>YCR057C PWP2 SGDID:S000000653, Chr III from 223224-220453, reverse
           complement, Verified ORF, "Conserved 90S pre-ribosomal
           component essential for proper endonucleolytic cleavage
           of the 35 S rRNA precursor at A0, A1, and A2 sites;
           contains eight WD-repeats; PWP2 deletion leads to
           defects in cell cycle and bud morphogenesis"
          Length = 923

 Score = 36.2 bits (82), Expect = 5e-06
 Identities = 19/93 (20%), Positives = 46/93 (49%), Gaps = 3/93 (3%)

Query: 70  YTKYVRAHLNVIKLTTNERIIFGGDKIG-NVYIWSAISGFLINTFQAHFGPIKDILIDQL 128
           +T   R   N + +  +  ++  G     ++++WS  +G L++    H GP+  +   Q 
Sbjct: 425 FTGTERIQFNCLAVDPSGEVVCAGSLDNFDIHVWSVQTGQLLDALSGHEGPVSCLSFSQE 484

Query: 129 VNVLYTYSDDNIVHVYNLHDLFRKKKIQPMLFY 161
            +VL + S D  + ++++    R ++++P+  Y
Sbjct: 485 NSVLASASWDKTIRIWSIFG--RSQQVEPIEVY 515

 Score = 31.6 bits (70), Expect = 1e-04
 Identities = 13/50 (26%), Positives = 25/50 (50%)

Query: 97  GNVYIWSAISGFLINTFQAHFGPIKDILIDQLVNVLYTYSDDNIVHVYNL 146
           G + +W   SGF + TF+ H   +  +   +   V+++ S D  V  ++L
Sbjct: 367 GKIKVWDITSGFCLATFEEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDL 416

 Score = 26.6 bits (57), Expect = 0.004
 Identities = 15/62 (24%), Positives = 28/62 (45%)

Query: 85  TNERIIFGGDKIGNVYIWSAISGFLINTFQAHFGPIKDILIDQLVNVLYTYSDDNIVHVY 144
           T E + FG  K+G + ++   S   I   Q HF     +      + + T S+D  + V+
Sbjct: 313 TGEWLAFGSSKLGQLLVYEWQSESYILKQQGHFDSTNSLAYSPDGSRVVTASEDGKIKVW 372

Query: 145 NL 146
           ++
Sbjct: 373 DI 374

 Score = 24.6 bits (52), Expect = 0.016
 Identities = 9/35 (25%), Positives = 21/35 (60%), Gaps = 1/35 (2%)

Query: 385 TTFIGHKSQVLKCYVDDKKQILISLASDG-IKIWD 418
           TTF GH+  V+  +    ++ + +++ DG + +W+
Sbjct: 185 TTFNGHRDYVMGAFFSHDQEKIYTVSKDGAVFVWE 219

 Score = 23.5 bits (49), Expect = 0.035
 Identities = 13/50 (26%), Positives = 22/50 (44%), Gaps = 1/50 (2%)

Query: 386 TFIGHKSQVLKCYVDDKKQILISLASDG-IKIWDIYNCYAIKTLKYGENV 434
           TF  H S V       + Q++ S + DG ++ WD+      +T    E +
Sbjct: 382 TFEEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDLIRYRNFRTFTGTERI 431

 Score = 22.3 bits (46), Expect = 0.078
 Identities = 8/32 (25%), Positives = 17/32 (53%)

Query: 398 YVDDKKQILISLASDGIKIWDIYNCYAIKTLK 429
           Y  D  +++ +     IK+WDI + + + T +
Sbjct: 353 YSPDGSRVVTASEDGKIKVWDITSGFCLATFE 384

 Score = 21.9 bits (45), Expect = 0.10
 Identities = 10/35 (28%), Positives = 18/35 (51%)

Query: 379 LNLKDFTTFIGHKSQVLKCYVDDKKQILISLASDG 413
           +N K FT    H+  +    ++ +  +LIS+  DG
Sbjct: 43  INNKSFTFEYEHRKNIAAIDLNKQGTLLISIDEDG 77

 Score = 20.8 bits (42), Expect = 0.23
 Identities = 8/30 (26%), Positives = 15/30 (50%)

Query: 186 LISLTNDGTIYVWGLKSKEAVHILKTQTEC 215
           LIS+  DG   +   K++  +H    + +C
Sbjct: 70  LISIDEDGRAILVNFKARNVLHHFNFKEKC 99

 Score = 20.4 bits (41), Expect = 0.30
 Identities = 16/62 (25%), Positives = 21/62 (33%), Gaps = 3/62 (4%)

Query: 86  NERIIFGGDKIGNVYIWSAIS---GFLINTFQAHFGPIKDILIDQLVNVLYTYSDDNIVH 142
           + R I    K  +  IWS  S        TF  H   +           +YT S D  V 
Sbjct: 157 DSRFILTTSKDLSAKIWSVDSEEKNLAATTFNGHRDYVMGAFFSHDQEKIYTVSKDGAVF 216

Query: 143 VY 144
           V+
Sbjct: 217 VW 218

 Score = 19.6 bits (39), Expect = 0.50
 Identities = 16/83 (19%), Positives = 29/83 (34%), Gaps = 9/83 (10%)

Query: 116 HFGPIKDILIDQLVNVLYTYSDDNIVHVYNLHDLFRKKKIQPMLFYQHXXXXXXXXXXXX 175
           HF  I  +   Q    + T S D    ++++     +K +    F  H            
Sbjct: 145 HFQDITSLTWSQDSRFILTTSKDLSAKIWSVDS--EEKNLAATTFNGHRDYVMGAFFSHD 202

Query: 176 TPNIYDTLYTLISLTNDGTIYVW 198
              IY       +++ DG ++VW
Sbjct: 203 QEKIY-------TVSKDGAVFVW 218

 Score = 19.6 bits (39), Expect = 0.50
 Identities = 8/34 (23%), Positives = 16/34 (47%)

Query: 186 LISLTNDGTIYVWGLKSKEAVHILKTQTECCTYI 219
           +++ + DG I VW + S   +   +  T   T +
Sbjct: 360 VVTASEDGKIKVWDITSGFCLATFEEHTSSVTAV 393

 Score = 17.7 bits (34), Expect = 1.9
 Identities = 5/23 (21%), Positives = 11/23 (47%)

Query: 196 YVWGLKSKEAVHILKTQTECCTY 218
           Y W +  K   +  + + +C T+
Sbjct: 246 YSWRITKKHFFYANQAKVKCVTF 268

 Score = 17.7 bits (34), Expect = 1.9
 Identities = 11/31 (35%), Positives = 17/31 (54%), Gaps = 3/31 (9%)

Query: 11  DNHDVLLVNLDNERCESKFENSI---KDDEK 38
           D+ +VLL +  +E  E   EN +    DDE+
Sbjct: 862 DDDEVLLKDDADEDNEENEENDVVMESDDEE 892

 Score = 16.5 bits (31), Expect = 4.3
 Identities = 10/39 (25%), Positives = 19/39 (48%), Gaps = 2/39 (5%)

Query: 32 SIKDDEKKIC--MLNNGNFLILNANKKMIYQYIYNKSTA 68
          +  DD K++   + N  +   L  NK   ++Y + K+ A
Sbjct: 21 TFSDDGKQLLSPVGNRVSVFDLINNKSFTFEYEHRKNIA 59

Lambda     K      H
   0.322    0.138    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 998
Number of extensions: 59
Number of successful extensions: 15
Number of sequences better than 10.0: 1
Number of HSP's gapped: 15
Number of HSP's successfully gapped: 15
Length of query: 502
Length of database: 923
Length adjustment: 39
Effective length of query: 463
Effective length of database: 884
Effective search space:   409292
Effective search space used:   409292
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)