>YDR097C MSH6 SGDID:S000002504, Chr IV from 643833-640105, reverse
            complement, Verified ORF, "Protein required for mismatch
            repair in mitosis and meiosis, forms a complex with Msh2p
            to repair both single-base & insertion-deletion mispairs;
            potentially phosphorylated by Cdc28p"
          Length = 1242

 Score =  367 bits (941), Expect = e-105
 Identities = 288/995 (28%), Positives = 453/995 (45%), Gaps = 123/995 (12%)

Query: 370  RDINLRTPDHADYDSSTIWTPPPDHKWAIEYKQAHYTPGMQQFWKIKSRNFDKIIFFKMG 429
            RD   R     +YD  T++ P     W        +TP  +Q+W+IKS+ +D I+FFK G
Sbjct: 284  RDAQRRPKSDPEYDPRTLYIP--SSAWN------KFTPFEKQYWEIKSKMWDCIVFFKKG 335

Query: 430  RFYEIFYIDACLMHTICSLNWMSG--EHKPHLGFPEQSLHFYAKKVINSGHKVVVIEQME 487
            +F+E++  DA L + +  L    G   +    G PE S  ++A + I  G+KV  ++Q E
Sbjct: 336  KFFELYEKDALLANALFDLKIAGGGRANMQLAGIPEMSFEYWAAQFIQMGYKVAKVDQRE 395

Query: 488  TPKELEQRNKESIGPKDKAIKREINEIYTKGTILHDNMLSAETKYLVCFYFDEIENMTNV 547
            +    E R     G K   +KRE+  I T GT+   +ML ++         +E  N    
Sbjct: 396  SMLAKEMRE----GSKG-IVKRELQCILTSGTLTDGDMLHSDLATFCLAIREEPGNF--- 447

Query: 548  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYTFSQYDNKN---KCN---FG 601
                                                   Y  +Q D+     K N   FG
Sbjct: 448  ---------------------------------------YNETQLDSSTIVQKLNTKIFG 468

Query: 602  FVVSDIATSYIAVGYCNDDESRIVLRTILAQLCPAEILYSSKNI----------NKEVLS 651
                D AT  + +    DD     L T+++Q+ P E++    N+          N    +
Sbjct: 469  AAFIDTATGELQMLEFEDDSECTKLDTLMSQVRPMEVVMERNNLSTLANKIVKFNSAPNA 528

Query: 652  IFKNIPTSPEL-TCLNSFPNIISSFDEINKYF---ENMPSNLEIYKEQTSVI--CAFGGF 705
            IF  +    E   C  ++  IISS     +YF   E+ P  L+ Y +    +   AFGG 
Sbjct: 529  IFNEVKAGEEFYDCDKTYAEIISS-----EYFSTEEDWPEVLKSYYDTGKKVGFSAFGGL 583

Query: 706  IVYLRSLLLDKKIFRFCKIEKYDLFKRETYMVLDATALKHLEILETQ-SGDTKNSLYDYV 764
            + YL+ L LDK +     I++YD  K +  MVLD   L++LEI      G  K +L+   
Sbjct: 584  LYYLKWLKLDKNLISMKNIKEYDFVKSQHSMVLDGITLQNLEIFSNSFDGSDKGTLFKLF 643

Query: 765  NKTCTNFGARNLRRWICSPLLDCEKIRERLDVVDFLKNNEQILSLIRMKLKKLPDIERLL 824
            N+  T  G R +++W+  PLL    I  RLD VD L  +  +   + +   KLPD+ER+L
Sbjct: 644  NRAITPMGKRMMKKWLMHPLLRKNDIESRLDSVDSLLQDITLREQLEITFSKLPDLERML 703

Query: 825  NKICIQASQSERGAVFFDNVVNTKLKEFVTFLNAFKEIDTMLIDVNRIERDGELPSRLFQ 884
             +I  +                 K+K+F   + AF+ I  +   +   +  G++      
Sbjct: 704  ARIHSRT---------------IKVKDFEKVITAFETIIELQDSLKNNDLKGDVSK---Y 745

Query: 885  ICNTPDICKDNIKGSYPNIGLITNEFLEKIYFDGDKEYKPAEGCDEDIDKIXXXXXXXXX 944
            I + P+   + +K         TN F E+     +    P  G D + DK          
Sbjct: 746  ISSFPEGLVEAVKSW-------TNAF-ERQKAINENIIVPQRGFDIEFDKSMDRIQELED 797

Query: 945  XXXXXXXHMRTQLKIPTLKFVHA-KFKYEVECPDNIPKSFLKNVEITSAKKGYVRIHNDE 1003
                     R Q K   +++  + K  Y +E P +  K+   N    +A K Y R ++DE
Sbjct: 798  ELMEILMTYRKQFKCSNIQYKDSGKEIYTIEIPISATKNVPSNWVQMAANKTYKRYYSDE 857

Query: 1004 IKSLVEKLEDIEQEKKDAIYPFFQKLFHLFYAHYEK-YVSACRLVAELDCLQSFAYVVLN 1062
            +++L   + + ++  K        +L   F AHY   ++   + ++ +DCL +       
Sbjct: 858  VRALARSMAEAKEIHKTLEEDLKNRLCQKFDAHYNTIWMPTIQAISNIDCLLAITRTSEY 917

Query: 1063 TAFPLTRP-ILHPMDSKQGEEKTPFLILEDNIHPVV---AMLMPNFISNNIYMGCDKEKQ 1118
               P  RP I+  +DSK   +   FL  +   HP     A    +FI N+I +G  KE+ 
Sbjct: 918  LGAPSCRPTIVDEVDSKTNTQLNGFLKFKSLRHPCFNLGATTAKDFIPNDIELG--KEQP 975

Query: 1119 STLLLTGPNMGGKSTLLRQTAISVILAQIGAFVPCTYCELTVVDKIFTRLGSSDNLFEGK 1178
               LLTG N  GKST+LR   I+VI+AQ+G +VPC    LT +D+I TRLG++DN+ +GK
Sbjct: 976  RLGLLTGANAAGKSTILRMACIAVIMAQMGCYVPCESAVLTPIDRIMTRLGANDNIMQGK 1035

Query: 1179 STFLVELEDISNLLKQSTKYSLAILDELGRGTSSFDGTAIALSTLEQISDVIKCRCIFST 1238
            STF VEL +   +L  +T  SL ++DELGRG SS DG AIA S L  ++  I+    F+T
Sbjct: 1036 STFFVELAETKKILDMATNRSLLVVDELGRGGSSSDGFAIAESVLHHVATHIQSLGFFAT 1095

Query: 1239 HYHLLVEEVKHNKNISNYHMSLSIDDEQEKIIFLYKFIKGVCPKSFGIHIAKLAGLPKEI 1298
            HY  L    KH+  +    MS+ +D+    + FLYK ++G    SFG+H+A + G+ KEI
Sbjct: 1096 HYGTLASSFKHHPQVRPLKMSILVDEATRNVTFLYKMLEGQSEGSFGMHVASMCGISKEI 1155

Query: 1299 IDLAHEKSLLFENVTDEFCKIIKYKNITRSLLNEE 1333
            ID A   +   E+ +    +++K +++  + LN E
Sbjct: 1156 IDNAQIAADNLEHTS----RLVKERDLAANNLNGE 1186

 Score = 20.0 bits (40), Expect = 1.5
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 7  KQSSILSFF 15
          KQSS+LSFF
Sbjct: 26 KQSSLLSFF 34

 Score = 18.5 bits (36), Expect = 4.3
 Identities = 9/33 (27%), Positives = 16/33 (48%)

Query: 1047 VAELDCLQSFAYVVLNTAFPLTRPILHPMDSKQ 1079
            +AE    + F+Y   +++ P TR I      K+
Sbjct: 210  LAETTSKKKFSYNTSHSSSPFTRNISRDNSKKK 242

Lambda     K      H
   0.318    0.136    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 3451
Number of extensions: 154
Number of successful extensions: 12
Number of sequences better than 10.0: 1
Number of HSP's gapped: 4
Number of HSP's successfully gapped: 4
Length of query: 1350
Length of database: 1242
Length adjustment: 48
Effective length of query: 1302
Effective length of database: 1194
Effective search space:  1554588
Effective search space used:  1554588
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 33 (18.0 bits)
S2: 33 (17.3 bits)