>YOR335C ALA1 SGDID:S000005862, Chr XV from 949106-946230, reverse
            complement, Verified ORF, "Cytoplasmic alanyl-tRNA
            synthetase, required for protein synthesis; point
            mutation (cdc64-1 allele) causes cell cycle arrest at G1;
            lethality of null mutation is functionally complemented
            by human homolog"
          Length = 958

 Score =  615 bits (1585), Expect = e-180
 Identities = 385/1036 (37%), Positives = 551/1036 (53%), Gaps = 108/1036 (10%)

Query: 384  GQKKYMSAEEVRNNFINYFHKKNHTIIESSSVVPYNDNTLLFTNAGMNQFKKIFLGNADK 443
            G K+  +A  VRN F++YF  K H  ++SS VVP++D TLLF NAGMNQ+K IFLG  D 
Sbjct: 4    GDKQKWTATNVRNTFLDYFKSKEHKFVKSSPVVPFDDPTLLFANAGMNQYKPIFLGTVDP 63

Query: 444  NSDLGKLKRAVDTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGNWSFGDYFKEESISFAW 503
             SD   LKRA ++QKCIRAGGKHNDL+DVGKD YHHTFFEMLGNWSFGDYFK+E+I+++W
Sbjct: 64   ASDFYTLKRAYNSQKCIRAGGKHNDLEDVGKDSYHHTFFEMLGNWSFGDYFKKEAITYSW 123

Query: 504  DLLTNVYKINPDRLYVTYFGGDENLSTCPADHETKKIWMKY-ISEDRILPFGLKENFWEM 562
             LLT VY I  DRLYVTYF GDE L   P D E +++W    + +D ILP   K+NFWEM
Sbjct: 124  TLLTEVYGIPKDRLYVTYFEGDEKLGLEP-DTEARELWKNVGVPDDHILPGNAKDNFWEM 182

Query: 563  AETGPCGPCSEIHYDRIGNRDASSLVNKDDPSVLEIWNIVFMQYNKDENKNMNKLPFPCI 622
             + GPCGPCSEIHYDRIG R+A+SLVN DDP VLE+WN+VF+Q+N++++ ++  LP   I
Sbjct: 183  GDQGPCGPCSEIHYDRIGGRNAASLVNMDDPDVLEVWNLVFIQFNREQDGSLKPLPAKHI 242

Query: 623  DTGMGLERITSILQNVDSNYDTDLFQPIFKQIKELFPYLPNYEGKINEQDVDKIDTAYRV 682
            DTGMG ER+ S+LQ+V SNYDTD+F P+F++I+E+    P Y G   E D D IDTAYRV
Sbjct: 243  DTGMGFERLVSVLQDVRSNYDTDVFTPLFERIQEITSVRP-YSGNFGENDKDGIDTAYRV 301

Query: 683  ISDHIRCVTVAISDGCLPSNEGRNYVXXXXXXXXXXFGKQVFNIKSNVLWFYKLVDSVCF 742
            ++DH+R +T A++DG +P+NEGR YV          + ++  N      +F  L  ++  
Sbjct: 302  LADHVRTLTFALADGGVPNNEGRGYVLRRILRRGARYARKYMNYPIG-NFFSTLAPTLIS 360

Query: 743  ILGNTFKDLQNPDKINFIKNTIKQEEMVFNKTLEKGVEQF--HXXXXXXXXXXXFSGKDA 800
             + + F +L       F+   + +EE  F KTL++G   F  +             GK  
Sbjct: 361  QVQDIFPELAKDPA--FLFEILDEEEASFAKTLDRGERLFEKYASAASKTESKTLDGKQV 418

Query: 801  FDLYTSFGFPIDLIQIMCEEKSFNLDLQEFNDLFKKHQLVSDTNNFKINKFFDIPVEKSH 860
            + LY ++GFP+DL ++M EE+   +D   F    ++    S     K     D+     H
Sbjct: 419  WRLYDTYGFPVDLTELMAEEQGLKIDGPGFEKAKQESYEASKRGGKKDQS--DLIKLNVH 476

Query: 861  ELKNVHN--INPTVDHFKYEWNNNCANDGDNKDIKFETYVQVIYDGNNFLDNFTLPSNND 918
            EL  +++  +  T D FKY   N             E  +  ++DG NF+D  T P    
Sbjct: 477  ELSELNDAKVPKTNDEFKYGSAN------------VEGTILKLHDGTNFVDEITEPGKK- 523

Query: 919  EQVLXXXXXXXXXXXXYALILKETNFYYENGGQIYDTG-IIQNDNMKFQVLNVQKINEYV 977
                            Y +IL +T FY E GGQ YDTG I+ +D  +F V NVQ  N +V
Sbjct: 524  ----------------YGIILDKTCFYAEQGGQEYDTGKIVIDDAAEFNVENVQLYNGFV 567

Query: 978  LHIGVFLKGYVSKNDKVQTIVDFDRRKLVACNHTATHMLNFMLRKVLTEKYTNSGKSSKT 1037
             H G   +G +S  DK+    D  RR  +  NHT TH+LNF L++ L             
Sbjct: 568  FHTGSLEEGKLSVGDKIIASFDELRRFPIKNNHTGTHILNFALKETL------------- 614

Query: 1038 HEGNNEKHEMXXXXXXXXXXXXXXXXXXGFSIFTCEQKGSLVDDEKLRFDFSFIENINID 1097
              GN+                              +QKGSLV  EKLRFDFS  + ++ +
Sbjct: 615  --GND-----------------------------VDQKGSLVAPEKLRFDFSHKKAVSNE 643

Query: 1098 AITXXXXXXXXXXXXXXXVTVKTMDLDESKKIKGIRAIFEEDYADKVNVVFINKDVNNIL 1157
             +                V  K + LD +K I G+RA+F E Y D V VV + K +  +L
Sbjct: 644  ELKKVEDICNEQIKENLQVFYKEIPLDLAKSIDGVRAVFGETYPDPVRVVSVGKPIEELL 703

Query: 1158 NNMNIDYTYLHSIELCGGTHIGNTKLIRKFLVTSEESIGKGIYRITAVTNKKADEIEKTF 1217
             N   +    +SIE CGGTH+  T  I+ F++  E  I KGI RI AVT  +A E ++  
Sbjct: 704  ANPANEEWTKYSIEFCGGTHVNKTGDIKYFVILEESGIAKGIRRIVAVTGTEAFEAQR-- 761

Query: 1218 NDLYDKYKHVLQEPNENKLADVQNYKRTLKE------NKFLPYIKKYHILQELEQIEKTI 1271
              L +++   L   ++   + ++  K  LKE         +  I K  + Q+  +IEK +
Sbjct: 762  --LAEQFAADLDAADKLPFSPIKEKK--LKELGVKLGQLSISVITKNELKQKFNKIEKAV 817

Query: 1272 VEKTKNMQKELFNKATNIGKDYAVQDKNNILLDIKFFDEIKGNQKVLEKIVQSYSKNN-- 1329
             ++ K+  K+   +  +  K +   ++N   L +KF D I  N K + + + +Y K+N  
Sbjct: 818  KDEVKSRAKKENKQTLDEVKTFFETNENAPYL-VKFID-ISPNAKAITEAI-NYMKSNDS 874

Query: 1330 -KNLSYFFIICD--ENNTYCVLEVKEALKNKNVQADLFMKEIMKSVLGHSGGSKNKAFGS 1386
             K+ S + +  +  E        +  A   K +      K++  S++G   G K   F  
Sbjct: 875  VKDKSIYLLAGNDPEGRVAHGCYISNAALAKGIDGSALAKKV-SSIIGGKAGGKGNVFQG 933

Query: 1387 VEKDKGMVIKEHAEEM 1402
            +  DK   IK+  +++
Sbjct: 934  M-GDKPAAIKDAVDDL 948

 Score = 18.9 bits (37), Expect = 2.6
 Identities = 8/21 (38%), Positives = 10/21 (47%)

Query: 1236 LADVQNYKRTLKENKFLPYIK 1256
            + D Q +  T   N FL Y K
Sbjct: 3    IGDKQKWTATNVRNTFLDYFK 23

 Score = 18.1 bits (35), Expect = 4.4
 Identities = 7/10 (70%), Positives = 8/10 (80%)

Query: 264 TKNNLKEKKN 273
           TKN LK+K N
Sbjct: 802 TKNELKQKFN 811

Lambda     K      H
   0.319    0.137    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 3222
Number of extensions: 172
Number of successful extensions: 15
Number of sequences better than 10.0: 1
Number of HSP's gapped: 4
Number of HSP's successfully gapped: 4
Length of query: 1408
Length of database: 958
Length adjustment: 47
Effective length of query: 1361
Effective length of database: 911
Effective search space:  1239871
Effective search space used:  1239871
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 32 (17.6 bits)
S2: 32 (16.9 bits)