Protein PFE0270c (PlasmoDB link) - New domain MutS_II (Pfam link)

Sequence and domain localizations (colored) at: 586...725 

   1 MASSNKKQSSILSFFKSNEEKTNKSSCLNEINNKVGDGKGHKQNEINNNVPEKRKSGDDK   60
  61 SGVDSKNKNEKENLGSNKKINMLDMFLSKGEMYNKPKIIDNINKEPINGDMLSTDKNMNV  120
 121 NKTNKMHNLFLDEEKTDMSKTKCSNDDVYDNNVYNNNVYDNNVHNNNVHNNNVRNNNVHN  180
 181 NNIHNNNNYGNIYRNDNCVVKSNECNNNGVELDEDSNYQNMVHNQMLEGRNYMDNLESST  240
 241 EDDIIIKKKRKIILDSVSDKECSDAKENNINKNNCSVDNKLTNLLYEPNKEIDDNLLLLD  300
 301 DNNNNNIKKCIEKRKGDDSKKSQELDGLRNKYLNLPISITNDKFRLYIEHYFLYCNTFEF  360
 361 PKWIQPQYIRDINLRTPDHADYDSSTIWTPPPDHKWAIEYKQAHYTPGMQQFWKIKSRNF  420
 421 DKIIFFKMGRFYEIFYIDACLMHTICSLNWMSGEHKPHLGFPEQSLHFYAKKVINSGHKV  480
 481 VVIEQMETPKELEQRNKESIGPKDKAIKREINEIYTKGTILHDNMLSAETKYLVCFYFDE  540
 541 IENMTNVNNNIKDNDDDHNNIKDNDDDHNNIKDNNDDHNNIKDNNNYTFSQYDNKNKCNF  600
 601 GFVVSDIATSYIAVGYCNDDESRIVLRTILAQLCPAEILYSSKNINKEVLSIFKNIPTSP  660
 661 ELTCLNSFPNIISSFDEINKYFENMPSNLEIYKEQTSVICAFGGFIVYLRSLLLDKKIFR  720
 721 FCKIEKYDLFKRETYMVLDATALKHLEILETQSGDTKNSLYDYVNKTCTNFGARNLRRWI  780
 781 CSPLLDCEKIRERLDVVDFLKNNEQILSLIRMKLKKLPDIERLLNKICIQASQSERGAVF  840
 841 FDNVVNTKLKEFVTFLNAFKEIDTMLIDVNRIERDGELPSRLFQICNTPDICKDNIKGSY  900
 901 PNIGLITNEFLEKIYFDGDKEYKPAEGCDEDIDKINEKEKNVENKLNNVLEHMRTQLKIP  960
 961 TLKFVHAKFKYEVECPDNIPKSFLKNVEITSAKKGYVRIHNDEIKSLVEKLEDIEQEKKD 1020
1021 AIYPFFQKLFHLFYAHYEKYVSACRLVAELDCLQSFAYVVLNTAFPLTRPILHPMDSKQG 1080
1081 EEKTPFLILEDNIHPVVAMLMPNFISNNIYMGCDKEKQSTLLLTGPNMGGKSTLLRQTAI 1140
1141 SVILAQIGAFVPCTYCELTVVDKIFTRLGSSDNLFEGKSTFLVELEDISNLLKQSTKYSL 1200
1201 AILDELGRGTSSFDGTAIALSTLEQISDVIKCRCIFSTHYHLLVEEVKHNKNISNYHMSL 1260
1261 SIDDEQEKIIFLYKFIKGVCPKSFGIHIAKLAGLPKEIIDLAHEKSLLFENVTDEFCKII 1320
1321 KYKNITRSLLNEEADEKLVTLFHKYKKEFA 1350

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 586...725 
  1 NylaAiskgdgnr.yGlaflDlstGefgvsefeDddafeeLlaeLsrlsPkElLlpesls  59
586 NYTFSQYDNKNKCnFGFVVSDIATSYIAVGYCNDDESRIVLRTILAQLCPAEILYSSKNI 645

 61 eseveesqkllelrdrvgrrptweelesaeedlledf.....gvedldgfGlalcAagaL 119
646 NKEVLSIFKNIPTSPELTCLNSFPNIISSFDEINKYFenmpsNLEIYKEQTSVICAFGGF 705

121 lsYlketqkr.Dsrnlphlq 140
706 IVYLRSLLLDkKIFRFCKIE 725