>YKL210W UBA1 SGDID:S000001693, Chr XI from 39164-42238, Verified ORF,
            "Ubiquitin activating enzyme, involved in
            ubiquitin-mediated protein degradation and essential for
            viability"
          Length = 1024

 Score =  596 bits (1537), Expect = e-174
 Identities = 396/1116 (35%), Positives = 586/1116 (52%), Gaps = 130/1116 (11%)

Query: 42   KIDTDLYSRQLGTYGFDLMNKLVKLNILIINVKGVGLECAKNLILSGPQSVCIYDNDICD 101
            +ID  LYSRQL   G + M K+   N+LI+ +KG+G+E AKN++L+G +S+ ++D +   
Sbjct: 13   EIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQ 72

Query: 102  ISDIGVNFYINEKDVEDKSCRSDAVLKELQELNNYVHIYNYKGTIEKNWLENFDVVICCD 161
            ++D+   F++ EKD+  K  R D    +L ELN YV +       +   L  F VV+  D
Sbjct: 73   LADLSTQFFLTEKDIGQK--RGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATD 130

Query: 162  -INKEDLIKYNNMIRGIDKKRIAFLSCNIYGLCGYIFVDFNKEFICYDSNGEQVKSCNVS 220
             ++ ED +K N          I F+S    GL G  FVD   EF   D  GE+ ++  VS
Sbjct: 131  TVSLEDKVKINEFCHS---SGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVS 187

Query: 221  KISKELEGKVSFDFDKTSPFEEGDYVQFSNVEGMTEXXXXXXXXXXXXXX-TFEIGDTSL 279
             I  E +G V+   D     E+G++V+FS VEG+ +                F IG    
Sbjct: 188  DI--EPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKE 245

Query: 280  YSEYIKGGICTQVKKHLKLNFYPYEYICVXXXXXXXXXXXXXXXXQNDNHFLDTCNNIIY 339
            Y EY KGGI T+VK   K++F                                     + 
Sbjct: 246  YGEYKKGGIFTEVKVPRKISF-----------------------------------KSLK 270

Query: 340  ENIPQPNSFIISDYAKFDMSNHLHYSIQALKWYELQNEKGLPEN-SDEDALEKIYNYAVT 398
            + +  P  F+ SD+AKFD +  LH   QAL  + +++   LP   +DEDA E I    VT
Sbjct: 271  QQLSNPE-FVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIK--LVT 327

Query: 399  LNNKDKEEKKSYAVEQLKKDVVYNVCRYSKSHIAPVASFFGGLLAQEVIKF-TGKYMPIY 457
              +  + E     V+ + +D++  +   ++  I  V +FFGGL+AQEV+K  +GK+ P+ 
Sbjct: 328  DLSVQQPEVLGEGVD-VNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLK 386

Query: 458  QLLYLDFFECISLNEKVDINE--IKKMNCKNDNIITVFGKSFQKKLNNLNVFLVGSGALG 515
            Q +Y D  E +   +    NE   + +N + DN I VFG  FQKK+ N  VFLVGSGA+G
Sbjct: 387  QFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIG 446

Query: 516  CEYAKLFSLLDMCTRXXXXXXXXXXXXXXXXLACCGKLTITDNDNIEVSNLNRQFLFRRE 575
            CE  K ++LL + +                     G + +TDND+IE SNLNRQFLFR +
Sbjct: 447  CEMLKNWALLGLGSGSD------------------GYIVVTDNDSIEKSNLNRQFLFRPK 488

Query: 576  HVGKSKSLVSSEIIKKKNNNMH--VQSLETKVGAENEHIFNEEFWTKQNIIVNALDNIQA 633
             VGK+KS V++E +   N ++   + +   KVG E E IFN+ FW   + + NALDN+ A
Sbjct: 489  DVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDA 548

Query: 634  RQYVDNKCVWYSKPLFESGTLGTKGNVQVIIPYLTQSYNDSYDPPEDSIPLCTLKHFPYD 693
            R YVD +CV+Y KPL ESGTLGTKGN QVIIP LT+SY+ S DPPE SIPLCTL+ FP  
Sbjct: 549  RTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNK 608

Query: 694  IVHTIEYARDIFQGLFYNTPLSIKQFLNDKEEYINKIQEEGNNASLLENLQNVINSLKEI 753
            I HTI +A+ +FQG F ++  ++  +L         +++ G+   +LE++ + ++S    
Sbjct: 609  IDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKQSGDVKGVLESISDSLSSKPH- 667

Query: 754  SSQCNFDFCIKKSVELFHNNFINQINQLLYSFPLDYKLSSGEYFWVGQKKPPQPIVFDVN 813
                NF+ CIK +   F   F + I QLL++FP D K S+GE FW G K+ P P+ FD+ 
Sbjct: 668  ----NFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIY 723

Query: 814  NEMIQEFLLSTSNLLAQVYNI--------PPCFDINYIINVAKKIEVKPFEPKKVKINMD 865
            N     F+++ ++L A  Y I        P   +   +I+     E  P    K+++N D
Sbjct: 724  NNDHFHFVVAGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDD 783

Query: 866  EKNLNNISISFAEEEKIIDDFCKELL-XXXXXXXXXXXXEFDKDEQTNLHVNFIYAFSNL 924
            + + N  + + ++E   ID     L              +F+KD+ TN H+ FI A SN 
Sbjct: 784  DPDPNANAANGSDE---IDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNC 840

Query: 925  RAINYKINTCDKLKAKIVAGKIIPALATTTSIITGLVGIELLKYVNYYDNIQAYVKLSDE 984
            RA NY I T D+ K K +AG+IIPA+ATTTS++TGLV +EL K ++   +I+ Y      
Sbjct: 841  RAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQY------ 894

Query: 985  QRKKEKHDVLSYFKNAFINSALPLFLFSEPM--PPLRMMDKEYDELMKGPVKAIPNGFSS 1042
                         KN F+N ALP F FSEP+  P     +K+YD++              
Sbjct: 895  -------------KNGFVNLALPFFGFSEPIASPKGEYNNKKYDKI-------------- 927

Query: 1043 WDKIVISIKNGTIK--DLIDHINEKYSIDVNLISVGNACLYNCYLPAHN-KERLNKPIHE 1099
            WD+  I    G IK  DLI+H  +   +++ ++S G + LY  + P    KERLN PI +
Sbjct: 928  WDRFDI---KGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQ 984

Query: 1100 LYKQISKQDLLEDKNYIIVEASCSDQDLVDVLIPSI 1135
            L K ++K+D+    + +I+E    D++  DV +P I
Sbjct: 985  LVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFI 1020

Lambda     K      H
   0.319    0.137    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 2697
Number of extensions: 151
Number of successful extensions: 20
Number of sequences better than 10.0: 1
Number of HSP's gapped: 5
Number of HSP's successfully gapped: 5
Length of query: 1140
Length of database: 1024
Length adjustment: 46
Effective length of query: 1094
Effective length of database: 978
Effective search space:  1069932
Effective search space used:  1069932
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 32 (17.6 bits)
S2: 32 (16.9 bits)