>YOR027W STI1 SGDID:S000005553, Chr XV from 381053-382822, Verified
           ORF, "Hsp90 cochaperone, interacts with the Ssa group of
           the cytosolic Hsp70 chaperones; activates the ATPase
           activity of Ssa1p; homolog of mammalian Hop protein"
          Length = 589

 Score =  275 bits (702), Expect = 5e-78
 Identities = 178/585 (30%), Positives = 285/585 (48%), Gaps = 32/585 (5%)

Query: 7   AQRLKELGNKCFQEGKYEEAVKYFSDAI-TNDPLDHVLYSNLSGAFASLGRFYEALESAN 65
           A   K+ GN  F    Y++A++ F+ AI  ++  +HVLYSN S  + SL +F +AL  AN
Sbjct: 5   ADEYKQQGNAAFTAKDYDKAIELFTKAIEVSETPNHVLYSNRSACYTSLKKFSDALNDAN 64

Query: 66  KCISIKKDWPKGYIRKGCAEHGLRQLSNAEKTYLEGLKIDPNNKSLQDALSKVRNENMLE 125
           +C+ I   W KGY R G A  GL  L  AE  Y + L++D +NK+ ++ L +V       
Sbjct: 65  ECVKINPSWSKGYNRLGAAHLGLGDLDEAESNYKKALELDASNKAAKEGLDQVHRTQQAR 124

Query: 126 NAQLIAHLNNIIENDPQL-----KSYKEENSNYPHELLNTIKSINSNPMNIRIILSTCHP 180
            AQ    L  +   DP L     K+ K        +L+  +     NP  I   L T  P
Sbjct: 125 QAQPDLGLTQLFA-DPNLIENLKKNPKTSEMMKDPQLVAKLIGYKQNPQAIGQDLFT-DP 182

Query: 181 KISXXXXXXXXXXXXXXXNDAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNRTPEQ 240
           ++                 +                                  ++ P++
Sbjct: 183 RLMTIMATLMGVDLNMDDINQSNSMPKEPETSKSTEQKKDAEPQSDSTTSKENSSKAPQK 242

Query: 241 ----------IQGDEHKLKGNE-------FYKQKKFDEALKEYEEAIQINPNDIMYHYNK 283
                     +  D+ K++ ++       FYK ++FDEA++ Y +A +++  DI Y  N+
Sbjct: 243 EESKESEPMEVDEDDSKIEADKEKAEGNKFYKARQFDEAIEHYNKAWELH-KDITYLNNR 301

Query: 284 AAVHIEMKNYDKAVETCLYAIENRYNFKAEFIQVAKLYNRLAISYINMKKYDLAIEAYRK 343
           AA   E   Y+ A+ T   A+E     +A++  ++K + R+  +Y  +      IE Y+K
Sbjct: 302 AAAEYEKGEYETAISTLNDAVEQGREMRADYKVISKSFARIGNAYHKLGDLKKTIEYYQK 361

Query: 344 SLVEDNNRATRNAXXXXXXXXXXXXXXAYIDPDKAEEHKNKGNEYFKNNDFPNAKKEYDE 403
           SL E                       AY++P+KAEE + +G EYF  +D+PNA K Y E
Sbjct: 362 SLTEHRTADILTKLRNAEKELKKAEAEAYVNPEKAEEARLEGKEYFTKSDWPNAVKAYTE 421

Query: 404 AIRRNPNDAKLYSNRAAALTKLIEYPSALEDVMKAIELDPTFVKAYSRKGNLHFFMKDYY 463
            I+R P DA+ YSNRAAAL KL+ +P A+ D  KAIE DP FV+AY RK      +K+Y 
Sbjct: 422 MIKRAPEDARGYSNRAAALAKLMSFPEAIADCNKAIEKDPNFVRAYIRKATAQIAVKEYA 481

Query: 464 KALQAYN--KGLELDPNN----KECLEGYQRCAFKIDEMSKSEKVDEEQFKKSMADPEIQ 517
            AL+  +  +  + + NN    +E  + Y + + +  +   S +  EE ++++M DPE+ 
Sbjct: 482 SALETLDAARTKDAEVNNGSSAREIDQLYYKASQQRFQPGTSNETPEETYQRAMKDPEVA 541

Query: 518 QIISDPQFQIILQKLNENPNSISEYIKDPKIFNGLQKLIAAGILK 562
            I+ DP  Q ILQ+  +NP ++ E++K+P++F  +Q LIAAGI++
Sbjct: 542 AIMQDPVMQSILQQAQQNPAALQEHMKNPEVFKKIQTLIAAGIIR 586

 Score = 54.7 bits (130), Expect = 1e-11
 Identities = 31/96 (32%), Positives = 52/96 (54%)

Query: 2   VNKEEAQRLKELGNKCFQEGKYEEAVKYFSDAITNDPLDHVLYSNLSGAFASLGRFYEAL 61
           VN E+A+  +  G + F +  +  AVK +++ I   P D   YSN + A A L  F EA+
Sbjct: 391 VNPEKAEEARLEGKEYFTKSDWPNAVKAYTEMIKRAPEDARGYSNRAAALAKLMSFPEAI 450

Query: 62  ESANKCISIKKDWPKGYIRKGCAEHGLRQLSNAEKT 97
              NK I    ++ + YIRK  A+  +++ ++A +T
Sbjct: 451 ADCNKAIEKDPNFVRAYIRKATAQIAVKEYASALET 486

 Score = 48.9 bits (115), Expect = 6e-10
 Identities = 29/117 (24%), Positives = 66/117 (56%), Gaps = 11/117 (9%)

Query: 241 IQGDEHKLKGNEFYKQKKFDEALKEYEEAIQIN--PNDIMYHYNKAAVHIEMKNYDKAVE 298
           +  DE+K +GN  +  K +D+A++ + +AI+++  PN ++Y  N++A +  +K +  A+ 
Sbjct: 3   LTADEYKQQGNAAFTAKDYDKAIELFTKAIEVSETPNHVLYS-NRSACYTSLKKFSDALN 61

Query: 299 TCLYAIENRYNFKAEFIQVAKLYNRLAISYINMKKYDLAIEAYRKSL-VEDNNRATR 354
                ++   ++       +K YNRL  +++ +   D A   Y+K+L ++ +N+A +
Sbjct: 62  DANECVKINPSW-------SKGYNRLGAAHLGLGDLDEAESNYKKALELDASNKAAK 111

 Score = 39.7 bits (91), Expect = 3e-07
 Identities = 44/180 (24%), Positives = 83/180 (46%), Gaps = 16/180 (8%)

Query: 3   NKEEAQRLKELGNKCFQEGKYEEAVKYFSDAITNDPLDHVLYSNLSGAFASLGRFYEALE 62
           +K EA + K  GNK ++  +++EA+++++ A      D    +N + A    G +  A+ 
Sbjct: 258 SKIEADKEKAEGNKFYKARQFDEAIEHYNKAWELHK-DITYLNNRAAAEYEKGEYETAIS 316

Query: 63  SANKCI----SIKKDW---PKGYIRKGCAEHGLRQLSNAEKTYLEGLKIDPNNKSLQDAL 115
           + N  +     ++ D+    K + R G A H L  L    + Y + L          D L
Sbjct: 317 TLNDAVEQGREMRADYKVISKSFARIGNAYHKLGDLKKTIEYYQKSL----TEHRTADIL 372

Query: 116 SKVRN-ENMLENAQLIAHLNNIIENDPQLKSYKE--ENSNYPHELLNTIKSINSNPMNIR 172
           +K+RN E  L+ A+  A++N     + +L+  KE    S++P+ +    + I   P + R
Sbjct: 373 TKLRNAEKELKKAEAEAYVNPEKAEEARLEG-KEYFTKSDWPNAVKAYTEMIKRAPEDAR 431

Lambda     K      H
   0.313    0.132    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 1081
Number of extensions: 98
Number of successful extensions: 45
Number of sequences better than 10.0: 1
Number of HSP's gapped: 11
Number of HSP's successfully gapped: 10
Length of query: 564
Length of database: 589
Length adjustment: 36
Effective length of query: 528
Effective length of database: 553
Effective search space:   291984
Effective search space used:   291984
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 27 (15.1 bits)
S2: 27 (15.0 bits)