>YNR065C YNR065C SGDID:S000005348, Chr XIV from 753700-750350,
           reverse complement, Uncharacterized ORF, "Sortilin
           homolog, interacts with proteins of the endocytic
           machinery"
          Length = 1116

 Score =  198 bits (504), Expect = 1e-54
 Identities = 170/655 (25%), Positives = 299/655 (45%), Gaps = 95/655 (14%)

Query: 141 IMVNSVNKNIVLIIGNQKNHYISEDSGETFRL--LNYQNKINFWQFHSTKTHWALVSSWT 198
           ++ N    +   + G++ N + + D G +F +  L    ++      S K     +    
Sbjct: 329 VVFNPYFNSSAYLFGSKGNIFSTHDRGHSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGG 388

Query: 199 EACYSNDDNSGECMQTLSLTKDLGRTF-QLIDIYV-VQFNWGDKESHLEDTIYYTRHKNR 256
           + C S    S EC     LTKD G TF +++D  +  +F     E    + +   + K +
Sbjct: 389 KNCESI--LSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFEYPSNEEMVMCQVKKK 446

Query: 257 NGHQQRFSGWSKDVDFVATHNFGKSVDVLVKQGNKFLISNGYIFVAKLNDVIKQTVNMMV 316
           +   +        +DF    N      ++ +    +L + GYI VA  ++     +   V
Sbjct: 447 SSETRSLVS---SIDFFQGDN-----KIIFENIIGYLSTGGYIIVAVPHE--DNELRAYV 496

Query: 317 STDGGKTFNKANLP---ENIHEKSYTVLDTSEGSIMLHVNHGTSSEKINTGNVYISDASG 373
           + DG + F +A  P   +   ++++T+L + +GSI LH+     S   + GN+  S+++G
Sbjct: 497 TIDGTE-FAEAKFPYGQDVSKQEAFTILGSEKGSIFLHLATNLESGH-DFGNLLKSNSNG 554

Query: 374 LNYTLSLPNNIRTSSGECEFDRVLSLDGVYIANFLDVNNEIKDEDLRFQNFKSAIEEDIA 433
            ++        R + G  +F++V  L+G+ I N +                         
Sbjct: 555 TSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIV------------------------- 589

Query: 434 PFETNTEKRKKQYNKGKNEDAVRTVISFNKGGEWSYLKAPKVDSRGNKYECG----DNCY 489
              +N EK      + K ++ ++T I+FN G +W++LK PK DS G K+ C     D C 
Sbjct: 590 ---SNREK----VGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCS 642

Query: 490 LHLHGITNYHQYAPFYSIENAVGIIMGTGNVGSHLRYESDEVNTFLSRDGGVTWIEAHKG 549
           LHLHG T        YS  +A+G++ G GNVG  L    +E +TFL+ DGG TW E  KG
Sbjct: 643 LHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDKL-LPYEECSTFLTTDGGETWTEVKKG 701

Query: 550 PYIYEYGDYGGLIVMADDLRKTNQIVFSWNEGQSWFDFELGQFSIDVDNIVAEPNSASVE 609
           P+ +EYGD+GG++V+  +  +T+ I +S + G++W D++     + V +I+  P  +++ 
Sbjct: 702 PHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALR 761

Query: 610 FLVYGTRNDVGV----LYHLDFNALGQPLCKGLWAADSVSSDYETWSPTSGNFNDKCILG 665
           FL++G   ++G      Y +DF  + +  C+         +D++ +SP        C+ G
Sbjct: 762 FLLFGEAKNMGSGSFRTYTIDFRNIFERQCE-FDITGKKRADFK-YSPLGSRTG--CLFG 817

Query: 666 RKITYTRRKQTSECFNG----KDLKRTVDKKPCECTPEDYECETGFTRKIGSYECKPNDP 721
            +  +  RK   +CF G     +  R V  K C CT +D+EC+  F  K     CK    
Sbjct: 818 HQTEFL-RKTDEKCFIGNIPLSEFSRNV--KNCSCTRQDFECDYNF-YKASDGTCK---- 869

Query: 722 TLTIEGCTSSS-------------YFYANAYRKVPGDICVNGWVPEK--VPVPCP 761
              ++G +S++             Y+ ++ YRK+P   C  G   +    P PCP
Sbjct: 870 --LVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHPCP 922

 Score = 95.5 bits (236), Expect = 2e-23
 Identities = 78/271 (28%), Positives = 116/271 (42%), Gaps = 42/271 (15%)

Query: 517 TGNVGSHLRYESDEVNTFLSRDGGVTWIEAHKGPYIYEYGDYGGLIVM-----ADDLRKT 571
           TG+VG    ++ ++  TF+SRDGG+TW   H    +Y  GD G +IV       +D    
Sbjct: 4   TGSVGDGSEFDWEDQKTFISRDGGLTWRFVHNSSGLYATGDLGNIIVYIPYDPEEDGDFQ 63

Query: 572 NQIVFSWNEGQSWFDFELGQFSIDVDN---IVAEPNSASVEFLVYGT-------RNDV-- 619
           ++  +S ++G++W ++EL      V     I   P+ +  +F+  GT        N +  
Sbjct: 64  SEFYYSLDQGRTWNEYELTNAISSVHPYKLINPTPDGSGSKFIFKGTFATTDSETNSITS 123

Query: 620 --GVLYHLDFNALGQPLCKGLWAADS---VSSDYETWSPTSGNFNDKCILGRKITYTRRK 674
             GV Y +DF+A          A DS      D+E W    G    KC+ G K  Y RRK
Sbjct: 124 LKGVEYIIDFSA----------AFDSRTCEEEDFEDWDLADG----KCVNGAKYKYRRRK 169

Query: 675 QTSECFNGKDLK-RTVDKKPC-ECTPEDYECETGFTRKIGSYECKPNDPTLTIEGCTSSS 732
           Q ++C   K  K  ++D+ PC  C   DYEC   F R      C P+   +        S
Sbjct: 170 QDAQCLVKKAFKDLSLDETPCNSCGESDYECSFEFVRDANGL-CIPDYNLIAFSNICDKS 228

Query: 733 ---YFYANAYRKVPGDICVNGWVPEKVPVPC 760
                     + + GD C      E V +PC
Sbjct: 229 KDKSVLVEPLQLIKGDECKTPMKIEPVDIPC 259

 Score = 21.2 bits (43), Expect = 0.39
 Identities = 11/47 (23%), Positives = 22/47 (46%), Gaps = 2/47 (4%)

Query: 72  INFDSAVDD--VQWCGNNHMTVLVKTVKGRLYRSSDGGKIWTNITGN 116
           ++F +   D  + + G N  ++L        Y + DGG+ +T +  N
Sbjct: 373 LDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDN 419

 Score = 20.0 bits (40), Expect = 0.86
 Identities = 5/13 (38%), Positives = 10/13 (76%)

Query: 101 YRSSDGGKIWTNI 113
           + ++DGG+ WT +
Sbjct: 686 FLTTDGGETWTEV 698

 Score = 18.5 bits (36), Expect = 2.5
 Identities = 11/35 (31%), Positives = 18/35 (51%), Gaps = 1/35 (2%)

Query: 140 LIMVNSVNKNIVLIIGNQKNHYISEDSGETFRLLN 174
           ++M  SV         +QK  +IS D G T+R ++
Sbjct: 1   MLMTGSVGDGSEFDWEDQKT-FISRDGGLTWRFVH 34

 Score = 18.1 bits (35), Expect = 3.3
 Identities = 9/20 (45%), Positives = 9/20 (45%)

Query: 107 GKIWTNITGNLSDKENNKSD 126
           G I TNI  N      NK D
Sbjct: 582 GIIITNIVSNREKVGENKED 601

 Score = 17.7 bits (34), Expect = 4.3
 Identities = 11/44 (25%), Positives = 16/44 (36%), Gaps = 3/44 (6%)

Query: 826  NVFEPEMEFIDAEQDDNEEDVPTLLPYSSDRNRSTNKDFTLARN 869
            + + PE E           ++P  LP    R+     D T  RN
Sbjct: 1073 DAYRPEQEHTSQIDQPATSNIPDALP---ARSAIHKPDSTAVRN 1113

Lambda     K      H
   0.315    0.133    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 2614
Number of extensions: 168
Number of successful extensions: 25
Number of sequences better than 10.0: 1
Number of HSP's gapped: 12
Number of HSP's successfully gapped: 12
Length of query: 895
Length of database: 1116
Length adjustment: 44
Effective length of query: 851
Effective length of database: 1072
Effective search space:   912272
Effective search space used:   912272
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 31 (17.0 bits)
S2: 31 (16.5 bits)