>YLR274W CDC46 SGDID:S000004264, Chr XII from 691557-693884,
           Verified ORF, "Component of the hexameric MCM complex,
           which is important for priming origins of DNA
           replication in G1 and becomes an active ATP-dependent
           helicase that promotes DNA melting and elongation when
           activated by Cdc7p-Dbf4p in S-phase"
          Length = 775

 Score =  140 bits (353), Expect = 3e-37
 Identities = 102/359 (28%), Positives = 170/359 (47%), Gaps = 51/359 (14%)

Query: 577 FYLLISSFCPRIIMNSYIK-AXXXXXXXXXKTIYDDNNQIKRRGNIHNLLIGDPGLGKSR 635
           + +L +S  P I  N  IK A         K I  D  ++  RG+I+ LL+GDPG  KS+
Sbjct: 367 YEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRL--RGDINVLLLGDPGTAKSQ 424

Query: 636 ILQYISNIMEKSLFICSTSTTINGLTACAVKDTTNNEYSLEGGALVLSDKGVCCIDELDK 695
           +L+++  +   +++     ++  GLTA   +D    E+ LEGGA+VL+D GV CIDE DK
Sbjct: 425 LLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDK 484

Query: 696 ISLNDQQSFLECMENQSINITKAGIVCNLKTRCTIIAASNP--KEADNISEEKDYHISNY 753
           +   D+ +  E ME Q+I+I KAGI   L +R +++AA+NP     D++    D      
Sbjct: 485 MRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQT 544

Query: 754 LINPNKNKNDLSEDDHTQHTDFQSDD---NSKEGSYNFSESDXXXXXXXXXXXXXXXXXX 810
            I    +   + +DDH +  D    +   N   G+ N  ++                   
Sbjct: 545 TILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQN------------------- 585

Query: 811 XXDYSPYIFSIKDALLYKCKQINEQNYLPLELIGVYIKYCRKYIFPKLSEDAKKYIRKFY 870
                              +Q    + + +E +  YI YCR    P+LS  A + +   +
Sbjct: 586 -------------------QQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNF 626

Query: 871 LHLR-----NLANTHNDISVPITIRQLESLIRLCQARARADLSHMVTLKHAKEVVEIYQ 924
           + +R     N   +    S+PITIRQLE++IR+ ++ A+ +LS +   +H  E + ++Q
Sbjct: 627 VTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQ 685

 Score = 40.4 bits (93), Expect = 5e-07
 Identities = 36/162 (22%), Positives = 69/162 (42%), Gaps = 33/162 (20%)

Query: 175 LKSEKVNQLICLRGSVLRVSPIQLLITNLNFVCDKCKCIIKVEFMD------GKFEPPKK 228
           L SE V++++ L G ++  S +    T L+ +C  C+    +   +           P+ 
Sbjct: 151 LDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNSITGNTVSLPRS 210

Query: 229 CMTN--------------------NCDGKQFLPIRESAKSLEYQKIILKENRKIVNNIYE 268
           C++                     NC    ++ I ES+K ++ Q + L+E  ++V  + E
Sbjct: 211 CLSTIESESSMANESNIGDESTKKNCGPDPYIIIHESSKFIDQQFLKLQEIPELVP-VGE 269

Query: 269 TNDTNIKNLTVTLEASKFFVNSCIPGNYVEALGILKVISFNN 310
                 +NLT+T +  ++  N  IPG  V  +GI  + +  N
Sbjct: 270 MP----RNLTMTCD--RYLTNKVIPGTRVTIVGIYSIYNSKN 305

 Score = 19.2 bits (38), Expect = 1.2
 Identities = 15/52 (28%), Positives = 23/52 (44%), Gaps = 3/52 (5%)

Query: 508 RDNVINMYGDYINEENDFNRNVHYIN---SSDEENENYHEKNRDNNSLHLNK 556
           R ++I +  D  NEE D +   H IN    +    +N  E+N    S+   K
Sbjct: 549 RFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMK 600

 Score = 16.9 bits (32), Expect = 5.7
 Identities = 6/10 (60%), Positives = 7/10 (70%)

Query: 124 DEIDKFGNED 133
           DE DK  +ED
Sbjct: 480 DEFDKMRDED 489

 Score = 16.2 bits (30), Expect = 9.8
 Identities = 8/37 (21%), Positives = 18/37 (48%)

Query: 988  LSADSNVTDEALIHFVNNEGFILYKGGYWQVDSFYLK 1024
            ++ +SN+ DE+       + +I+       +D  +LK
Sbjct: 221  MANESNIGDESTKKNCGPDPYIIIHESSKFIDQQFLK 257

Lambda     K      H
   0.318    0.135    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 1496
Number of extensions: 62
Number of successful extensions: 8
Number of sequences better than 10.0: 1
Number of HSP's gapped: 6
Number of HSP's successfully gapped: 6
Length of query: 1024
Length of database: 775
Length adjustment: 43
Effective length of query: 981
Effective length of database: 732
Effective search space:   718092
Effective search space used:   718092
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 30 (16.6 bits)
S2: 30 (16.2 bits)