Query= PF14_0602 Pf
Annotation|Plasmodium_falciparum_TIGR|(protein coding) DNA polymerase
alpha subunit, putative
(539 letters)
>YBL035C POL12 SGDID:S000000131, Chr II from 153613-151496, reverse
complement, Verified ORF, "B subunit of DNA polymerase
alpha-primase complex, required for initiation of DNA
replication during mitotic and premeiotic DNA synthesis;
also functions in telomere capping and length
regulation"
Length = 705
Score = 82.0 bits (201), Expect = 7e-20
Identities = 89/366 (24%), Positives = 154/366 (42%), Gaps = 45/366 (12%)
Query: 106 ENYKFLGLDTNV--ICDCINKKISLFLELFLKYSKKLNLNIEIEPILNMSDDESYIFGRI 163
+ YKF + N+ D ++ +I F ++ + K L+ N +P + S E Y GRI
Sbjct: 243 KKYKFRTMRQNLQEASDVLDDQIESFTKIIQNHYK-LSPNDFADPTIQ-SQSEIYAVGRI 300
Query: 164 YTEN---EMNISESNIILEGNMKWNNGDKAQLLNLTDMRNICFFLGQILAIKGKKEINQF 220
++ + ++ ++ LE + G + +L +L+ + + FFLGQI+A KGK
Sbjct: 301 VPDSPTYDKFLNPESLSLETSRMGGVGRRVRL-DLSQVNELSFFLGQIVAFKGKNANGD- 358
Query: 221 SIKYYVSNVYAGLPSHLKVQIDKEFVLKHFNTKEIEEDSKIHENILHLYNNENIHIMICN 280
Y+ N LP + + ++ E +L + I+ C
Sbjct: 359 ---YFTVNSILPLP---------------YPNSPVSTSQELQEFQANLEGSSLKVIVTCG 400
Query: 281 GYIYNDNNYSENLDNFLKVVNEKL-PHVVLIFGPFLYIR----------NFSETIQKIGD 329
Y NDN E L F+ +N ++ PHV+++FGPF+ I NF + +
Sbjct: 401 PYFANDNFSLELLQEFIDSINNEVKPHVLIMFGPFIDITHPLIASGKLPNFPQFKTQPKT 460
Query: 330 INIIYENLFKKITKFAKNEILEKTHFFIIPSIYDSI-NIYPLPQPPFYYENSNINSPNVH 388
++ ++ LF I K I +IPS D+I N PQ + + N
Sbjct: 461 LDELFLKLFTPILKTISPHI----QTVLIPSTKDAISNHAAYPQASLIRKALQLPKRNFK 516
Query: 389 FLSNPSYIYINELKIALTSCDIVYNLTRNLL--CRPSELKLFYLFEQILRQLSLFPSYPS 446
++NPS INE+ ++ D +L + S +L + E IL+Q +P +P
Sbjct: 517 CMANPSSFQINEIYFGCSNVDTFKDLKEVIKGGTTSSRYRLDRVSEHILQQRRYYPIFPG 576
Query: 447 EYNIEI 452
I
Sbjct: 577 SIRTRI 582
Score = 18.1 bits (35), Expect = 1.2
Identities = 9/31 (29%), Positives = 15/31 (48%), Gaps = 3/31 (9%)
Query: 459 LFQPNRLPDIFIYPSFTNEKSYIKEVHKKLF 489
L +LP+ +P F + + E+ KLF
Sbjct: 442 LIASGKLPN---FPQFKTQPKTLDELFLKLF 469
Score = 16.9 bits (32), Expect = 2.7
Identities = 8/25 (32%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Query: 137 SKKLNLNIEIEPILNMSDDESYIFG 161
S K+N + + +P++ S + S +FG
Sbjct: 82 SSKVNTSTK-KPVIKKSLNSSPLFG 105
Score = 16.2 bits (30), Expect = 4.6
Identities = 29/120 (24%), Positives = 52/120 (43%), Gaps = 18/120 (15%)
Query: 378 ENSNINS--PNVHFLSN--PSYIYINELKIA--LTSCDIVYNLTRNLLCRPSELKLFYLF 431
EN I+S PNV LS PSY N++K+ + + R L S++ L
Sbjct: 210 ENIEISSGNPNVGLLSTEEPSY---NQVKVEPFYDAKKYKFRTMRQNLQEASDV----LD 262
Query: 432 EQILRQLSLFPSY----PSEYNIEITKFKNLLFQPNRL-PDIFIYPSFTNEKSYIKEVHK 486
+QI + ++ P+++ + ++ ++ R+ PD Y F N +S E +
Sbjct: 263 DQIESFTKIIQNHYKLSPNDFADPTIQSQSEIYAVGRIVPDSPTYDKFLNPESLSLETSR 322
Lambda K H
0.320 0.140 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 897
Number of extensions: 56
Number of successful extensions: 11
Number of sequences better than 10.0: 1
Number of HSP's gapped: 4
Number of HSP's successfully gapped: 4
Length of query: 539
Length of database: 705
Length adjustment: 37
Effective length of query: 502
Effective length of database: 668
Effective search space: 335336
Effective search space used: 335336
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)