Query= PF14_0602 Pf Annotation|Plasmodium_falciparum_TIGR|(protein coding) DNA polymerase alpha subunit, putative (539 letters)
>YBL035C POL12 SGDID:S000000131, Chr II from 153613-151496, reverse
           complement, Verified ORF, "B subunit of DNA polymerase
           alpha-primase complex, required for initiation of DNA
           replication during mitotic and premeiotic DNA synthesis;
           also functions in telomere capping and length
           regulation"
          Length = 705

 Score = 82.0 bits (201), Expect = 7e-20
 Identities = 89/366 (24%), Positives = 154/366 (42%), Gaps = 45/366 (12%)

Query: 106 ENYKFLGLDTNV--ICDCINKKISLFLELFLKYSKKLNLNIEIEPILNMSDDESYIFGRI 163
           + YKF  +  N+    D ++ +I  F ++   + K L+ N   +P +  S  E Y  GRI
Sbjct: 243 KKYKFRTMRQNLQEASDVLDDQIESFTKIIQNHYK-LSPNDFADPTIQ-SQSEIYAVGRI 300

Query: 164 YTEN---EMNISESNIILEGNMKWNNGDKAQLLNLTDMRNICFFLGQILAIKGKKEINQF 220
             ++   +  ++  ++ LE +     G + +L +L+ +  + FFLGQI+A KGK      
Sbjct: 301 VPDSPTYDKFLNPESLSLETSRMGGVGRRVRL-DLSQVNELSFFLGQIVAFKGKNANGD- 358

Query: 221 SIKYYVSNVYAGLPSHLKVQIDKEFVLKHFNTKEIEEDSKIHENILHLYNNENIHIMICN 280
              Y+  N    LP               +    +    ++ E   +L  +    I+ C 
Sbjct: 359 ---YFTVNSILPLP---------------YPNSPVSTSQELQEFQANLEGSSLKVIVTCG 400

Query: 281 GYIYNDNNYSENLDNFLKVVNEKL-PHVVLIFGPFLYIR----------NFSETIQKIGD 329
            Y  NDN   E L  F+  +N ++ PHV+++FGPF+ I           NF +   +   
Sbjct: 401 PYFANDNFSLELLQEFIDSINNEVKPHVLIMFGPFIDITHPLIASGKLPNFPQFKTQPKT 460

Query: 330 INIIYENLFKKITKFAKNEILEKTHFFIIPSIYDSI-NIYPLPQPPFYYENSNINSPNVH 388
           ++ ++  LF  I K     I       +IPS  D+I N    PQ     +   +   N  
Sbjct: 461 LDELFLKLFTPILKTISPHI----QTVLIPSTKDAISNHAAYPQASLIRKALQLPKRNFK 516

Query: 389 FLSNPSYIYINELKIALTSCDIVYNLTRNLL--CRPSELKLFYLFEQILRQLSLFPSYPS 446
            ++NPS   INE+    ++ D   +L   +      S  +L  + E IL+Q   +P +P 
Sbjct: 517 CMANPSSFQINEIYFGCSNVDTFKDLKEVIKGGTTSSRYRLDRVSEHILQQRRYYPIFPG 576

Query: 447 EYNIEI 452
                I
Sbjct: 577 SIRTRI 582

 Score = 18.1 bits (35), Expect = 1.2
 Identities = 9/31 (29%), Positives = 15/31 (48%), Gaps = 3/31 (9%)

Query: 459 LFQPNRLPDIFIYPSFTNEKSYIKEVHKKLF 489
           L    +LP+   +P F  +   + E+  KLF
Sbjct: 442 LIASGKLPN---FPQFKTQPKTLDELFLKLF 469

 Score = 16.9 bits (32), Expect = 2.7
 Identities = 8/25 (32%), Positives = 16/25 (64%), Gaps = 1/25 (4%)

Query: 137 SKKLNLNIEIEPILNMSDDESYIFG 161
           S K+N + + +P++  S + S +FG
Sbjct: 82  SSKVNTSTK-KPVIKKSLNSSPLFG 105

 Score = 16.2 bits (30), Expect = 4.6
 Identities = 29/120 (24%), Positives = 52/120 (43%), Gaps = 18/120 (15%)

Query: 378 ENSNINS--PNVHFLSN--PSYIYINELKIA--LTSCDIVYNLTRNLLCRPSELKLFYLF 431
           EN  I+S  PNV  LS   PSY   N++K+     +    +   R  L   S++    L 
Sbjct: 210 ENIEISSGNPNVGLLSTEEPSY---NQVKVEPFYDAKKYKFRTMRQNLQEASDV----LD 262

Query: 432 EQILRQLSLFPSY----PSEYNIEITKFKNLLFQPNRL-PDIFIYPSFTNEKSYIKEVHK 486
           +QI     +  ++    P+++     + ++ ++   R+ PD   Y  F N +S   E  +
Sbjct: 263 DQIESFTKIIQNHYKLSPNDFADPTIQSQSEIYAVGRIVPDSPTYDKFLNPESLSLETSR 322
Lambda     K      H
   0.320    0.140    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 897
Number of extensions: 56
Number of successful extensions: 11
Number of sequences better than 10.0: 1
Number of HSP's gapped: 4
Number of HSP's successfully gapped: 4
Length of query: 539
Length of database: 705
Length adjustment: 37
Effective length of query: 502
Effective length of database: 668
Effective search space:   335336
Effective search space used:   335336
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)