>YOL090W MSH2 SGDID:S000005450, Chr XV from 147382-150276, Verified
           ORF, "Protein that forms heterodimers, with Msh3p and
           Msh6p, that bind to DNA mismatches to initiate the
           mismatch repair process; contains a Walker ATP-binding
           motif required for repair activity; Msh2p-Msh6p binds to
           and hydrolyzes ATP"
          Length = 964

 Score =  405 bits (1042), Expect = e-117
 Identities = 253/788 (32%), Positives = 425/788 (53%), Gaps = 57/788 (7%)

Query: 28  LGVCFYNYLKYEFLMTEFIDNGHFTALESLFIQKRPHKCFF----NSTNDLVDDERLLNL 83
           +GV F +   Y+  M + +DN  ++ LES  IQ    +C      +++N   + ++++N+
Sbjct: 157 IGVAFIDTTAYKVGMLDIVDNEVYSNLESFLIQLGVKECLVQDLTSNSNSNAEMQKVINV 216

Query: 84  FKICNVQAIPLEKKKYDATNLKDELKLIISHNDDVRNYDKHLELE-NACKCLMVLINYLK 142
              C      L+  ++   +++ +L  ++  +  +    K+ +L   AC  L   I YL+
Sbjct: 217 IDRCGCVVTLLKNSEFSEKDVELDLTKLLGDDLALSLPQKYSKLSMGACNAL---IGYLQ 273

Query: 143 LKENQDIHNQCKINIHNMDLYMRLDKAAISALNILPNKKNIHSYNNN------------- 189
           L   QD   + ++  H +  +M+LD +AI ALN+ P        +NN             
Sbjct: 274 LLSEQDQVGKYELVEHKLKEFMKLDASAIKALNLFPQGPQNPFGSNNLAVSGFTSAGNSG 333

Query: 190 --TSLLKFLDKCNTTIGSKKLVSWLTQPLTNVAEINKRLNIVEFFIKEDDARNVIFCNYL 247
             TSL + L+ C T  G + L  WL QPLTN+ EINKR ++V++ I + + R ++   YL
Sbjct: 334 KVTSLFQLLNHCKTNAGVRLLNEWLKQPLTNIDEINKRHDLVDYLIDQIELRQMLTSEYL 393

Query: 248 KRIPELDKLNHYLKEINQNNEIR-VNSKYNEEMILKDIVKMYYSILDFKQIYFTLKPIQG 306
             IP++ +L    K++N+   +  V   Y     + +IV+++ S L+         P + 
Sbjct: 394 PMIPDIRRLT---KKLNKRGNLEDVLKIYQFSKRIPEIVQVFTSFLEDDS------PTEP 444

Query: 307 KNKETIDEIIINPLRDILNKFSKLLDMIEITIDLEEVQENKVYLISTSFDNELEIIANEK 366
            N E +  + + PL   +   SK  +M+E T+DL+  +EN  ++I   F+ EL  I ++ 
Sbjct: 445 VN-ELVRSVWLAPLSHHVEPLSKFEEMVETTVDLDAYEENNEFMIKVEFNEELGKIRSKL 503

Query: 367 NALMXXXXXXXXXXXXXIFADKYDRTYKRANREDIRLVDCNTNVFLFRVTKKDCGLVQQD 426
           + L              +  D  D+  K  N         + + +  R+T+ D   +++ 
Sbjct: 504 DTLRDEIHSIHLDSAEDLGFDP-DKKLKLENH--------HLHGWCMRLTRNDAKELRKH 554

Query: 427 KKKYMTVRMNKNEFLFTTNTLKNLCKQYDHCLNIYNTLQSEIINKTICAVSTYTPVIEKF 486
           KK Y+ +   K    F+T  LK++  + +     Y+  QS ++ + I    TYTPV EK 
Sbjct: 555 KK-YIELSTVKAGIFFSTKQLKSIANETNILQKEYDKQQSALVREIINITLTYTPVFEKL 613

Query: 487 IDLVSTLDVLISFSVVCHNSPFPYVRPVI--VDHGENVIMRKSRHPLLELQYNLNNFIPN 544
             +++ LDV+ SF+     +P PY+RP +  +D      +  SRHP+LE+Q +++ FI N
Sbjct: 614 SLVLAHLDVIASFAHTSSYAPIPYIRPKLHPMDSERRTHLISSRHPVLEMQDDIS-FISN 672

Query: 545 DIHMNKKNSRLIIVTGPNMGGKSTYIRQTAIICILAQIGMFVPCDFCEVPIFTQIMCRVG 604
           D+ +       +I+TGPNMGGKSTYIRQ  +I ++AQIG FVPC+  E+ I   I+CRVG
Sbjct: 673 DVTLESGKGDFLIITGPNMGGKSTYIRQVGVISLMAQIGCFVPCEEAEIAIVDAILCRVG 732

Query: 605 ASDFQLKGISTFLSEMIEAAAIVKNADQNSFIIVDELGRGTSTYEGLGISWSIGKYILDN 664
           A D QLKG+STF+ E++E A+I+KNA +NS IIVDELGRGTSTY+G G++W+I ++I   
Sbjct: 733 AGDSQLKGVSTFMVEILETASILKNASKNSLIIVDELGRGTSTYDGFGLAWAIAEHIASK 792

Query: 665 IKCFCLFATHFHEMSNIAYQCEGVINRHVETTIDKEKKK-------ICFLYEIKDGASNK 717
           I CF LFATHFHE++ ++ +   V N HV   I+K  K+       I  LY+++ G S++
Sbjct: 793 IGCFALFATHFHELTELSEKLPNVKNMHVVAHIEKNLKEQKHDDEDITLLYKVEPGISDQ 852

Query: 718 SYGVNVAEIAKLPKEVIQKAYEKVEELE--SAENKYYLKEKLNIDTSASADENYKMKISN 775
           S+G++VAE+ + P+++++ A  K  EL+     N+   K KL++      +   K  +  
Sbjct: 853 SFGIHVAEVVQFPEKIVKMAKRKANELDDLKTNNEDLKKAKLSLQEVNEGNIRLKALLKE 912

Query: 776 YM-KIKDE 782
           ++ K+K+E
Sbjct: 913 WIRKVKEE 920

Lambda     K      H
   0.321    0.137    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 1951
Number of extensions: 103
Number of successful extensions: 14
Number of sequences better than 10.0: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 811
Length of database: 964
Length adjustment: 43
Effective length of query: 768
Effective length of database: 921
Effective search space:   707328
Effective search space used:   707328
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 30 (16.8 bits)
S2: 30 (16.2 bits)