Protein MAL13P1.301 (PlasmoDB link) - New domain 7TMR-DISM_7TM (Pfam link)

Sequence and domain localizations (colored) at: 1103...1412 

   1 MKTQTLSLMNINGKRKFLGTNNKIYRKVIINPTSEDDIQKFCRNYFRIYNFSLYNFIRRL   60
  61 ISFDAILVYSLFLTVYIFSEINHGETKKYLFIDTAISLFFNIILLIVIESLFELKKLKDV  120
 121 KNANSQYYLRIVPKMSYFEKVMTKDIKVGNIIRIFQGDEFPADVVILYVKNNANAIVDSF  180
 181 KIDGLFRKSIKYAVDKYKIDKDYLKMLSEINGVIRCELPNKNIFCFQGNFKLDKHPRSLL  240
 241 LNYENFALQSSVLKGAEYIDAVVVYTGADTKKNLNIPQKIEENKTFCIKMNNIVYYLIFM  300
 301 YFVFVVLSIVIKTIFFHKKNSFQNSRDSFLSMLEDFVGLYILVLPIMMYSEKSLIYIIQS  360
 361 LRIENDLRMRNTDSEKPKVFNKNKNDSLGNVDLLATSRNGVLVKRKELLVSCVINNVMYG  420
 421 KKDIICSRTNFKLPTLNILDSERKNVSNLLNLDERIFKDPENIFFPTRDFYSFLKLFENK  480
 481 ISSIYNPYSSSLSNLLKEKYKNYVNEEILNKNVKLTSFVKSQLTIGYNQICEDDELSYNC  540
 541 YEIKEDSQKENIQSVKIEDFILGLCGCNRIIIYNEKSLDISMNEYKSDNFMETYSKFETE  600
 601 NEEYHENDHDEYHNMEHSDDENINSIEYEDICLYNIIRNTGFSIYCYKNTLFLYNLMKEC  660
 661 KVYFLTCYHDFLRSNKFSMCILKCGYSINNEKEGGILYVRGYDFNILPYISKEKNNIKKI  720
 721 KNVIKIYTLNYLKVIILCKKQISNEDIAKYIILKSISKKLSFKFYDLIKLFFLYDLEVIG  780
 781 IIGLKNQLREGVKETFNDVINFDIKSWIFANECSKDTYLTALQCNLIVSSSNLFLINYYN  840
 841 LKNTHEEGANILFHNFISSLYKLKSNSYAVVINDESIKNIMTNVESMKIFLCIAMRATVV  900
 901 LFCKLQNETKGKIIRTLYALTSPKLTVLGIGTTLNDAYLLKYSSISVFLSLNEHVNILYN  960
 961 ISDYVLQEFKFISELLILGRLNRFSLCKVFLWIIYLKITVVSFYFFHNFDNYFSGSSASS 1020
1021 ILYTQTTFALLHYFLIIAFSAYEIDLPYKFVRRLPYIYQLSRRKYFLNNNIILLTIIEAI 1080
1081 LISLTSYYILRLNVFHLITHREFTFHIFILNVFITTEKILLLSKTWHIYFFIMAVLIIGI 1140
1141 LLIYVNIFTLVDCIKNGKCEFSLFQMENIYFWTSLFPILYINFIFDKLMKYIKNRIYPDI 1200
1201 SDYLRKYFLRRICCHNNDKFLSQRKIKGINKFVNFEKNDILLKYIPTPKIYKIKDDPTYY 1260
1261 NKSKRSKFLYDTFRKVIDINVKYRNQQLNLEYKTYEKGNKLKLRIIVILLFLIYIIIFSS 1320
1321 QTIIDINTKSNIHYITMFYIIYFVLACVLLIYIRIRNKATSTFFFFLSRFLLICGFCIEL 1380
1381 YDNISNDILNVLITYSFTVSYIFFMSFKILEALLVCISILLLTFGVYYEKNKNMIDICTH 1440
1441 FCSNPYLSINNLDHMNISCLCKKQIVIFLISLLSFTLICLSMKYYEIFYLKKKFLFRYKQ 1500
1501 KVNLAKQIEILHTMLPNFLVEYLLISDPKNDGIMVGKNISGEDRGIISVIFCDIDDFQNM 1560
1561 VSTLQPHVLVETLDNLYLYFDKCIKYFNCIKIETVFESYLAASGLSEKKNNALDKIMYDT 1620
1621 KCAIKLAIAQLSAKYYISYKVLDTREHFSDNSTSYDKYINKNISLKIGIHTGKAISGVIG 1680
1681 SVKPQYALFGDTVNTASRMKSTSLPDHIHVSYDTYKYLKEDNTFIWKERKVFIKGKGKMK 1740
1741 TYLLVDILDDVKRKGESLNYYSSSNLLLSQLGSEAVSIYEEREDIKEGSMDIIKESSRDI 1800
1801 IKEDSRDIIKEISTNISKSSSRNISKSSSRSISDIKEGQIIDKEDLIFKINRMKNKIDSR 1860
1861 YSKRIDKESRDKISDKTNHVLDEVVKHSDIHLLNYEINNKRCKKMKGDTNNENKLIGDIF 1920
1921 NMYDKKIKYIYKKNYKSKSMENISFIKHYRNTKYKKSDYLLLDNKGESKKFKRNTSYVLE 1980
1981 SPLHLIGDIVDNNIKRKKKKKEIKTIVSDDMFTSPVNIKEYNYNEQERKKEIVGNLSYDK 2040
2041 TKKIFPFIKFTKEGRIKKKKIEKKEKKEKKENNNNFLYNDDYSSYSSPKYGDNENNFVIK 2100
2101 YIRERKDFQKKFDHPNFNFSKFLHNYNPMKNKNKNKKNNKNVRRNEYPNYTSSSKDGVSY 2160
2161 NFLSDSLFSSDNEYSSDNEYSSDSEKYYKKRFKKNKKIIKFDDLFTKIYIKKKRLLQMNN 2220
2221 YDVKGKGKKLKNKGMERNKTKYKNVNEITKMKYFVNNENRDHEVNKEDISKSMQKYFLHI 2280
2281 SKHKKEQIEDKKKTHKYFHKNVECVYPYAGNNINHNFSRNEKRKYSINLYDHLDEQEKIK 2340
2341 GKKKYFNKDKELIGSINKQTERKPKKKNKKNIENKKDKKKIRMITNKTKEKHSNSIISVE 2400
2401 EQNMNHNNSLKKKEVNFTGKNEEYLNRANTNCSLGIKEMEEDVYEFHSNNIYYNNQTSYS 2460
2461 DDINNTTKLKGMGNNTNDISKNKGKNKLGKKISFFSMNNKYHESEIMNEEDNKNMLNLTQ 2520
2521 SQIINKDKYNYFTHCPSLKKKKSVFTKINNLFKNYFKSIDVHEKFGFSKKFKFHSKDSDD 2580
2581 IKGNNNKISKNRYNNNNNNNNSNYSNIDSGKYSHNNKKNHHHNNNKYHHHNNNKYHHHNN 2640
2641 NKYHHQNNNYEKHHHSNNSRVMLSKGEKTEKNENVDYAYQFDNYDKKLLKKLTSNLQLNK 2700
2701 KNVKNFNMFYYKFNDEELEEEYTRNYYREIINIDLTKKLIIIFIFTEIFLSLCNIIELSF 2760
2761 YEKKLRYNDSIVIIWLIRSIYLFIITYIWIILKTKLKEYKNNSSKMMWTIFILNIFLCSW 2820
2821 GIILIDLSCIHYSMLLGNKNERALFFMKDASELIICIQLIFIKNMLFKHKFFFFVFFYIF 2880
2881 LIYSFSKLFSIHTCQTHICCSIILFISINILYFWYSEYLDRIQFLVKRKRNRMEKISQDF 2940
2941 LTKILPRQVLEEYQNDNLQLTYKHEKIAFLFADIVGFTKWSKTVSPKEVLKLLQKLISKI 3000
3001 DKDTIKLGLYKLFTIGDAYVATSQPNSSITDESEALEGILNILKLAKLILHNINTIKIQF 3060
3061 NKHDFNMRIGLHYGSCVGGIIGSVRIRYDMWGLDVLIANKIESNGIPGEIICSEQFRHFF 3120
3121 IQNEPQA 3127

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 1103...1412 
   1 ralifglllGillllgfYnLf....lylsrrsyLyyalyillfyqlslsglafD.wpnip   59
1103 FTFHIFILNVFITTEKILLLSktwhIYFFIMAVLIIGILLIYVNIFTLVDCIKNgKCEFS 1162

  61 ffaqklaylllvllalffllFlrsflylksssrrl....drllgilalllf.........  119
1163 LFQMENIYFWTSLFPILYINFIFDKLMKYIKNRIYpdisDYLRKYFLRRICchnndkfls 1222

 121 ............................................................  179
1223 qrkikginkfvnfekndillkyiptpkiykikddptyynkskrskflydtfrkvidinvk 1282

 181 ................................laillalfltdylv...anriaqvlvll  239
1283 yrnqqlnleyktyekgnklklriivillfliyIIIFSSQTIIDINTksnIHYITMFYIIY 1342

 241 filillllgikawrkgyrdArlfliaflvflvgglvgllglipnniltsyalllglvlev  299
1343 FVLACVLLIYIRIRNKATSTFFFFLSRFLLICGFCIELYDNISNDILNVLITYSFTVSYI 1402

 301 lllslaLadR  310
1403 FFMSFKILEA 1412