Protein MAL13P1.148 (PlasmoDB link) - New domain WD40 (Pfam link)

Sequence and domain localizations (colored) at: 1751...1793 / 1973...2010 / 2017...2060 / 2118...2156 

   1 MEGANKCVIGTKIFIRDKNKVWASAEIINEDEDNIIVKTEDDDIIKLKETDEFYLRNLDL   60
  61 FDSSGLSAPSDLTKLTHLHEASILHSLNLRFDIDEIYTFTGPILIAVNPFKIIKDLYSDN  120
 121 MLAKHVQPIKSKSPHIFATSNSAYLGMCNNNKSQTILISGESGAGKTESTKYVMKFLACA  180
 181 GSDIKKRSLIESQVLESNPLLEAFGNARTLRNNNSSRFGKYIELQFSVDHKNYIKGKLCG  240
 241 AKILTYLLEKVRVCDQQEGERNYHIFYQLCKAVKEANIVDNSIMSNNENDDVENYVNYKC  300
 301 DEDKNKDHIENNICEEPTQKKKKWYHFPSTSKFRNLENVEPMKIDFTDFKEHVHFRYLTK  360
 361 SSVYELNEVNELEEFESTVHAMQTIGISNTEQYQIFKILEGILYIGNILFNNDETKEEAT  420
 421 ILEVSNDDLRKAAYFLDIDENDLINSLCYKTIVANNEHYKKPVNSNVANDIRDALSRAIY  480
 481 GCLFLKVVERTNESIGYIKDINLFCGVLDIFGFESFPVNSFEQLCINYTNECLQQFFNNF  540
 541 IFKCEEKLYMEEGIRWDPLDFPDNKDCIDILESKPYGVFCMLDEECYIPSGRDKSFCSKI  600
 601 ISKHTSSSNNNQSNKRFKSIKTDSSSFIIVHFAGQVVYNSTGFLEKNKDQLSLDAQKLLL  660
 661 HSKNTYVSHLFETYLRRNTDKRKFVTVSSEFKEQLNLLMTRIKETEPHFIRCIKPNAQNV  720
 721 PDVFDRISVNEQLKYGGVLQAIKVSRAGYPVRLSHAECVQDYKILLNKEDRHKLEMYNKD  780
 781 NKSWSYKANFILSSLYVTKEIQEYINNLKLLKDKKKEEENKFFGKLSSKKNKKMQDTTTT  840
 841 MNEVSNNVQINNKDETNNNNNNMKDIVYDPVCGDANEEEEKNNLFIWSVGKNLCFFKSDA  900
 901 YNILSTLRSDLRSLKAIVIQKNYKTYTQKKLYELMKRKIIIIQRWFRNRLNIIRKEKLKR  960
 961 QEAEKLICSYIYTYIIRKRFLHKRNCCILIQSHIRRYLMVRFYKTYRQNYYASKIQATWK 1020
1021 AYKEHLFYKKLLKSTKKIQLKWKSILARKQLRRLKMESKEVGSLLSRNQVLMKELKKEKN 1080
1081 EKIEIESKLLKASAKIDKLIKKIDNLEKDNKNNEKVIKDLLEKVSLLSYKQSNECISPRH 1140
1141 VSKKNENIKQKKNNKELNKDIIMSLKREDTEHVDSMEIMSIQGNNTHDDPNNVRNCYSTD 1200
1201 TNLTNYLNNNKSNNNKDHNNDHNNNNNDDGDGEDIYMDNNLTFTQEKIGDLKIRNTIRNE 1260
1261 KNEEKYNLLNKIKKLEIQNKEYIKQNVTLNDKYNKLVSLLGQIKDTNNNVYNDVLINNIN 1320
1321 NYHSNGMSNKLLLNNYNNYHNNNNNNNNFFKNLTNLSSCNSNSLIEPKIENNINYDNKSS 1380
1381 FKKNDGIVDILVCGPRNVGKTSLLEDLFVRLGDEDNLGLLRKNKKLVNNDLSCYNYYNTY 1440
1441 IITHKCSQIKIVDCGYSSNKNVEESLFNYIKNSICIIVVFDATNKESINPAVHLLQEASL 1500
1501 INVKKTTKLYLFENIFNEKINLNFNKNDVSYAVRVSKACNASYVKALDIYDIVNNYANKI 1560
1561 TLHSNYFLDNTHNNCNYNNNYNYNYNHVTSVPPNQHSEHNNNNYYHNNKEKDNDNDKDKD 1620
1621 IYVKGLAHLNHMNKSKRNTHSYMSSYHEESLKDSDDAALSSFGNKSNDLIKSKRGDIGKN 1680
1681 KYNNNNKNNNSSNNNNNNIYSVVNTLKAICGIQNSNKKNQQIQLLRESMPLNNYIYGNKK 1740
1741 YNSDLGKGLQPVYEITLKGNIPITYLCMGQDNINKNYTLLSVGCKDGVIYIYKCFRTSLE 1800
1801 LKNDYFYYYNDDSSMYNMNNNMDKNVNNVYNNMDKNMNSNTTLNIQNNDNNNNNNNNIVG 1860
1861 CDDNVKKSSSIMSLKNDSNKTYDESSTCTKLLSKLSGHKKAITCLVFSFSEDKIISSSID 1920
1921 RTIKIWEVSTGFLLKVFSDSSATLSVLLFPTNLDIFLCSNCTSLLRIVNLNSGQVYQKIK 1980
1981 VESEIRALEMDDTCLNIFAGSKNGTIYVLEVIYNERVEIKFRFLFSLSPITCIKFIPRHS 2040
2041 VKTSPAIIVNSCDNHIGIIECVYGNKGILTTLYVKHRIRINHALLPIRNCYSRFGGGWVM 2100
2101 SGSEDGNIYICSLLPQSNYKLIFLKHHKAPVMAVVVNNIDTLMVSGDSKGNIVFWRRSFV 2160

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 1751...1793 
   1 geck.vl.gHstVtcvafspd....sgpllasgSrDgtikiWd   43
1751 PVYEiTLkGNIPITYLCMGQDninkNYTLLSVGCKDGVIYIYK 1793
Occurence 1973...2010 
   1 geck.vl.gHstVtcvafspdgpllasgSrDgtikiWd   38
1973 GQVYqKIkVESEIRALEMDDTCLNIFAGSKNGTIYVLE 2010
Occurence 2017...2060 
   1 geck.vl.gHtstVtcvafspd....sgpllasgSrDgtikiWd   44
2017 VEIKfRFlFSLSPITCIKFIPRhsvkTSPAIIVNSCDNHIGIIE 2060
Occurence 2118...2156 
   1 geck.vl.gHtstVtcvafspdgpllasgSrDgtikiWd   39
2118 NYKLiFLkHHKAPVMAVVVNNIDTLMVSGDSKGNIVFWR 2156