142 ------SESNIPVIKKYLND 155
                  ++ IP ++  LND
Sbjct: 178 PPLPLEKDATIPELQALLND 197

Lambda     K      H
   0.315    0.133    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 368
Number of extensions: 18
Number of successful extensions: 15
Number of sequences better than 10.0: 1
Number of HSP's gapped: 5
Number of HSP's successfully gapped: 5
Length of query: 411
Length of database: 325
Length adjustment: 30
Effective length of query: 381
Effective length of database: 295
Effective search space:   112395
Effective search space used:   112395
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 23 (13.4 bits)
S2: 23 (13.5 bits)