>YLR196W PWP1 SGDID:S000004186, Chr XII from 543970-545700, Verified
           ORF, "Protein with WD-40 repeats involved in rRNA
           processing; associates with trans-acting ribosome
           biogenesis factors; similar to beta-transducin
           superfamily"
          Length = 576

 Score = 78.2 bits (191), Expect = 7e-19
 Identities = 91/407 (22%), Positives = 166/407 (40%), Gaps = 69/407 (16%)

Query: 126 EDELNIEENDSIVINGKIYSDMGTLEIHVFN-----------------YDEDIFN----- 163
           + EL +  +D++V+  +   D+  L+I+V++                  D D+       
Sbjct: 135 KQELQVYPSDNLVLAARTEDDVSYLDIYVYDDGAGFHSSDIPVEEGDEADPDVARGLVRD 194

Query: 164 ----IYDDVIIDNYPLCIE----TIHQSYFKEKNIVAVGTLDCSIQLWDLYNIDMLEPLY 215
               ++ D+++  +PLC+E     +  +  +  N  A+GT D  I++W+L  +D   P  
Sbjct: 195 PALYVHHDLMLPAFPLCVEWLDYKVGSNSEEAANYAAIGTFDPQIEIWNLDCVDKAFPDM 254

Query: 216 YLG---DNEMXXXXXXXXXXXXXXXXIHYEKKNIKNIPEDEEPNNISKQKIKGHTDCITS 272
            LG   DN M                +  +KK  K+     +  +I+      HTD + S
Sbjct: 255 ILGEPLDNSMVS--------------LKSKKKKKKS-----KTGHITTH----HTDAVLS 291

Query: 273 LNSSKILPSLLVSGSKDSTVKLWDLNNLNNLHTF-SFH-QKKINNLSFHSKDKNLLFSTS 330
           +  +K   S+L S S D TVKLWDLN+ N   +  S H  K +++  +H  + ++L +  
Sbjct: 292 MAHNKYFRSVLASTSADHTVKLWDLNSGNAARSLASIHSNKNVSSSEWHMLNGSILLTGG 351

Query: 331 SDKTLKIYDIR---QNQVALDIHLSNIPEATIWNTHEENIILSSYIDGYINKIDIKYINT 387
            D  + + D+R   ++Q++         E        ENIIL     G +   DI+  N 
Sbjct: 352 YDSRVALTDVRISDESQMSKYWSAMAGEEIETVTFASENIILCGTDSGNVYSFDIR--NN 409

Query: 388 SSNKPQNNYLVNFKAFENSCTSLLSMNYKNLTLAGSEDGVIKAYDFHNLLNEQ-PHCVYS 446
            + KP      +       C++       +    G +   +  +   +  N + P  V S
Sbjct: 410 ENRKPVWTLKAHDAGISTLCSNKFIPGMMSTGAMGEKTVKLWKFPLDDATNTKGPSMVLS 469

Query: 447 KNLK----KNLFYMKDNEDWPNVVFLGCDKLYD-WDVFECEEIKKYF 488
           ++          +  D E    +V  G +K+   WDVF    ++K F
Sbjct: 470 RDFDVGNVLTSSFAPDIEVAGTMVIGGVNKVLKLWDVFTNRSVRKSF 516

 Score = 17.7 bits (34), Expect = 1.2
 Identities = 11/46 (23%), Positives = 20/46 (43%), Gaps = 1/46 (2%)

Query: 310 QKKINNLSFHSKDKNLLFSTSSDKTLKIYDIRQNQVALDIHLSNIP 355
           Q++   L  +  D NL+ +  ++  +   DI         H S+IP
Sbjct: 132 QEEKQELQVYPSD-NLVLAARTEDDVSYLDIYVYDDGAGFHSSDIP 176

 Score = 15.4 bits (28), Expect = 5.7
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 121 KKYIYEDE 128
           +KY+ +DE
Sbjct: 18  EKYVLDDE 25

 Score = 15.4 bits (28), Expect = 5.7
 Identities = 17/96 (17%), Positives = 43/96 (44%), Gaps = 3/96 (3%)

Query: 247 KNIPEDEEPNNISKQKIKGHTDCITSLNSSKILPSLLVSGSKDSTVKLWDLNNLNN-LHT 305
           K + +DEE   I++       D   +L  ++    +    +  S+ KL D  ++++ L  
Sbjct: 19  KYVLDDEEVERINQLAQLNLDDAKATLEEAEGESGVEDDAATGSSNKLKDQLDIDDDLKE 78

Query: 306 FSFHQKKINNLSFHS--KDKNLLFSTSSDKTLKIYD 339
           ++  +     ++ +   KD ++    S+D  +K ++
Sbjct: 79  YNLEEYDDEEIADNEGGKDVSMFPGLSNDSDVKFHE 114

Lambda     K      H
   0.315    0.135    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 719
Number of extensions: 52
Number of successful extensions: 15
Number of sequences better than 10.0: 1
Number of HSP's gapped: 7
Number of HSP's successfully gapped: 7
Length of query: 490
Length of database: 576
Length adjustment: 35
Effective length of query: 455
Effective length of database: 541
Effective search space:   246155
Effective search space used:   246155
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 26 (14.7 bits)
S2: 26 (14.6 bits)