>YDL058W USO1 SGDID:S000002216, Chr IV from 345665-351037, Verified
            ORF, "Essential protein involved in intracellular protein
            transport, coiled-coil protein necessary for transport
            from ER to Golgi; required for assembly of the
            ER-to-Golgi SNARE complex"
          Length = 1790

 Score = 46.6 bits (109), Expect = 3e-08
 Identities = 60/218 (27%), Positives = 92/218 (42%), Gaps = 20/218 (9%)

Query: 1001 KFYENILKNNDTYFNDDIKQFVKSNSKVITGLTETQKNALNDEIKKLKDTLQLSFDLYNK 1060
            K YE  + N +  +N++I Q    N ++    T TQ+   N+ IKK  D L+        
Sbjct: 1162 KKYEEQIANKERQYNEEISQL---NDEI----TSTQQE--NESIKKKNDELEGEVKAMKS 1212

Query: 1061 YKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLE-SKLNSLNNPHNVLQNFSVFFNKK--K 1117
               +   L  KK E+    +QIK+L    E  E S L S+ +  +         ++   K
Sbjct: 1213 TSEEQSNL--KKSEIDALNLQIKELKKKNETNEASLLESIKSVESETVKIKELQDECNFK 1270

Query: 1118 EAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSK 1177
            E E++E E+ L+ ++     Y  L K    ES  +K   E+  +T +    LEK   LSK
Sbjct: 1271 EKEVSELEDKLKASEDKNSKYLELQK----ESEKIK--EELDAKTTELKIQLEKITNLSK 1324

Query: 1178 IDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKN 1215
               K    L   KK  S         + +LK  I+ KN
Sbjct: 1325 AKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKN 1362

 Score = 40.4 bits (93), Expect = 2e-06
 Identities = 61/291 (20%), Positives = 123/291 (42%), Gaps = 25/291 (8%)

Query: 987  KVPNPLTISTTEMEKFYENI--LKNNDTYFNDDIKQFVKSNSKVITGLTETQKNALNDEI 1044
            K+   L   TTE++   E I  L         ++ +  K++S       E +KNA  +++
Sbjct: 1300 KIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSS-------EERKNA-EEQL 1351

Query: 1045 KKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNS--LNNP 1102
            +KLK+ +Q+    + K +  L+   +   +   +K+   +  L++ Q E++L +  ++N 
Sbjct: 1352 EKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNT 1411

Query: 1103 HNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQT 1162
             + L+  S+      +  + E +NT+++ +  +  YK  +   N E         +SI+ 
Sbjct: 1412 RSELEKVSL----SNDELLEEKQNTIKSLQDEILSYKDKITR-NDEKL-------LSIE- 1458

Query: 1163 EDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNYTGNSPS 1222
             DN  +LE  +   +   +    +  G KKL   SS     + + KE++K    T  S  
Sbjct: 1459 RDNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNE 1518

Query: 1223 ENNKKVNEALKSYENFLPEAKXXXXXXXXXXXXXXSPLSVRVSGSSGSTKE 1273
               K   E ++  +  L ++K              S L  R++ S    +E
Sbjct: 1519 TELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEE 1569

 Score = 37.4 bits (85), Expect = 2e-05
 Identities = 124/603 (20%), Positives = 221/603 (36%), Gaps = 111/603 (18%)

Query: 994  ISTTEMEKFYENILKNNDTYFNDDIKQFVKSNSKVITGLTETQKNALNDEIKKLKDTLQL 1053
            IS  E+EK     L+   T    +I             LTE +  AL +E K+L +  Q+
Sbjct: 727  ISFEEVEK-----LQRQCTKLKGEITSLQTETESTHENLTE-KLIALTNEHKELDEKYQI 780

Query: 1054 SFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNPHNVLQNFSVFF 1113
                ++  K     L   + EL   +  + ++T L++ LE+K     N   +L+  S   
Sbjct: 781  LNSSHSSLKENFSIL---ETELKNVRDSLDEMTQLRDVLETK--DKENQTALLEYKSTIH 835

Query: 1114 NKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFR 1173
              K+E  I   E  LE    +L   K      N     L  LS      E+N  NL+K +
Sbjct: 836  --KQEDSIKTLEKGLET---ILSQKKKAEDGINKMGKDLFALSREMQAVEENCKNLQKEK 890

Query: 1174 VLSKIDGK-------------------LNDNLHLGKKKLSFLSSGLHHLITELKEVIKNK 1214
              S ++ +                   +N+NL   K + + LS    H+  EL E     
Sbjct: 891  DKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKELVE----- 945

Query: 1215 NYTGNSPSENN--KKVNEALKSYENFLPEAKXXXXXXXXXXXXXXSPLSVRVSGSSGSTK 1272
             Y     S +N   K+ E LKS  N   + +              +  S+++S       
Sbjct: 946  -YKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKID 1004

Query: 1273 EETQIPTSGSXXXXXXXXXXXXNYDEEDDSLVVLPIFGESEDNDEYLDQVVTGEAISVTM 1332
              +Q                  N+  E  S+         E N E L + ++   +  T 
Sbjct: 1005 SMSQ---------------EKENFQIERGSI---------EKNIEQLKKTISD--LEQTK 1038

Query: 1333 DNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLE 1392
            + I+S  ++  D  Y   ++     LK+++E      + N+N I  S L K +   + LE
Sbjct: 1039 EEIISKSDSSKDE-YESQIS----LLKEKLETATTANDENVNKI--SELTKTR---EELE 1088

Query: 1393 SDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVL 1452
            ++L  +K+              L +E +  L  S K +KE  EN+    +E I   EK  
Sbjct: 1089 AELAAYKN--------------LKNELETKLETSEKALKEVKENEEHLKEEKIQL-EKEA 1133

Query: 1453 AKYKDDLXXXXXXXXXXXXXFXXXXXXXXXXXAKTDEQKKESKFLPFLTNIETLYNNLVN 1512
             + K  L                            D   +  K+   + N E  YN  ++
Sbjct: 1134 TETKQQLNSLRANLESLEKEHE-------------DLAAQLKKYEEQIANKERQYNEEIS 1180

Query: 1513 KIDDYLINLKAKINDCNVEKDEAHVKITKLSDLKAIDDKIDLFKNPYDFEAIKKLINDDT 1572
            +++D + + + +      + DE   ++  +      +++ +L K+  + +A+   I +  
Sbjct: 1181 QLNDEITSTQQENESIKKKNDELEGEVKAMKSTS--EEQSNLKKS--EIDALNLQIKELK 1236

Query: 1573 KKD 1575
            KK+
Sbjct: 1237 KKN 1239

 Score = 35.4 bits (80), Expect = 6e-05
 Identities = 23/97 (23%), Positives = 48/97 (49%)

Query: 243  LDNIKDNVGKMEDYIKKNKTTIANINELIEGSKKTIDQNKNADNEEGKKKLYQAQYDLSI 302
            L+  K+ + K+E  I+ N+T + +  E I  S + ++Q+K +  E+ K   ++    +S 
Sbjct: 1500 LEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISR 1559

Query: 303  YNKQLEEAHNLISVLEKRIDTLKKNENIKKLLDKINE 339
             N+  ++   L S L     +  + E +K+ L+   E
Sbjct: 1560 INESEKDIEELKSKLRIEAKSGSELETVKQELNNAQE 1596

 Score = 35.0 bits (79), Expect = 8e-05
 Identities = 108/495 (21%), Positives = 178/495 (35%), Gaps = 115/495 (23%)

Query: 986  TKVPNPLTISTTEMEKFYENILKNNDTYFNDDIKQFVKSNSKVITGLTETQKNALNDEIK 1045
            TK+   +T   TE E  +EN+                    K+I         AL +E K
Sbjct: 740  TKLKGEITSLQTETESTHENL------------------TEKLI---------ALTNEHK 772

Query: 1046 KLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNPHNV 1105
            +L +  Q+    ++  K     L   + EL   +  + ++T L++ LE+K     N   +
Sbjct: 773  ELDEKYQILNSSHSSLKENFSIL---ETELKNVRDSLDEMTQLRDVLETK--DKENQTAL 827

Query: 1106 LQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDN 1165
            L+  S     K+E  I   E  LE    +L   K      N     L  LS      E+N
Sbjct: 828  LEYKSTI--HKQEDSIKTLEKGLET---ILSQKKKAEDGINKMGKDLFALSREMQAVEEN 882

Query: 1166 YANLEKFRVLSKIDGK-------------------LNDNLHLGKKKLSFLSSGLHHLITE 1206
              NL+K +  S ++ +                   +N+NL   K + + LS    H+  E
Sbjct: 883  CKNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKE 942

Query: 1207 LKEVIKNKNYTGNSPSENN--KKVNEALKSYENFLPEAKXXXXXXXXXXXXXXSPLSVRV 1264
            L E      Y     S +N   K+ E LKS  N   + +                 +  +
Sbjct: 943  LVE------YKSRFQSHDNLVAKLTEKLKSLANNYKDMQAE---------------NESL 981

Query: 1265 SGSSGSTKEETQIPTSGSXXXXXXXXXXXXNYDEEDDSLVVLPIFGESEDNDEYLDQVVT 1324
              +   +K E+ I  S              N+  E  S+         E N E L + ++
Sbjct: 982  IKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSI---------EKNIEQLKKTIS 1032

Query: 1325 GEAISVTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKR 1384
               +  T + I+S  ++  D             LK+++E      + N+N I  S L K 
Sbjct: 1033 D--LEQTKEEIISKSDSSKD-----EYESQISLLKEKLETATTANDENVNKI--SELTKT 1083

Query: 1385 KYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEG 1444
            +   + LE++L  +K+              L +E +  L  S K +KE  EN+    +E 
Sbjct: 1084 R---EELEAELAAYKN--------------LKNELETKLETSEKALKEVKENEEHLKEEK 1126

Query: 1445 ISYYEKVLAKYKDDL 1459
            I   EK   + K  L
Sbjct: 1127 IQ-LEKEATETKQQL 1140

 Score = 34.3 bits (77), Expect = 1e-04
 Identities = 98/498 (19%), Positives = 191/498 (38%), Gaps = 45/498 (9%)

Query: 983  GNKTKVPNPLTISTTEMEKFYENILKNNDTYFNDDIKQFVKSNSKVITGLTETQKNALN- 1041
            G+  K    L  + +++E+  E I+  +D+  ++   Q      K+ T  T   +N    
Sbjct: 1018 GSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTANDENVNKI 1077

Query: 1042 DEIKKLKDTLQLSFDLYNKYKLKLD-RLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLN 1100
             E+ K ++ L+     Y   K +L+ +L   +K L + K   + L   K QLE +     
Sbjct: 1078 SELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATETK 1137

Query: 1101 NPHNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLV----KYYNGESSPLKTLS 1156
               N L+           A +   E   E+    LK Y+  +    + YN E S L    
Sbjct: 1138 QQLNSLR-----------ANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLN--D 1184

Query: 1157 EVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHHLITELKEVIKNKNY 1216
            E++   ++N +  +K     +++G++       +++ +   S +  L  ++KE+ K    
Sbjct: 1185 EITSTQQENESIKKKN---DELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNET 1241

Query: 1217 TGNSPSENNKKV-NEALKSYE-----NFLPEAKXXXXXXXXXXXXXXSPLSVRVSGSSGS 1270
               S  E+ K V +E +K  E     NF  E +              +   + +   S  
Sbjct: 1242 NEASLLESIKSVESETVKIKELQDECNF-KEKEVSELEDKLKASEDKNSKYLELQKESEK 1300

Query: 1271 TKEETQIPTSGSXXXXXXXXXXXXNYDEEDDSLVVLPIFGESE--DNDEYLDQVVTGEAI 1328
             KEE    T+                ++ +  L  L      E  + +E L+++     I
Sbjct: 1301 IKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQI 1360

Query: 1329 SVTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFL 1388
                        NE      +  +    +L+ ++ +      L   +I N+R +  K  L
Sbjct: 1361 KNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSL 1420

Query: 1389 ---DVLESDL-----MQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKF 1440
               ++LE        +Q + +S  + I  +  KLL+ E+ N      K   ES++  ++ 
Sbjct: 1421 SNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDN------KRDLESLKEQLRA 1474

Query: 1441 AQEGISYYEKVLAKYKDD 1458
            AQE  +  E+ L K +++
Sbjct: 1475 AQESKAKVEEGLKKLEEE 1492

 Score = 33.9 bits (76), Expect = 2e-04
 Identities = 56/265 (21%), Positives = 102/265 (38%), Gaps = 50/265 (18%)

Query: 987  KVPNPLTISTTEMEKFYENILKNNDTY------FNDDIKQFVKSNSKVITGLTETQKN-- 1038
            K+ + +  + TE++   E I K+++          +DIK      S +I+ + E++K+  
Sbjct: 1509 KLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIE 1568

Query: 1039 -----------------ALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQ 1081
                              +  E+   ++ ++++ +     K KL+ +   ++EL   + +
Sbjct: 1569 ELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKSKLEDI---ERELKDKQAE 1625

Query: 1082 IKKLTLLKEQLESKLNSLNNPHNVLQNFSVFFNKKKEAEI----AETENTLENTKILLKH 1137
            IK     KE L S+L  L    +  Q  +    +++ AE+     E     E   +L   
Sbjct: 1626 IKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERRAEVRKFQVEKSQLDEKAMLLETK 1685

Query: 1138 YKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLS 1197
            Y  LV   N E +  +    V   T+     +EK         K  DNL     KL   +
Sbjct: 1686 YNDLV---NKEQAWKRDEDTVKKTTDSQRQEIEKL-------AKELDNLKAENSKLKEAN 1735

Query: 1198 ------SGLHHLITELKEVIKNKNY 1216
                    L  L+T+L E  KN  Y
Sbjct: 1736 EDRSEIDDLMLLVTDLDE--KNAKY 1758

 Score = 29.6 bits (65), Expect = 0.003
 Identities = 26/105 (24%), Positives = 52/105 (49%), Gaps = 10/105 (9%)

Query: 241  KPLDNIKDNVGKMEDYIKKNKTTIANINELIEGSKKTIDQNKNADNEEGKKKLYQAQ--- 297
            K L  +K+N    E+++K+ K  +    E  E  ++      N ++ E + +   AQ   
Sbjct: 1110 KALKEVKEN----EEHLKEEKIQLEK--EATETKQQLNSLRANLESLEKEHEDLAAQLKK 1163

Query: 298  YDLSIYNKQLEEAHNLISVLEKRIDTLKKNENIKKLLDKI-NEIK 341
            Y+  I NK+ +    +  + ++   T ++NE+IKK  D++  E+K
Sbjct: 1164 YEEQIANKERQYNEEISQLNDEITSTQQENESIKKKNDELEGEVK 1208

 Score = 28.5 bits (62), Expect = 0.008
 Identities = 21/114 (18%), Positives = 52/114 (45%), Gaps = 10/114 (8%)

Query: 228  ELDVLKKLVFGYRKPLDNIKDNVGKMEDYIKKNKTTIANINELIEGSKKTIDQNK----- 282
            +L+ LK+ +   ++    +++ + K+E+   K K  +    E+++  + TI+ N+     
Sbjct: 1464 DLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKS 1523

Query: 283  -----NADNEEGKKKLYQAQYDLSIYNKQLEEAHNLISVLEKRIDTLKKNENIK 331
                    +E+ ++    A+ D+     +  +  + I+  EK I+ LK    I+
Sbjct: 1524 SMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIE 1577

 Score = 25.8 bits (55), Expect = 0.050
 Identities = 174/935 (18%), Positives = 348/935 (37%), Gaps = 140/935 (14%)

Query: 560  NVQKLKKALSYLEDYSLRKGISEKDFNHYYTLKTGLEADIKKLTEEIKSSENKILEKNFK 619
            N+ +++ ALS+  D      IS ++        T L+ +I  L  E +S+   + EK   
Sbjct: 707  NIYRIRTALSHDPDEEPINKISFEEVEKLQRQCTKLKGEITSLQTETESTHENLTEK--- 763

Query: 620  GLTHSANGSLEVSDXXXXXXXXXXXXXXXEDLRKIELFLKNAQ--LKDSIHVPNIYKPQN 677
             L    N   E+ +               E+   +E  LKN +  L +   + ++ + ++
Sbjct: 764  -LIALTNEHKELDEKYQILNSSHSSLK--ENFSILETELKNVRDSLDEMTQLRDVLETKD 820

Query: 678  KPEPYYLIVLKKEVDKLKEFIPKVKDMLKKEQAVLSSITQPLVAASETTEDGGHSTHTLS 737
            K     L+       + K  I K +D +K  +  L +I      A +     G     LS
Sbjct: 821  KENQTALL-------EYKSTIHKQEDSIKTLEKGLETILSQKKKAEDGINKMGKDLFALS 873

Query: 738  QSGXXXXXXXXXXXXXXXXXXXXXXXXLPPTQPSPPKEVKVVENSIEH------KSNDNS 791
                                                +E++ VE + ++      KSN N 
Sbjct: 874  ------------------------------------REMQAVEENCKNLQKEKDKSNVNH 897

Query: 792  QALTKTVYLKKLDEFLTKSYICHKY--ILVSNSSMDQKLLEVYNLTPEEENELKSCDPLD 849
            Q  TK++          K  I  K   I   N ++++  ++  NL+ E+E+  K      
Sbjct: 898  QKETKSL----------KEDIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKELVEYK 947

Query: 850  LLFNIQNNIPA-MYSLYDSMNNDLQHLFFELYQKEMIYYLHKLKEENHIKKLLEEQKQIX 908
              F   +N+ A +     S+ N+ + +  E   + +I  + + K E+ I +L   Q +I 
Sbjct: 948  SRFQSHDNLVAKLTEKLKSLANNYKDMQAE--NESLIKAVEESKNESSI-QLSNLQNKID 1004

Query: 909  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGVAVSSGPAVVEESHDPLTVLS 968
                                                    + SS     ++ ++  + +S
Sbjct: 1005 SMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSS-----KDEYE--SQIS 1057

Query: 969  ISNDLKGIVSLLNLGNKTKVPNPLTISTTEME---KFYENILKNNDTYFNDDIKQFVKSN 1025
            +  +     +  N  N  K+ + LT +  E+E     Y+N LKN       +++  ++++
Sbjct: 1058 LLKEKLETATTANDENVNKI-SELTKTREELEAELAAYKN-LKN-------ELETKLETS 1108

Query: 1026 SKVITGLTETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKEL-GQDKMQIKK 1084
             K +  + E +++   ++I+  K+  +    L N  +  L+ L  + ++L  Q K   ++
Sbjct: 1109 EKALKEVKENEEHLKEEKIQLEKEATETKQQL-NSLRANLESLEKEHEDLAAQLKKYEEQ 1167

Query: 1085 LTLLKEQLESKLNSLNNPHNVLQNFSVFFNKKK---EAEIAETENTLENTKILLK----- 1136
            +   + Q   +++ LN+     Q  +    KK    E E+   ++T E    L K     
Sbjct: 1168 IANKERQYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDA 1227

Query: 1137 ---HYKGL-VKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKK 1192
                 K L  K    E+S L+++  V  +T       ++     K   +L D L   + K
Sbjct: 1228 LNLQIKELKKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDK 1287

Query: 1193 LS-FLSSGLHHLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLPEAKXXXXXXXX 1251
             S +L   L     ++KE +  K        E    +++A +  E+ L   K        
Sbjct: 1288 NSKYLE--LQKESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERK 1345

Query: 1252 XXXXXXSPLSVRVSGSSGSTKEETQIPTSGSXXXXXXXXXXXXNYDEEDDSLVVLPIFGE 1311
                    L   +   + + ++E ++   GS              ++E     ++ +  E
Sbjct: 1346 NAEEQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDE-----LIRLQNE 1400

Query: 1312 SEDNDEYLDQVVTG-EAISVTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFN 1370
            +E   + +D   +  E +S++ D +L   +N      +K L     S K +I +N     
Sbjct: 1401 NELKAKEIDNTRSELEKVSLSNDELLEEKQNT-----IKSLQDEILSYKDKITRN----- 1450

Query: 1371 LNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLL---NSEQKNTLLKSY 1427
               ++ L S  +  K  L+ L+    Q +    ++  +E+  K L   +S++K  L KS 
Sbjct: 1451 ---DEKLLSIERDNKRDLESLKE---QLRAAQESKAKVEEGLKKLEEESSKEKAELEKSK 1504

Query: 1428 KYIK------ESVENDIKFAQEGISYYEKVLAKYK 1456
            + +K      ES E ++K + E I   ++ L + K
Sbjct: 1505 EMMKKLESTIESNETELKSSMETIRKSDEKLEQSK 1539

 Score = 24.3 bits (51), Expect = 0.14
 Identities = 24/112 (21%), Positives = 51/112 (45%), Gaps = 8/112 (7%)

Query: 228  ELDVLKKLVFGYRKPLDNIKDNVGKMEDYIKKNKTTIANINELIEGSKKTIDQNKNADNE 287
            +L  L+  +    +  +N +   G +E  I++ K TI+++    E +K+ I    ++  +
Sbjct: 995  QLSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDL----EQTKEEIISKSDSSKD 1050

Query: 288  EGKKKLYQAQYDLSIYNKQLEEAHNLISVLEKRIDTLKKN----ENIKKLLD 335
            E + ++   +  L       +E  N IS L K  + L+      +N+K  L+
Sbjct: 1051 EYESQISLLKEKLETATTANDENVNKISELTKTREELEAELAAYKNLKNELE 1102

 Score = 22.7 bits (47), Expect = 0.42
 Identities = 11/37 (29%), Positives = 20/37 (54%)

Query: 23   ESYQELVKKLEALEDAVLTGYSLFQKEKMVLNEEEIT 59
            E  +   ++LE L++ +      F+KE+ +LNE   T
Sbjct: 1342 EERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSST 1378

 Score = 21.2 bits (43), Expect = 1.2
 Identities = 11/40 (27%), Positives = 19/40 (47%)

Query: 1376 ILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLL 1415
            +L  +   R+Y   V+ S L    +    +Y+ EDS K +
Sbjct: 40   VLGLKAFSRQYRESVIASGLKPLLNTLKRDYMDEDSVKAI 79

 Score = 20.8 bits (42), Expect = 1.6
 Identities = 16/71 (22%), Positives = 33/71 (46%), Gaps = 6/71 (8%)

Query: 226  ANELDVLK------KLVFGYRKPLDNIKDNVGKMEDYIKKNKTTIANINELIEGSKKTID 279
            A ELD LK      K     R  +D++   V  +++   K ++ + ++   I   ++  +
Sbjct: 1718 AKELDNLKAENSKLKEANEDRSEIDDLMLLVTDLDEKNAKYRSKLKDLGVEISSDEEDDE 1777

Query: 280  QNKNADNEEGK 290
            ++   D EEG+
Sbjct: 1778 EDDEEDEEEGQ 1788

 Score = 20.0 bits (40), Expect = 2.7
 Identities = 7/30 (23%), Positives = 16/30 (53%)

Query: 286 NEEGKKKLYQAQYDLSIYNKQLEEAHNLIS 315
           +E G  K+Y + Y + ++N+ +      +S
Sbjct: 687 DETGLPKVYFSTYFIQLFNENIYRIRTALS 716

Lambda     K      H
   0.312    0.132    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 7463
Number of extensions: 464
Number of successful extensions: 35
Number of sequences better than 10.0: 1
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 1720
Length of database: 1790
Length adjustment: 53
Effective length of query: 1667
Effective length of database: 1737
Effective search space:  2895579
Effective search space used:  2895579
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 36 (19.1 bits)
S2: 36 (18.5 bits)