>YDR037W KRS1 SGDID:S000002444, Chr IV from 525436-527211, Verified
           ORF, "Lysyl-tRNA synthetase; also identified as a
           negative regulator of general control of amino acid
           biosynthesis "
          Length = 591

 Score =  483 bits (1243), Expect = e-141
 Identities = 247/514 (48%), Positives = 355/514 (69%), Gaps = 13/514 (2%)

Query: 78  VDPRLYFENRSKFIQD-QKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNIT 136
           +DP  YFE RS+ IQ+ +K    NPYPHKF  +IS PEF+ KY  L  GE L +  ++I 
Sbjct: 68  LDPSQYFETRSRQIQELRKTHEPNPYPHKFHVSISNPEFLAKYAHLKKGETLPEEKVSIA 127

Query: 137 GRIMRVSASGQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFP 196
           GRI     SG KL+F+ L GDG ++Q+++    +  +  ++ + +D ++RGDIVG+ G+ 
Sbjct: 128 GRIHAKRESGSKLKFYVLHGDGVEVQLMSQLQDYC-DPDSYEKDHDLLKRGDIVGVEGYV 186

Query: 197 GKSK-----KGELSIFPKETILLSACLHMLPMK-YGLKDTEIRYRQRYLDLLINESSRHT 250
           G+++     +GE+S+F     LL+ CLHMLP   +G KD E RYR+RYLDL++N+ +R+ 
Sbjct: 187 GRTQPKKGGEGEVSVFVSRVQLLTPCLHMLPADHFGFKDQETRYRKRYLDLIMNKDARNR 246

Query: 251 FVTRTKIINFLRNFLNERGFFEVETPMMNLIAGGANARPFITHHNDLDLDLYLRIATELP 310
           F+TR++II ++R FL++R F EVETPMMN+IAGGA A+PFITHHNDLD+D+Y+RIA EL 
Sbjct: 247 FITRSEIIRYIRRFLDQRKFIEVETPMMNVIAGGATAKPFITHHNDLDMDMYMRIAPELF 306

Query: 311 LKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVY 370
           LK L+VGG+D+VYEIG+ FRNEGID THNPEFT+CEFY AYAD  DL+  +E  FS++V 
Sbjct: 307 LKQLVVGGLDRVYEIGRQFRNEGIDMTHNPEFTTCEFYQAYADVYDLMDMTELMFSEMVK 366

Query: 371 HLFGTYKISYNKDGPE-NQPIEIDFTPPYPKVSIVEEIEKVTNTILE--QPFDSNETIEK 427
            + G+Y I Y+ D  +  + +E++F+ P+ +++++EE+EKV N          + ET E 
Sbjct: 367 EITGSYIIKYHPDPADPAKELELNFSRPWKRINMIEELEKVFNVKFPSGDQLHTAETGEF 426

Query: 428 MINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPG 487
           +  I+ ++K+E P P T A++LD+L     +   N  P FI  HPQ+MSPLAKY R +PG
Sbjct: 427 LKKILVDNKLECPPPLTNARMLDKLVGELEDTCIN--PTFIFGHPQMMSPLAKYSRDQPG 484

Query: 488 LTERLEMFICGKEVLNAYTELNDPFKQKECFKLQQKDREKGDTEAAQLDSAFCTSLEYXX 547
           L ER E+F+  KE+ NAYTELNDPF Q+  F+ Q + +++GD EA  +D  FC +LEY  
Sbjct: 485 LCERFEVFVATKEICNAYTELNDPFDQRARFEEQARQKDQGDDEAQLVDETFCNALEYGL 544

Query: 548 XXXXXXXXXIDRITMFLTNKNSIKDVILFPTMRP 581
                    IDR+ MFLT+ N+I++V+LFPT++P
Sbjct: 545 PPTGGWGCGIDRLAMFLTDSNTIREVLLFPTLKP 578

 Score = 15.8 bits (29), Expect = 5.4
 Identities = 6/12 (50%), Positives = 7/12 (58%)

Query: 332 EGIDNTHNPEFT 343
           EG+ N H  E T
Sbjct: 12  EGVANLHLDEAT 23

Lambda     K      H
   0.320    0.139    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 892
Number of extensions: 34
Number of successful extensions: 11
Number of sequences better than 10.0: 1
Number of HSP's gapped: 2
Number of HSP's successfully gapped: 2
Length of query: 583
Length of database: 591
Length adjustment: 37
Effective length of query: 546
Effective length of database: 554
Effective search space:   302484
Effective search space used:   302484
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 27 (15.3 bits)
S2: 27 (15.0 bits)