>YKR059W TIF1 SGDID:S000001767, Chr XI from 554629-555816, Verified
           ORF, "Translation initiation factor eIF4A, identical to
           Tif2p; DEA(D/H)-box RNA helicase that couples ATPase
           activity to RNA binding and unwinding; forms a dumbbell
           structure of two compact domains connected by a linker;
           interacts with eIF4G"
          Length = 395

 Score =  430 bits (1106), Expect = e-125
 Identities = 201/377 (53%), Positives = 286/377 (75%), Gaps = 1/377 (0%)

Query: 14  EICTSFENIGIDEGLLRGIYAYGFEKPSAIQQRGIKPILNGRDVILQSQSGTGKTCVFAV 73
           ++   F+++ +DE LLRG++ YGFE+PSAIQQR I PI+ G DV+ Q+QSGTGKT  F++
Sbjct: 19  KVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSI 78

Query: 74  GALNCVNRNLNETQVIILSPTRELAEQTQKVCLALADYIHVTIYCCIGGKKMSDDIKALN 133
            AL  ++ ++   Q ++L+PTRELA Q QKV +ALA ++ + ++ CIGG    +D + L 
Sbjct: 79  AALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGLR 138

Query: 134 NGVHVISGTPGRIYHMLNLRHLKCKYIKQLVIDEADEMLNKGFKEQVYDIYRFLSPNTQI 193
           +   ++ GTPGR++  +  R  +   IK  ++DEADEML+ GFKEQ+Y I+  L P TQ+
Sbjct: 139 DA-QIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQV 197

Query: 194 ILSSATLPQEVLEITNKFMHKPVKILVKRDELTLEGIKQFFVSIEKEQWKYETLADLYES 253
           +L SAT+P +VLE+T KFM  PV+ILVK+DELTLEGIKQF+V++E+E++KYE L DLY+S
Sbjct: 198 VLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDS 257

Query: 254 LTITQAVVFCNTQMKVDWLTKKMLESNFTVCKMHAGMSQSERDDIMLKFRQCKFRVLIST 313
           +++TQAV+FCNT+ KV+ LT K+    FTV  +++ + Q ERD IM +FR    R+LIST
Sbjct: 258 ISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILIST 317

Query: 314 DIWGRGLDVQEVSLVVNYDLPNSRESYIHRIGRSGRFGRKGVAINFVKNDDIKILRDIEQ 373
           D+  RG+DVQ+VSLV+NYDLP ++E+YIHRIGR GRFGRKGVAINFV N+D+  +R++E+
Sbjct: 318 DLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVAINFVTNEDVGAMRELEK 377

Query: 374 YYSTQIDEMPMNITELL 390
           +YSTQI+E+P +I  LL
Sbjct: 378 FYSTQIEELPSDIATLL 394

 Score = 17.3 bits (33), Expect = 0.80
 Identities = 5/12 (41%), Positives = 8/12 (66%)

Query: 321 DVQEVSLVVNYD 332
           D++E  +  NYD
Sbjct: 7   DIEESQIQTNYD 18

Lambda     K      H
   0.321    0.138    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 459
Number of extensions: 18
Number of successful extensions: 7
Number of sequences better than 10.0: 1
Number of HSP's gapped: 2
Number of HSP's successfully gapped: 2
Length of query: 390
Length of database: 395
Length adjustment: 31
Effective length of query: 359
Effective length of database: 364
Effective search space:   130676
Effective search space used:   130676
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 24 (14.0 bits)
S2: 24 (13.9 bits)