Protein PVX_084580 (TriTrypDB link) - New domain MyTH4 (Pfam link)

Sequence and domain localizations (colored) at: 864...939 

   1 MDVNKNDEKNMNLDGLQVEASSKEEAIRVCTRIRPLFEKEINSGHLKAWKMNETDMQLVV   60
  61 EPLSLTEMINARVQKKGNKVEFKKNVEKSEGQKAVLQRYYAFDRCFDDNVGNEEVYKHLA  120
 121 RDIVLDTFKGINGCILAYGQTGSGKTHSVMGVPTDPGMLPRSLAEFFNGIENPSSLNEDN  180
 181 SDSINTDDEANNNTKEFLMSVTYLEVYMERVNDLLQEGYRGGATENLDVKEDPKRGFVVI  240
 241 GVQEETVTSIDEVMLLVAKAEQRRHISQTNFNETSSRSHTIFTVILESNQVLSDGTSINK  300
 301 RGELKIVDLAGNERAGRAAEGIENAKTLIEEGKAINKSLFVLSEVISKLSKRAQAIAAGD  360
 361 EKKIKKIQEDLVFIPWRDSKLTRILSKSLGGNCRASVIVAVHPSHFYLDTSFSTLRFALK  420
 421 CKTIKKKIEVNYLSAEQSVIMQQKELIAKLQNQLKHLATTKNVDSHLTGGEKNNVSARNP  480
 481 EDDEKILALKHELEEKVKKFQNFILKSELHVHPNNYRTLRSMDGNTEKSLKYSMTISNNI  540
 541 KNEYTWLRSFDTHEYESKWDGIDKYEDQNDQEHINISKAMDYLKNKPPYKLNSSEMSEDA  600
 601 MSNESQRDDLISLNYYNELEELERLEKNELSRRKRRERKERKGDAYVSTSNTSANRVYGE  660
 661 LSKLSSMEYSNLVDEEEKGDAAKGKKAKRKKGKRANNAEAKDTAKDTAKDTAKDTAKDTA  720
 721 KDTAKGKGNHLRKKKTANEGKLKRESFAKGDGAPKGGSQENGRSEGSDLDDHREVKRQTS  780
 781 PDSNRQTSREAKRQTSPDSNLQTSRDSNRQTSLEDDDLREREVKWEGGADLVRRASSVSF  840
 841 AQPREQDDNEKRTSIISNLKEKIEEDLKKKKKIISRNVELNKQIKFIMKLMQKVGLSTIL  900
 901 TGTVPPGRNIENVLQLQENLREELKLCDTKKSMELISGEKANHPTTGSPSASICANGDKD  960
 961 DSVAKRCHLSDRAVDMVEGEEELLTGAFDDDEHEAEYNESISHVFINEMFFSFVLRIQQR 1020
1021 NDPNGEELKNVEEVLKSEEKPYDVSKKALEDILGSTIANKADEHEEGNTTKNVKDERSSK 1080
1081 TIDSILTMLTPWEQKILALLYEQQKMRQTVQKIKEKFSQRIQHINIFIKKILTDKVEVEK 1140
1141 HFNRIIKATESYKNDLLKTADVDSNFKFAGMMKKLEELSISLAEKTRDFNVLAEFHLNLR 1200
1201 KQMEKKDSLIKELREENKLFYLVPKYNELLQELSAQDEETSQAGKELKREFLLMYGRLML 1260
1261 SRKRLQEKEVIENDMRNLNKKIYTELVESIAIIKNLESQNRFLEFKLNMENKKKGEKVKK 1320
1321 LMGEKEMLNKIVGEMEKMLEEANIDASEVKNQIVASYNNGNVSMLDLPSEDEGEQRERRK 1380
1381 ESGGKRKKRKEKEKGAATGKGKEKKKGAGKEKKKGTEQGGKKGGRVDANDEVPYDTQNDA 1440
1441 ERDSRKKNALQESAPREIAAKGKAPAKRQQKKEATVNRAYSAEKIIKKSVSRIDTNLSLK 1500
1501 RAGAKKGTSRDRGGLGGVSGASRLRESGRDGPLEKNAKLEINKKGVNKVKKKAGNDLGDA 1560
1561 GTSEKLKLKNSLAKKTGKKKTQYSDSEEVKPLGALNPSNSVVKKKHKKKTVKGKKRNLLK 1620
1621 YLNQGGSSRDRENLETVLSDENEFQDYKNGSSTTDCEANEMRNILNQEIEKKKKISK 1677

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 864...939 
  1 rsridlvqkIlkqgikrpeLiKQltkNPskqSalylctgtFpPSeellkyLslhrrcqer  59
864 EEDLKKKKKIISRNVELNKQIKFIMKLMQKVGLSTILTGTVPPGRNIENVLQLQENLREE 923

 61 LkiYktqkrlEieAik  76
924 LKLCDTKKSMELISGE 939