>YBL068W PRS4 SGDID:S000000164, Chr II from 92412-93395, Verified
           ORF, "5-phospho-ribosyl-1(alpha)-pyrophosphate
           synthetase, involved in nucleotide, histidine, and
           tryptophan biosynthesis; one of a five related enzymes,
           which are active as heteromultimeric complexes"
          Length = 327

 Score =  218 bits (555), Expect = 2e-61
 Identities = 129/318 (40%), Positives = 188/318 (59%), Gaps = 15/318 (4%)

Query: 120 LFSGTSNPLLSKNVADHLGTSLGRVNLKRFADGEVSMQFLESIRGKDVYIIQPTC--PPV 177
           L +G S+P L++ ++  LG  L +V + ++++ E S+   ES+R +DVYIIQ       +
Sbjct: 16  LLAGNSHPDLAEQISKKLGIPLSKVGVYQYSNKETSVTIGESLRDEDVYIIQTGIGEQEI 75

Query: 178 NENLIELLLMISTCRRASAKKITAVIPYYGYARQDRKLSSRVPISAADVARMIEAMGVDR 237
           N+ L+ELL++I  C+ ASA+KIT VIP + YARQD+K  SR PI+A  VA +++  G D 
Sbjct: 76  NDFLMELLILIHACQIASARKITTVIPNFPYARQDKKDKSRAPITAKLVANLLQTAGADH 135

Query: 238 VVAIDLHSGQIQGFFGPRVPVDNLEAQLIGLDYF--TKKDLYKPVIVSPDAGGVYRARKF 295
           V+ +DLH+ QIQGFF   +PVDNL A+   L+Y    K D    ++VSPDAGG  R    
Sbjct: 136 VITMDLHASQIQGFF--HIPVDNLYAEPSVLNYIRARKTDFDNAILVSPDAGGAKRVAAL 193

Query: 296 QDGLNHRGIGDCGIAMLIKQRTKPNEIEKMDLVGNXXXXXXXXXXXXXXTSGTLCEAAKQ 355
            D L      D   A++ K+R K NE+ KM LVG+              T GTL +A   
Sbjct: 194 ADKL------DLNFALIHKERQKANEVSKMVLVGDVTNKSCLLVDDMADTCGTLVKACDT 247

Query: 356 LKKHGARRVFAFATHGLFSGPAIDRIEKSPLEEVVVTDTVKSNKNIDSCKKITKLSVSVL 415
           L +HGA+ V A  THG+FSG A +++  S L  +V T+TV  + ++    +I    +S  
Sbjct: 248 LMEHGAKEVIAIVTHGIFSGSAREKLRNSRLSRIVCTNTVPVDLDLPIADQI---DISPT 304

Query: 416 VADAIRRIHQKESLNDLF 433
            A+AIRR+H  ES++ LF
Sbjct: 305 FAEAIRRLHNGESVSYLF 322

 Score = 17.3 bits (33), Expect = 0.74
 Identities = 34/159 (21%), Positives = 60/159 (37%), Gaps = 22/159 (13%)

Query: 116 ENAILFSGTSNPLLSKNVA---DHLGTSLGRVNLKRFADGEVS-MQFLESIRGKDVYIIQ 171
           +NAIL S  +    +K VA   D L  +   ++ +R    EVS M  +  +  K   ++ 
Sbjct: 175 DNAILVSPDAGG--AKRVAALADKLDLNFALIHKERQKANEVSKMVLVGDVTNKSCLLVD 232

Query: 172 PTCPPVNENLIELLLMISTCRRASAKKITAVIP---YYGYARQDRKLS--------SRVP 220
                       L+    T     AK++ A++    + G AR+  + S        + VP
Sbjct: 233 DMADTCGT----LVKACDTLMEHGAKEVIAIVTHGIFSGSAREKLRNSRLSRIVCTNTVP 288

Query: 221 ISA-ADVARMIEAMGVDRVVAIDLHSGQIQGFFGPRVPV 258
           +     +A  I+           LH+G+   +     PV
Sbjct: 289 VDLDLPIADQIDISPTFAEAIRRLHNGESVSYLFTHAPV 327

Lambda     K      H
   0.320    0.136    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 307
Number of extensions: 16
Number of successful extensions: 9
Number of sequences better than 10.0: 1
Number of HSP's gapped: 2
Number of HSP's successfully gapped: 2
Length of query: 437
Length of database: 327
Length adjustment: 30
Effective length of query: 407
Effective length of database: 297
Effective search space:   120879
Effective search space used:   120879
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 24 (14.0 bits)
S2: 24 (13.9 bits)