Protein PVX_084445 (PlasmoDB link) - New domain GCC2_GCC3 (Pfam link)

Sequence and domain localizations (colored) at: 871...921 / 926...977 / 982...1032 / 1062...1108 / 1862...1935 

   1 MYEMYGSPSYSLDSDLCVADGSTRCCPSCALPFSPGREVLSASIFCHHDEFIKRGNCRFV   60
  61 GHLTDEQWCSQPNLTPHRAKEGAPLVAAGEEKGEMPPRESLISRPLPSRPLPSRPLTISR  120
 121 REPHVQPDSASTSRKQTRRCLAEFINVETSPKGEKKGDAVGGKFQRGSPNDYLAGKQNRE  180
 181 EGARNVYRQEPSEGSGYEVESEPSKDVTTSLKWLFLNKKKNKGEENVRNNLSKNIEHTSE  240
 241 FIEKFNPMEKPTLPHILADQMFIITKNLLSTMEIKGNGLDKFKYQSILIYDSFENCKGTV  300
 301 RAQVYIQDVSPFRILTKNFMINKLGMFSICIEMEEVKYAALLKVQSNLIKQITPPNEAST  360
 361 VSAFNCALGKSAMLMPEESKVGIVEKIGENLSQKSYPYNILGKILWKEIKILACSSSENY  420
 421 IVILEMNYIIVVNSHLNAVHEIITHFLTKPVGIFLDNHIIYVTDADRKNVFRYMSEHILK  480
 481 TTAASLVFLDGSEQGEGGNGVKAPPPEYHTPGETNGRRTYARKKKRSYLSSLGRIFLEEK  540
 541 RSDHTDYLINGESYLITHLRDLYKVRRYKRNEAKLKGLLSKSVTMVYPAGIVVEKEKVYF  600
 601 VDTALHMLFCFSLKENRIVETFGYLNAPVMSDKGLNKPFSLALFHVTNWKKSLLFLSELS  660
 661 SSRILIFEINKSIKLYLTYSDLPLDIATSIVVTPQFLIVCGLKRSKENYVNYVTYVKIEE  720
 721 LCEFEIAYNEFEYALHYGQMVNMTPLKMSKNIKKFTLRQYENKTNQNIDTGLNINKHSGM  780
 781 ISGKVKISAWFHMEIVVYDYFKKITLNFQNFISSCPKGFFFESKNCVPCPIGHYTTFADR  840
 841 LKCTSCESYKKNSTTSYTGSISRNECLCKAGYYLKDNKRSCVKCPAGYYKDQVGDFKCQS  900
 901 TCENMKASIVEGAASYEELKCACKDGYYTDAQSKCVLCHLNNYCIYNPNAPIYKADVIPC  960
 961 KEHMVTLKRGSTSPKECICSVGYYYEKETDTCKPCSYDTYKPNQGNEECTPFVTNPVSTQ 1020
1021 EFLPNENYIEHSNVFLRKTSNVIISPKKGNSSFRSANFCETGYFYSKNKSICSICRYNGY 1080
1081 CKGLHNAVTVCPKNSVTVKLKSVTSLDCLCEKGYGRITINKHKLFNILCVPCPYNTFQPH 1140
1141 HSSGECIPCPAYTFTISVRSTSITDCLPQNGYYNMFFQYIYHHSMERLVQNVPRFLQQYR 1200
1201 HYLSGQYREGREAHLRGGQPSGGSHIDHVCEVPNEDSPLSLHHLTRKMTRGGKTHGDHEE 1260
1261 DHHNAQWKRYDKPHSTSGYKKDLAKARMPKISNSIRNLKGTYSNAFYTNYLKNVILMDSS 1320
1321 KMGRFIQQEGSIFSLANSPAGEVYPGGIPKDQREPRQEDTKGAPPKGESILMKDGTEHSP 1380
1381 VVPTAEEAASNAPDDRNSYLKGKALLSEEMKADVRKFNFIAEKKNDILTMIKTREETYIE 1440
1441 NRRKDISYECYEMERAIIIQKNVYVSTIPENDLISCLNTCISNIYCTGIEMDRTVGHGKT 1500
1501 DLLFFLNRSDGTKMLHFFKCHLYFYEEIESYYKKENLKRVEDIQQYDDADRITGCIVQKN 1560
1561 EMLKLWKVYNFDICPNNYYCPEKSFKKKKCPLNSVKKNFQGTIEDCLCSPGYSLQKNLNL 1620
1621 CVPCEKGTYKDSTSNGKCVKCPLNLTTSSEASSSQYDCVCREGYYFQGRFSMKLVDLKME 1680
1681 RAMIEGIKKTKENKISSLPSGQNKVEGLFFQVKSPRRRQKFAKMVQPLLGESPQGTTRER 1740
1741 EPPRGDNTSVIEENDVISTLERSFTQMGDTPVHVSQTPHAVQKHYNALPSVDFLSNKSDD 1800
1801 RVDGLLYGTCIKCPDKMFCPGFWYTNFERELHHPPIFCPKGSVVPKTTLESTDVHKCICG 1860
1861 KGYSINVQNGHHIRGSDGSDGSDGSDGSGGNGSSSEMCVKCQERYYKDVVDNSPCAGLCM 1920
1921 EFSTSFQGSISKKQCFCARGKYMIHESSHEMKCVNCSKGALCIGGLKYKSLKNLIQDSSY 1980
1981 TDIEIDDHVTPFPQKGYFATFELKHEDFAWSPLNSLNLQINNYDKGDIIIRNKIAKQLFG 2040
2041 RRISHLTVERSDPNGGITNHKMELKSGREKKLDYPPSKESISLVEAGITHILVNEKLEKL 2100
2101 KYKNEYLTVERIPDFHLCPISKRCVGGVDNMCAHGSEGYLCNNCSKGYDTIYFRSQCFKC 2160
2161 KKTKTELMDLLARKIFFYMIVFFLIYLNYFCYVKRNFVFIGIFKIWYFFIICFLPYIHIV 2220
2221 ESNHNSLPNHLFYFQFFITLPMRFLTHYLKLNCFVNSYSNQQYIHIWYIQRYIKIAEPMI 2280
2281 DCAVLTGVFLTIYLVYTRLKGKQISTVEKVIAKQINKVHSRGYYQHRSDFYYQYYQKHVI 2340
2341 DTINDKKAKEDWWSRKWANASFEREQSSCGEAAKGKVAKKPPHDSSTMGGNTTQCGSSAE 2400
2401 LSTSGDSLRAGKVAKKELSSSNENLYNFDEEFLPRDASNYCLKENIAKDKYWTYMCALNI 2460
2461 YNIRAFGLFRYIHPSSISTFSRLKRILSDLKVLYIIVLYIYFPFTLISLLELVWCQPVKY 2520
2521 KNKAPILILYHMPSQVCNWKNQLFASGVIFSSVFFLMYLLLFILSFYGTLKNFKIFGSYA 2580
2581 KRVRSYFLFNGYNYQNRCWDLFNVVKVMFVAISFTCQLYTKRSHNAKYFICCCIVFILIT 2640
2641 EVTLILMYSPYDKRSNNILRKLSLLSTFSILITYLSVQFSFFFNFPITNALPFVLFVYFH 2700
2701 LYMGNKIVLEFAIYRNIFKRKEEKEDQQDAGREAEGLLNEQSFFNFAKQKSSQNGVPLGL 2760
2761 HADDGDGSVPQNGCSDGGEKGKKKTSFPFFPLSSPYPSIFRHCNLCDLLLRANNIPFYSI 2820
2821 LFNEQGEEIFIFEKGPTKCKYEEIVKKVKMNTTERSQTGVISLDLLYYNIRDPSRQSLSN 2880
2881 VNYVDLNKSTTNWSQLMGEGKLSNNYEKFWKREKEYPREGDNYPHGEVDKENSRRAIPPI 2940
2941 NITHFINCLIEAINILFVNQSYNQISVEWISFVTRFSICFIHWMKNHDENLVNLVPVNKK 3000
3001 QFEMKKRNLLFYSLFSSYAEVYSLHSTIGDNNKFEEFKKNFVQAENLEQFYIYLNEANKK 3060
3061 SPGEKPAYRQSDDEEKSDCYTPLNFLDDEFYRCEQDIIKLLFDENIFKNLSISIVEFFFS 3120
3121 IYMIQFIESKRLSILIFLFCEKKNYLSREKQFLKMIEARKKDIQLIMYSQNNKQMYDFVE 3180
3181 NNYLNEYNRGLRKKIKKLQNLIRKKEKAALKQEEVKSVTRVQGNKANKISNANAYFVQTL 3240
3241 KKLLDDSSATARRHTGGAKRNPHERAPQ 3268

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 871...921 
  1 GtysnsglktCepCprGtYqpeegqdsCip.CPpgttTkstGatsesd..C  51
871 GYYLKDNKRSCVKCPAGYYKDQVGDFKCQStCENMKASIVEGAASYEElkC 921
Occurence 926...977 
  1 GtysnsgltCepCprGtY...qpeegqd..sCipCPpgttTkstGatsesdC  52
926 GYYTDAQSKCVLCHLNNYciyNPNAPIYkaDVIPCKEHMVTLKRGSTSPKEC 977
Occurence 982...1032 
   1 GtysnsglktCepCprGtYqpeegqdsCiPpg.knttTks..tGatsesdC   51
 982 GYYYEKETDTCKPCSYDTYKPNQGNEECTPFVtNPVSTQEflPNENYIEHS 1032
Occurence 1062...1108 
   1 GtysnsglktCepCprGtY.qpeegqdipCPpgttTkstGatsesdC   47
1062 GYFYSKNKSICSICRYNGYcKGLHNAVTVCPKNSVTVKLKSVTSLDC 1108
Occurence 1862...1935 
   1 Gtysn..........................sglktCepCprGtYqpeegqdpCPpg.kn   59
1862 GYSINvqnghhirgsdgsdgsdgsdgsggngSSSEMCVKCQERYYKDVVDNSPCAGLcME 1921

  61 ttTkstGatsesdC   74
1922 FSTSFQGSISKKQC 1935