Protein PF14_0112 (PlasmoDB link) - New domain Toprim (Pfam link)

Sequence and domain localizations (colored) at: 379...458 

   1 MLLYKFYFLYFLLVHLSLCIRYRNQNKTDSYLKTNYKLLKKRKKYENRRYKFPKNRKGNN   60
  61 NNIYDAINNNNTNNIYNNDTYKNRIFFRNEKNDENFIKTNKYSYYEKRNKIKLNSATSTF  120
 121 VSKYYKININDVYNYLHRKKYEFIETDIKITLKYCPFCPPHKYKYDNMYKHEIFKNTGNS  180
 181 YCHRCGYKGSFYDFKLKMGDLITSNFESTVVHNNNFYEEEEEKITLNDVKVYNMNLLYSK  240
 241 EAENARNYLMNVRKLSIDTLKKFLIGFSVMEFQSFESSGKFEKHECIIFPFIKKVDEINM  300
 301 IETNGINSNMNKMNNNNNNNNNNNNNNNNNNNNINDNYEVVRIKIRSLKDKGYMRLYPKN  360
 361 VRNEMKLFFFGDHLIKNSEEIVLTEGEIDAMTISQETKYPAISLPNGSKSLPIYLLPYLE  420
 421 RFKKIHLWLDFDKAGKSSVFNFVNKIGLGRTNVITDANVHYLNPDVFKRRQKSRLTKKSL  480
 481 LLTSMASNAMEILQKDKEENMHNIYDTTNNDYMDNKILSNNLKSISSDKIKKKEEIDLFN  540
 541 GQKISSNNINVNILKNKKNETDNITNKENKSDNNLKEGMEKKEIQNEISVIEDNNNNKNN  600
 601 IIENNNDDMSEKIKVEKSIEDNISYFVDNNIMYIPNNIIIKDANDCLKHNIDIRFFIETS  660
 661 EKVKHSQILNFNDLRQRILEELKYPDRINGVKSKTIPSLNKYLYGLRMGELSIWTGSTGV  720
 721 GKTTLLSQLSLDYCIQGVSTLWGSFEINNVKLGKVMLNQFCGKNLEKNIELFDIYADKFE  780
 781 LLPLKFLKFHGSTNIDQVIDAMDYAVYAYDVKHIIIDNLQFMLNINKFSDIYELQNIAID  840
 841 KFRSFSTNKNVHITLVVHPRKEDNNLLSISSVFGSVKSTQEADNVFIIQRHVSKTNETVF  900
 901 FIDIKKNRFKGSLGKIPYLYNKENMTIKEISINNFNEHVVSNTYLPSNKFSSSSLQNNTT  960
 961 NNNFIQNDNLNFTLCDEYDYMKQLADEYESKHAFKKGYRSKLDPNLRVNNIDMIKTEIID 1020
1021 NSDMNNNKNVTLYVDSLENIKTISTDDKTNDDKRDVNEIKSIKNNERKNTLKIDGNKSLG 1080
1081 STQNLNYENENKNNNNNNNNNKSNQEMEKNNIDDKSSTGNNKNINGNSKGNNNINNNNKN 1140
1141 KNSSSSSSSSSNYNNNEGIKNILNTSAQNNIPFKDTIWSYTLTNEGLIKLCEELKDEEAE 1200
1201 KLKNRVVVLSMRNCIIDNNSSIKDIRTFIKTNKLNIKTAGKNLKKMDIFISILQNIPKEY 1260
1261 ITIKSGQKYGPNKGLPNDKSKNKIKEPHNNNMLEYNKVGSNIGDGQNTSSSCMNINKIYS 1320
1321 EEENNIYINNNNNNMNKEPQTLLPNDRNDSNSHSYNNINYTMVKNGNEGNINDYLNRNYE 1380
1381 NNVDNHHNDEITKKYIKDNIINVDDNIIKKKDIFKLKNENNEITECAFEYFESKKKFDDD 1440
1441 IESRFFIINDNNYNENINLIYKDIKYCGLDIETTGLEVFDENIRLIQIAVENYPVIIYDM 1500
1501 FNINKKDILDGLRKVLENKNIIKIIQNGKFDAKFLLHNNFKIENIFDTYIASKLLDKNKN 1560
1561 MYGFKLNNIVEKYLNVILDKQQQNSVWNNSLLNNNQLFYAARDSSCLLKLYKKLKEEIKK 1620
1621 ENLHIVNDIENKCILPICDMELNGIKVDLENLQKSTNEILNELNIEKDNLKKKLKDENIN 1680
1681 VNSQQQVLKALQKNNVRDISNKLIENTSDSNLKNFLNHEEIISLRNYRRLYKLYSAFYLK 1740
1741 LPLHINTKTNKIHTTFNQLKTFSGRFSSEKPNLQQIPRQKNIREIFIPNDNNIFIIADFK 1800
1801 QIELKIAAEITNDEIMLKAYNNNIDLHTLTASIITKKNIPDINKEDRHIAKAINFGLIYG 1860
1861 MNYVNLKNYANTYYGLNMSLDQCLYFYNSFFEHYKGIYKWHNQVKQKRALQYSTLSNRKV 1920
1921 IFPYFSFTKALNYPVQGTCADILKLALVDLYDNLKDINGKIILCVHDEIIIEVNKKFQEE 1980
1981 ALKILVQSMENSASYFLKKVKCEVSVKIAENWGSKD 2016

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 379...458 
  1 kvliiVEgpsdakalakalggnvvaslGhlw.piilkkeqlkllkkvilatDpDreGeai  59
379 EEIVLTEGEIDAMTISQETKYPAISLPNGSKsLPIYLLPYLERFKKIHLWLDFDKAGKSS 438

 61 awkllellkygpkvrriflp  80
439 VFNFVNKIGLGRTNVITDAN 458