Protein PVX_003750 (PlasmoDB link) - New domain SKI (Pfam link)

Sequence and domain localizations (colored) at: 1668...1792 

   1 MSLLCHPDAVHLLVEDDLGSFLSSLEKERRPTSQIVILTDQATLLNERPTILATLKFFLR   60
  61 HPRDHSKGSLSPEGGRCTLQGKLQKGKHVDETKWSHPLVFPSSDDGDHLGEKYTHSSSER  120
 121 SANQDGKKGRSRNQTEGKAAHQMVLCEAKQGTTHLPGGTDPEELQQLFEKFEQSLGGKAI  180
 181 FTPHLFSQQIKNVLVIISNVKKWDDKVEVAQQLNELFGRDTNLREAQVICFARLKVHLFP  240
 241 ASGRALVAALGGAAVKADRYDEAVHADEDDPPCSNTVTLIRGGLLTSLREGDCKGIFAQV  300
 301 LKLAILNDPKLFTNIKSSNLTQFKKRIKCFLHKLLKNSCDISRRGRRNKKIMNMFRFGTT  360
 361 IGNAIKSARGNPLNGVFTNEQMFLCYGIYYELRILYEVHAVDLISLIDVKEIMMKYKTKY  420
 421 KLSKNYLDYHTHEIMHHLRKAHPSERDKICLVHLTGIGEVHPDVVISIPLSVVCRVLCPM  480
 481 VCFPPRSMHFSRKGTEPTHTWESFVHIEHVGNKSEAIRMIYVSCMSRENTSIGNVTACLD  540
 541 VVVFVKILKEINFDIRLTRQGVATHPEDLSPGGNVLHIRGNIQRSAFLFKRFTYRRGITL  600
 601 NVYNCGTVCRFILPLLCLYICKQNLKAKRRKKRVLKWVLLKGSKQMETTRIIGPLVQVLR  660
 661 QTFKCVNIEYTKKENYLPICISVKEGANLEGRLFCTEYVRIDNYHSSQFVSAMLLLSAFS  720
 721 ETDTRLALSFKRVGRGGTASRRDGRGGTPRGRAAQRRIDPRPNGCVSCCVGTLSSKPLHH  780
 781 TANFSLPAKPNETASHPTQRVERTTHQFSTTSKSFIDLTIRVMKLWGVQVRMKNFCYVLK  840
 841 KGGRYPSYGRGRSKVALRKSVVTRVKRFICVLRGVPPTGGKKGGITKRGREEGEALNSPV  900
 901 RLPVDVNGEEEDLELSRLINPPICAANSAPSCEVQNDLGLLIYFIIGCLIRGENCAIDVG  960
 961 LRLDGVDLYPVGGAGGSRQSGQGEESEPIPRGSHDPRYAHHLSSPRLRRIKAVRRQANIP 1020
1021 NYALLNVLLLLGVDIYVEEGGSPRRSKKVYLLTSKRMSIRQEFLRRLLPLGVASKGGEKN 1080
1081 PVGAVKRAKWEVFQNVHLKVMPLSSRMLLNVVVDVESFSDDFFSLSVLFCYYLLVHPTEC 1140
1141 FSFRIKNVRNQNVKESVRVYNAVIILKLFFQNVLFISCDRNSVYIDRMTHPVENCLFYRM 1200
1201 SKKGELPPGEAPSEAASPTGALLGNNSKYVTNDRGEVYLYVDTQRDHRIIFMVAILSLLG 1260
1261 GNVLIDNNGEVEKSFPHFFDYAHGHLGLNVRYATCGGLSFCSFAKLCGYSLMSGGGGSPS 1320
1321 EEPPSNDRSSPRSNPPHGSTKVENPPRGNQVKCIHNLQQRGANNVAMKMGGAELGKKLHD 1380
1381 SMDHWTTSKGSRGDETKFTHGQAEDPPSSGDDSTDSSSHLEMRHPCEEADGVDAPIGEMT 1440
1441 FAERGRDKCDEDVKGGESKITDSHESRIRGGTTCEGSPISANDQSKWGGRQKRERSMLVP 1500
1501 PRENPPLKDTCGEACDRTPTHGRGALPRDPNYWREYHYEELLHGNDADILHLINQVNRLN 1560
1561 VHIICGIRNVGKSYLSKRVKTSSLVIDLDEFILDGPIRFDRLSIDDFRYYEYVTFVSTLY 1620
1621 LAYLIFAEGNGHQGRGGKPMQGDDIVHQGIAHSMGTTEEAQAVLFENTFLSLQEDVHFNN 1680
1681 KKVNRLYHTMKGRHFLTDFQVPVRSVTIVLGGGIVEFEKSRQVMQKMKNLLLIRRPPREI 1740
1741 YHLCINDRVKPPLRGNLQEIISRRTALFASLNAFHFAIPPEESIKRCLKNANMSRDQLIV 1800
1801 SSFLNFFNYQFFVKPAVKHSYGRAPTTGEGLLSLRLSEFSSFDCASLGGTYEVVELVLDC 1860
1861 PQNGGEPNGEGHKADLLELAIFTIRSYTDKPICVKFPKWVLYPNWWEPPNEGPPGGQKNP 1920
1921 PYRCTPTDLCKYKINLFDVDAHFFKRVGTFMPREREHLFIVISSYRERVHKGRVATDLHK 1980
1981 LDKWHADLIRLTFARATHSDRETLHREITRHYAKRLGNHLISHVRGVRRMPCYDVPPHQV 2040
2041 AHQRSYEISVYTEQNDPLVFLCNDVSHVGCPQQGVAAEEKGRRPHHPESYMHSFYRQGVK 2100
2101 TIISCVPR 2108

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 1668...1792 
   1 TiLAkaLglpFiDqeIEkrtG.msiaeIFeeeellqenaViATGGGavlreenrelLker   59
1668 TFLSLQEDVHFNNKKVNRLYHtMKGRHFLTDFQVPVRSVTIVLGGGIVEFEKSRQVMQKM 1727

  61 GiVvyLdaspevlleLkrdkedkdpeeellelLaeeRkplYeeaadivtdekseevaeei  119
1728 KNLLLIRRPPREIYHLCINDRVKPPLRGNLQEIISRRTALFASLNAFHFAIPPEESIKRC 1787

 121 leale  125
1788 LKNAN 1792