>YLR420W URA4 SGDID:S000004412, Chr XII from 963782-964876, Verified
           ORF, "Dihydroorotase, catalyzes the third enzymatic step
           in the de novo biosynthesis of pyrimidines, converting
           carbamoyl-L-aspartate into dihydroorotate"
          Length = 364

 Score =  171 bits (434), Expect = 2e-47
 Identities = 112/370 (30%), Positives = 181/370 (48%), Gaps = 47/370 (12%)

Query: 12  DMHCHLRQGDMLDFTVNSIRRGGCNRVLVMPNTHPIISTCSDAQKYLYQLKSRDDDIEYL 71
           DMH H+R+G M +     IR GG +   +MPN  P I+T     +Y   L+       +L
Sbjct: 12  DMHVHVREGAMCELVTPKIRDGGVSIAYIMPNLQPPITTLDRVIEYKKTLQKLAPKTTFL 71

Query: 72  MTLYLNKNTDENDILSNYYKCNLQGVKIYPSNVTTNSSDGI--TSLEPYYKVFHALEKLN 129
           M+ YL+K+   + I     +  ++GVK YP+ VTTNS+ G+       +Y +F A+++ N
Sbjct: 72  MSFYLSKDLTPDLIHEAAQQHAIRGVKCYPAGVTTNSAAGVDPNDFSAFYPIFKAMQEEN 131

Query: 130 KSIHIHCEEPN--------INPLYAEEKYLPHIHDLAIKFPGLNIVLEHISSSESINVIK 181
             +++H E+P+        I+ L AEE +LP +  L   FP L I+LEH +S  +I  I+
Sbjct: 132 LVLNLHGEKPSVHDGDKEPIHVLNAEEAFLPALKKLHNDFPNLKIILEHCTSESAIKTIE 191

Query: 182 EFR---------NVAGSITPHHLYLTIDDVVNMDIYDHAIDNTYIEKYIKNTYHYCKPLP 232
           +            VA ++T HHL+LTIDD                  +  N  ++CKP+ 
Sbjct: 192 DINKNVKKATDVKVAATLTAHHLFLTIDD------------------WAGNPVNFCKPVA 233

Query: 233 KLLEDKIALQDVIKDDFPRVFLGSDSAPHYKVMKRKPYYK---PGIYTQPFLINYVAHIL 289
           KL  DK AL        P  F GSDSAPH   ++ K  Y+    G+Y+Q F I Y+A + 
Sbjct: 234 KLPNDKKALVKAAVSGKPYFFFGSDSAPH--PVQNKANYEGVCAGVYSQSFAIPYIAQVF 291

Query: 290 NKFDALDKMENFTSKNASLFLNLAEKKKLAKYYICVEKHPFKLPREYN-----GVVPFLA 344
            + +AL+ ++ F S     F  + + +  +     + K    +P+  +      ++PF A
Sbjct: 292 EEQNALENLKGFVSDFGISFYEVKDSEVASSDKAILFKKEQVIPQVISDGKDISIIPFKA 351

Query: 345 GKTLDYDIHY 354
           G  L + + +
Sbjct: 352 GDKLSWSVRW 361

 Score = 15.8 bits (29), Expect = 2.0
 Identities = 9/23 (39%), Positives = 11/23 (47%)

Query: 335 EYNGVVPFLAGKTLDYDIHYVSK 357
           EY   +  LA KT      Y+SK
Sbjct: 56  EYKKTLQKLAPKTTFLMSFYLSK 78

Lambda     K      H
   0.321    0.139    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 369
Number of extensions: 24
Number of successful extensions: 8
Number of sequences better than 10.0: 1
Number of HSP's gapped: 2
Number of HSP's successfully gapped: 2
Length of query: 358
Length of database: 364
Length adjustment: 29
Effective length of query: 329
Effective length of database: 335
Effective search space:   110215
Effective search space used:   110215
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 23 (13.5 bits)
S2: 23 (13.5 bits)