>YER099C PRS2 SGDID:S000000901, Chr V from 359057-358101, reverse
           complement, Verified ORF,
           "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase,
           involved in nucleotide, histidine, and tryptophan
           biosynthesis; one of a five related enzymes, which are
           active as heteromultimeric complexes"
          Length = 318

 Score =  221 bits (563), Expect = 3e-62
 Identities = 128/317 (40%), Positives = 190/317 (59%), Gaps = 14/317 (4%)

Query: 120 LFSGTSNPLLSKNVADHLGTSLGRVNLKRFADGEVSMQFLESIRGKDVYIIQPTCPP--V 177
           L +G S+P L++ ++  LG  L +V + ++++ E S+   ESIR +DVYIIQ       +
Sbjct: 8   LLAGNSHPGLAELISQRLGVPLSKVGVYQYSNKETSVTIGESIRDEDVYIIQTGYGEHEI 67

Query: 178 NENLIELLLMISTCRRASAKKITAVIPYYGYARQDRKLSSRVPISAADVARMIEAMGVDR 237
           N+ L+ELL++I  C+ AS ++ITAVIP + YARQD+K  SR PI+A  +A ++E  G D 
Sbjct: 68  NDFLMELLILIHACKTASVRRITAVIPNFPYARQDKKDKSRAPITAKLIANLLETAGCDH 127

Query: 238 VVAIDLHSGQIQGFFGPRVPVDNLEAQLIGLDYF-TKKDLYKPVIVSPDAGGVYRARKFQ 296
           V+ +DLH+ QIQGFF   +PVDNL  +   L+Y  TK D    ++VSPDAGG  R     
Sbjct: 128 VITMDLHASQIQGFF--HIPVDNLYGEPSVLNYIRTKTDFNNAILVSPDAGGAKRVASLA 185

Query: 297 DGLNHRGIGDCGIAMLIKQRTKPNEIEKMDLVGNXXXXXXXXXXXXXXTSGTLCEAAKQL 356
           D L      D   A++ K+R K NE+ +M LVG+              T GTL +A   L
Sbjct: 186 DKL------DMNFALIHKERQKANEVSRMLLVGDVAGKSCLLIDDMADTCGTLVKACDTL 239

Query: 357 KKHGARRVFAFATHGLFSGPAIDRIEKSPLEEVVVTDTVKSNKNIDSCKKITKLSVSVLV 416
             HGA+ V A  THG+FSG A +++  S L  +V T+TV  + ++D    + ++ +S  +
Sbjct: 240 MDHGAKEVIAIVTHGIFSGSAREKLINSRLSRIVCTNTVPVDLDLDI---VDQVDISPTI 296

Query: 417 ADAIRRIHQKESLNDLF 433
           A+AIRR+H  ES++ LF
Sbjct: 297 AEAIRRLHNGESVSYLF 313

 Score = 20.4 bits (41), Expect = 0.085
 Identities = 26/140 (18%), Positives = 55/140 (39%), Gaps = 17/140 (12%)

Query: 132 NVADHLGTSLGRVNLKRFADGEVS-MQFLESIRGKDVYIIQPTCPPVNENLIELLLMIST 190
           ++AD L  +   ++ +R    EVS M  +  + GK   +I             L+    T
Sbjct: 183 SLADKLDMNFALIHKERQKANEVSRMLLVGDVAGKSCLLIDDMADTCGT----LVKACDT 238

Query: 191 CRRASAKKITAVIPY--YGYARQDRKLSSR---------VPISA-ADVARMIEAMGVDRV 238
                AK++ A++ +  +  + +++ ++SR         VP+    D+   ++       
Sbjct: 239 LMDHGAKEVIAIVTHGIFSGSAREKLINSRLSRIVCTNTVPVDLDLDIVDQVDISPTIAE 298

Query: 239 VAIDLHSGQIQGFFGPRVPV 258
               LH+G+   +     PV
Sbjct: 299 AIRRLHNGESVSYLFTHAPV 318

Lambda     K      H
   0.320    0.136    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 292
Number of extensions: 13
Number of successful extensions: 8
Number of sequences better than 10.0: 1
Number of HSP's gapped: 2
Number of HSP's successfully gapped: 2
Length of query: 437
Length of database: 318
Length adjustment: 30
Effective length of query: 407
Effective length of database: 288
Effective search space:   117216
Effective search space used:   117216
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 24 (14.0 bits)
S2: 24 (13.9 bits)