>YMR308C PSE1 SGDID:S000004925, Chr XIII from 892220-888951, reverse
            complement, Verified ORF, "Karyopherin/importin that
            interacts with the nuclear pore complex; acts as the
            nuclear import receptor for specific proteins, including
            Pdr1p, Yap1p, Ste12p, and Aft1p"
          Length = 1089

 Score =  264 bits (674), Expect = 3e-74
 Identities = 249/1105 (22%), Positives = 498/1105 (45%), Gaps = 78/1105 (7%)

Query: 4    IVEVIEGLSSSESHIRNECENTLN--YYKKNDLNNTVLSILKLLKTHKDSQVRLQCAILI 61
            ++++++  +S ++ IR+  E  L+  +  +N++   +  + +     +D+ V    A+L 
Sbjct: 12   LLQIVQAFASPDNQIRSVAEKALSEEWITENNIEYLLTFLAEQAAFSQDTTVAALSAVLF 71

Query: 62   RNIFRVYIKSTHVDVEEKEKNENSIGNAEEENYWVLLPDNLKNIVKSELISNIGTETDKM 121
            R +      S+ + +  K     +I +  +E   VL        ++S L+    +E    
Sbjct: 72   RKLALKAPPSSKLMIMSK-----NITHIRKE---VLAQ------IRSSLLKGFLSERADS 117

Query: 122  VRSNICNNIIDLSSKLLLHNQWPELLSVTFEFCNSNNVDVLISGYKILGGILSCIPDELD 181
            +R  + + I +     L    WPELL    E   S N +   S ++IL    + +P  + 
Sbjct: 118  IRHKLSDAIAECVQDDL--PAWPELLQALIESLKSGNPNFRESSFRIL----TTVPYLIT 171

Query: 182  GKQ-EIISSICMKGLNSSNVQVRGECINLISCIVEDNSSSLVKSVHGCIPLILQSLSLMA 240
                  I  I   G   ++  V+   +       +    S    +   +P +L SL    
Sbjct: 172  AVDINSILPIFQSGFTDASDNVKIAAVTAFVGYFKQLPKSEWSKLGILLPSLLNSLPRFL 231

Query: 241  KNSSSDIAVLEECEKVLQSIGKMIDYNAKFFTKHITSLCDILFSICMKDENELNYDFDNS 300
             +   D         V +S+ ++++   K F      +      I   D    N D +  
Sbjct: 232  DDGKDDALA-----SVFESLIELVELAPKLFKDMFDQI------IQFTDMVIKNKDLEPP 280

Query: 301  LKSLSIEALVTIPERRPKMALSVPHFVDKIIHLSMLFMLD--INNDCFNEWMNSIKEGKD 358
             ++ ++E L    E  P+M  S  ++   ++ ++++ M +  I++D   EW+ S  +  D
Sbjct: 281  ARTTALELLTVFSENAPQMCKSNQNYGQTLVMVTLIMMTEVSIDDDDAAEWIES--DDTD 338

Query: 359  DSQEL-YDIGEESLDRVGKAFSELEEAEFIHI-LFNKVSEFLMKNTWEHKYVGIMAIAQT 416
            D +E+ YD   ++LDRV          E++   LF  + + +    W  ++  +MA++  
Sbjct: 339  DEEEVTYDHARQALDRVALKLG----GEYLAAPLFQYLQQMITSTEWRERFAAMMALSSA 394

Query: 417  IEYLPEDEIEEQLEHVIKMLLQILVDQDVRVRYAACQAIGQISLDHQPYVQKEFFSEILS 476
             E   +  I E +  ++ M++ ++ D   RV+Y  C  +GQIS D  P++Q+     IL 
Sbjct: 395  AEGCADVLIGE-IPKILDMVIPLINDPHPRVQYGCCNVLGQISTDFSPFIQRTAHDRILP 453

Query: 477  ALINTM-NDVHLRVQSHATAAFVNYAEELDKMALLPYADIIIDILLQKLNSSNYLLVREQ 535
            ALI+ + ++   RVQ+HA AA VN++E   K  L PY D ++  LL  L S N L V+EQ
Sbjct: 454  ALISKLTSECTSRVQTHAAAALVNFSEFASKDILEPYLDSLLTNLLVLLQS-NKLYVQEQ 512

Query: 536  XXXXXXXXXXXXEEDFLKYYSTVVPMMKDIIQKAVSEEERTCRGKAIECISIIGLSVGKD 595
                        +  F+KYY T++P++ +++ K  +++    +GK +EC ++IG +VGK+
Sbjct: 513  ALTTIAFIAEAAKNKFIKYYDTLMPLLLNVL-KVNNKDNSVLKGKCMECATLIGFAVGKE 571

Query: 596  IFIEDAKECMNALLQISSTKMDPDDTVKEYIQEAIGRICRALGNDFYPYLSSIVPTIL-S 654
             F E ++E ++ L+ + ++ +D DD ++ Y++++  RICR LG+DF P L  ++P +L +
Sbjct: 572  KFHEHSQELISILVALQNSDIDEDDALRSYLEQSWSRICRILGDDFVPLLPIVIPPLLIT 631

Query: 655  VLSVLPKPLTDDEE--------DLTITMVSNGQYVGLKTSLLEDQEKALDLLIIIIEVLK 706
              +     L ++EE        D  +  V  G+++ + TS+L+D+  A++LL     +L+
Sbjct: 632  AKATQDVGLIEEEEAANFQQYPDWDVVQV-QGKHIAIHTSVLDDKVSAMELLQSYATLLR 690

Query: 707  ENYKDYIQATATAV-LPMLNYELSDEIKQKALTAVSELIESARILSEKTDNDKSMLLAIL 765
              +  Y++     + LP L++ L D ++    T +  L+ S  + +  T N++ +LL   
Sbjct: 691  GQFAVYVKEVMEEIALPSLDFYLHDGVRAAGATLIPILL-SCLLAATGTQNEELVLL--W 747

Query: 766  TAAAEKVLKSLLETKLDDNYEYILDVMIIESHGLYMCLQKAGSNVLPENTLKLFFNQIFA 825
              A+ K++  L+        E + ++  +  + L   ++  G N L E+ L  F   + A
Sbjct: 748  HKASSKLIGGLMS-------EPMPEITQVYHNSLVNGIKVMGDNCLSEDQLAAFTKGVSA 800

Query: 826  LLQYSTDRRVVYNQKKNNXXXXXXXXXXXXXXXXXXQNYRTNLLDILGVLIKYHPTQFLN 885
             L  + +R      +  +                  ++    +   +  ++K     +L 
Sbjct: 801  NLTDTYER-----MQDRHGDGDEYNENIDEEEDFTDEDLLDEINKSIAAVLKTTNGHYLK 855

Query: 886  TCCELCIGFINNYMNSPNSEDVALALYVCDDLLEFLQEKSVNLWDFFMNPLLLNINHADD 945
               E     IN ++       V  AL V  DL+++  E++ ++ + F+  +   +   D 
Sbjct: 856  N-LENIWPMINTFLLDNEPILVIFALVVIGDLIQYGGEQTASMKNAFIPKVTECLISPDA 914

Query: 946  KVKQAACYGVIQATKIEAFGKYANIAVEYLLKLVH-ESTSNKKPKEYISAIDNAIAALGD 1004
            +++QAA Y +I      A   YA++ +  L  LV        K +E  S+ +NA AA+  
Sbjct: 915  RIRQAASY-IIGVCAQYAPSTYADVCIPTLDTLVQIVDFPGSKLEENRSSTENASAAIAK 973

Query: 1005 VVLMHTSKFNNAEDLIKVWLNHLPIKEDDAEGRRVHKNLIDLVSQNHPLLFGKDNSNTAK 1064
            ++  + S   N +     W   LP   D       ++ L  L+  N P++  + N  +A 
Sbjct: 974  ILYAYNSNIPNVDTYTANWFKTLPTITDKEAASFNYQFLSQLIENNSPIVCAQSNI-SAV 1032

Query: 1065 IIEIFLTIYETDFSDTDCNKKISTL 1089
            +  +   + E   ++ +    IS++
Sbjct: 1033 VDSVIQALNERSLTEREGQTVISSV 1057

 Score = 23.9 bits (50), Expect = 0.073
 Identities = 12/32 (37%), Positives = 18/32 (56%), Gaps = 4/32 (12%)

Query: 1074 ETDFSDTDC----NKKISTLINSLDKSYLNNL 1101
            E DF+D D     NK I+ ++ + +  YL NL
Sbjct: 826  EEDFTDEDLLDEINKSIAAVLKTTNGHYLKNL 857

 Score = 19.6 bits (39), Expect = 1.4
 Identities = 8/29 (27%), Positives = 15/29 (51%)

Query: 602 KECMNALLQISSTKMDPDDTVKEYIQEAI 630
           +E    LLQI      PD+ ++   ++A+
Sbjct: 6   EEVNRTLLQIVQAFASPDNQIRSVAEKAL 34

Lambda     K      H
   0.318    0.134    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 2615
Number of extensions: 130
Number of successful extensions: 20
Number of sequences better than 10.0: 1
Number of HSP's gapped: 7
Number of HSP's successfully gapped: 7
Length of query: 1123
Length of database: 1089
Length adjustment: 46
Effective length of query: 1077
Effective length of database: 1043
Effective search space:  1123311
Effective search space used:  1123311
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 32 (17.6 bits)
S2: 32 (16.9 bits)