>YJL074C SMC3 SGDID:S000003610, Chr X from 302766-299074, reverse
            complement, Verified ORF, "Subunit of the multiprotein
            cohesin complex required for sister chromatid cohesion in
            mitotic cells; also required, with Rec8p, for cohesion
            and recombination during meiosis; phylogenetically
            conserved SMC chromosomal ATPase family member"
          Length = 1230

 Score =  332 bits (852), Expect = 9e-95
 Identities = 299/1280 (23%), Positives = 570/1280 (44%), Gaps = 142/1280 (11%)

Query: 1    MYIKQIRLKGFRTYKNETTID-FTRGINCIVGFNGSGKSNILLAIEFILSDVC-----EY 54
            MYIK++ +KGF+TY+NET ID F+   N I+G NGSGKSN   AI F+LSD       E 
Sbjct: 1    MYIKRVIIKGFKTYRNETIIDNFSPHQNVIIGSNGSGKSNFFAAIRFVLSDDYSNLKREE 60

Query: 55   KQIYLHEGIGNAVRNCYVEIIFDNSEKYFSMFK------ESEIKIKKVLENMKCEIFVND 108
            +Q  +H+G G +V +  VEI+F + +    +        + E+ I++ +   K +  +ND
Sbjct: 61   RQGLIHQGSGGSVMSASVEIVFHDPDHSMILPSGVLSRGDDEVTIRRTVGLKKDDYQLND 120

Query: 109  KNISKNQYVELLESCGLCINNLYNIIKQGQIIKLSNMKDEEILNYLKSILGAKIFEEKKK 168
            +N++K   V +LE+ G  +NN YNI+ QG+I+ L+N KD+E L  L+ ++GAK FE K K
Sbjct: 121  RNVTKGDIVRMLETAGFSMNNPYNIVPQGKIVALTNAKDKERLQLLEDVVGAKSFEVKLK 180

Query: 169  DALSMLKECDSKKVTIEKEFNDMNSKLESLQEEFENFLEYKKLEKEK-----VHLDYFLN 223
             +L  ++E + KK+ I KE  ++NSKL  +++E +   +Y +LE+ +        D  LN
Sbjct: 181  ASLKKMEETEQKKIQINKEMGELNSKLSEMEQERKELEKYNELERNRKIYQFTLYDRELN 240

Query: 224  EI---------NYKN-IYEETQML------KSKLQELKNKTQDEDNHLNLSNN------- 260
            E+         +Y N +Y   Q +      +  + ++  K    +  L + N        
Sbjct: 241  EVINQMERLDGDYNNTVYSSEQYIQELDKREDMIDQVSKKLSSIEASLKIKNATDLQQAK 300

Query: 261  -NKSEYNEKLNKMKLEIASCQNHLNKTISEDIQNKRNIVHLQMLXXXXXXXXXXXXXXXX 319
              +SE ++KL  + ++I   Q  +     E  + +RN+    +                 
Sbjct: 301  LRESEISQKLTNVNVKIKDVQQQI-----ESNEEQRNLDSATLKEIKSIIEQRKQKLSKI 355

Query: 320  XXXXXXXXXXEFILRVN-EKLQSLKSDIVSXXXXXXXXXXXXXMLLSKNKNKNTDANYSH 378
                      E + ++    LQ  + D++                 ++ K+K+    + H
Sbjct: 356  LPRYQELTKEEAMYKLQLASLQQKQRDLILKKGE-----------YARFKSKDERDTWIH 404

Query: 379  N-VKKIEKMINDINIELSFLEKETIXXXXXXXXXXXXXXXXXXXIKENETLSQ--KYGSE 435
            + +++++  I ++N   S L+ +                     I   +T  Q   + SE
Sbjct: 405  SEIEELKSSIQNLNELESQLQMDRTSLRKQYSAIDEEIEELIDSINGPDTKGQLEDFDSE 464

Query: 436  INELNNKSEKCVEQKRQCQQKISEGTTNLNEIKCQIIEVNDKYDEIIKSSNKEILKIVDL 495
            +  L  K  + ++ +++  +K  +  T L  +   + +     +E +  S    +  V  
Sbjct: 465  LIHLKQKLSESLDTRKELWRKEQKLQTVLETLLSDVNQNQRNVNETMSRSLANGIINVKE 524

Query: 496  IMAEKSIKRENILGFLIDNINVDKTYVKAVDTILENHYFTLIVEDMQTAKKIVEFIEKKR 555
            I  +  I  E++ G L + I V+  Y    + I  N  F ++V+  +TA  I+  + + +
Sbjct: 525  ITEKLKISPESVFGTLGELIKVNDKYKTCAEVIGGNSLFHIVVDTEETATLIMNELYRMK 584

Query: 556  EERTSKEFNFKEFYFGKLTIVPLLNIKKFNEFNYPNDK----NIVPLIKCVNYNSKIYEF 611
                           G++T +PL  +   ++  +P++        PLIK + Y  +  + 
Sbjct: 585  G--------------GRVTFIPLNRLSLDSDVKFPSNTTTQIQFTPLIKKIKYEPRFEKA 630

Query: 612  LKNILFKTIIVKSL-ESCENYLEDNYNCVNIDGDYLSKHGFMXXXXXXXXXXI------- 663
            +K++  KTI+VK L +  +   +   N + +DGD   K G +                  
Sbjct: 631  VKHVFGKTIVVKDLGQGLKLAKKHKLNAITLDGDRADKRGVLTGGYLDQHKRTRLESLKN 690

Query: 664  --------YTVYNXXXXXXXXXXXXXSHIEELNNNIEKIDDE----LRNIYDTKSSTVAK 711
                      +               + I+++N NI K+ ++    L NI   ++S   K
Sbjct: 691  LNESRSQHKKILEELDFVRNELNDIDTKIDQVNGNIRKVSNDRESVLTNIEVYRTSLNTK 750

Query: 712  KNGCASTXXXXXXXXXXXXXXXRLTSEKIN----YIQEKKQNLEQHKDQLKMQILQLRNN 767
            KN                     L  EK+N    + QEK    E         +LQ  ++
Sbjct: 751  KN--------EKLILEESLNAIILKLEKLNTNRTFAQEKLNTFEN-------DLLQEFDS 795

Query: 768  NVNPDESEKVGS--TDINSLNDEVKKLKEELNKIRNEYDDFKNKLE--LLYQKRNENDSS 823
             ++ +E E++ S   +I++ ++++    + L  I    D    +LE  L+ Q   END  
Sbjct: 796  ELSKEEKERLESLTKEISAAHNKLNITSDALEGITTTIDSLNAELESKLIPQ---ENDLE 852

Query: 824  IYMEEYEDVDIDEYNNDLADKKDHSDKIEKEKIHYEQKIREINKEMENVKSSIDXXXXXX 883
              M E  D  I    ++L + +   + +EK+  +   ++  + +E+E++ +         
Sbjct: 853  SKMSEVGDAFIFGLQDELKELQLEKESVEKQHENAVLELGTVQREIESLIAEETNNKKLL 912

Query: 884  XXXXXXXXXXCHQMNQINEELRILEGKEENIRKKKVLLPQGIQEL---------EEYRTY 934
                        +++   + +     K+  +  ++  L Q I+E+          ++   
Sbjct: 913  EKANNQQRLLLKKLDNFQKSVEKTMIKKTTLVTRREELQQRIREIGLLPEDALVNDFSDI 972

Query: 935  DKQQLSAKLKSVTMELKKYSNVNEKAGDRLNILMNDFNELKKRHEEINSSHKNIKDMIQH 994
               QL  +L  +  E+    NVN++A +          +L +R  E++ S  +I+D+I  
Sbjct: 973  TSDQLLQRLNDMNTEISGLKNVNKRAFENFKKFNERRKDLAERASELDESKDSIQDLIVK 1032

Query: 995  IGKKKDEALEATYVKINKYFSEYFSLLFKNRKASLVLKKMNE--KEYKEKLQ-EM-SEKR 1050
            + ++K  A+++T+ K+++ F   F  L     A L++ + N+   ++ E +  +M +E  
Sbjct: 1033 LKQQKVNAVDSTFQKVSENFEAVFERLVPRGTAKLIIHRKNDNANDHDESIDVDMDAESN 1092

Query: 1051 IKRRIIDEEVYIDKITGISINITSNDDEKMTYTIQELSGGERSIVAICLFLCLNKIDNFS 1110
              +   D E+     TG+SI+++ N  +     +++LSGG++++ AI L L +  +D  S
Sbjct: 1093 ESQNGKDSEI---MYTGVSISVSFNSKQNEQLHVEQLSGGQKTVCAIALILAIQMVDPAS 1149

Query: 1111 FFFFDEIDAALDTIHRDNLSLLLKELAHRGTQFIITTFRKELLEYSDNMYIVKIVDRESY 1170
            F+ FDEIDAALD  +R  ++ LLKEL+ +  QFI TTFR ++L+ +D  + VK  ++ S 
Sbjct: 1150 FYLFDEIDAALDKQYRTAVATLLKELS-KNAQFICTTFRTDMLQVADKFFRVKYENKIST 1208

Query: 1171 ISKGTKNEAYEIISIEEKHA 1190
            + +  + EA   I    K A
Sbjct: 1209 VIEVNREEAIGFIRGSNKFA 1228

 Score = 20.0 bits (40), Expect = 1.3
 Identities = 11/38 (28%), Positives = 20/38 (52%)

Query: 1155 YSDNMYIVKIVDRESYISKGTKNEAYEIISIEEKHALE 1192
            YS   YI ++  RE  I + +K  +    S++ K+A +
Sbjct: 258  YSSEQYIQELDKREDMIDQVSKKLSSIEASLKIKNATD 295

Lambda     K      H
   0.314    0.133    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 3945
Number of extensions: 267
Number of successful extensions: 49
Number of sequences better than 10.0: 1
Number of HSP's gapped: 25
Number of HSP's successfully gapped: 25
Length of query: 1193
Length of database: 1230
Length adjustment: 47
Effective length of query: 1146
Effective length of database: 1183
Effective search space:  1355718
Effective search space used:  1355718
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 33 (17.8 bits)
S2: 33 (17.3 bits)