Protein PVX_086270 (PlasmoDB link) - New domain TPR_2 (Pfam link)

Sequence and domain localizations (colored) at: 540...573 / 780...813 

   1 MRSCSTASSGRKRKYDEVGSTEGEKLSGENIIRGKNKEGKEKRRSVSLSNAFFSAKSFDK   60
  61 YDNYFELARGDAADEEGGSTSGGEGISGGEGISVGEAIRVGASLTTNPPVNEILLHVKRF  120
 121 KFFLLKKSMVYKIRCLNHNSTWLSELSKGGGRGRRGGVNGGFLNDRLFVNPFPTYKEVVR  180
 181 LYYERKYKEAYIKLGLISVNSFSSPGEEDILRENYFGRKNYNLVFLLRSIGSTQKVNSPC  240
 241 GKDILKKKEKTKEKKKAQGKGKKNAISKRTSNGGSISADHKREKIIEKGNTLRMYMQSMK  300
 301 KKKKEEAERERKKKRIFIVRYKFVRYENDVNRWCDRYLQNGAFAVEGAAKVGGEKMKRCS  360
 361 CRRGGNISSPCRHHSNGGSKSEAIERNNYGVVPHGSSVNKPSGNLSEEELEMGGKENGDI  420
 421 NTQIERAPDGANLPNGKRSDKKKHSSFLNERIRGKTKVDTNLLVFLKMLCLYRYAHSFGE  480
 481 NKGLSLGGSISSTVHINRLEANGLTFLSQKVSIGTALQREILMYMVKYLRRVQKEINLDT  540
 541 HLCLLLSVVYYDLKKFHKSLLYVRKSIRRDYFNFVAWVLFNNLISLELFSRGGSRKGKMG  600
 601 RRKRELLRNPPQGCSRTGGSSYEAICEEKKRFRENSKKLKKLCSHLFRNGYFQSGKGDCL  660
 661 DAAEHYSRYIYVNPLRSSGPSFFFRNGYFVSRVFSAVGGEGPKKWNNPSGENLSRKTKPR  720
 721 NKKTHLAFFERYQGYLKRHKFRRNLMSLFGFAHFCSLNSLLYKDSIKTYKLLKGVLPNNF  780
 781 YVSCQLAKLYYYCGEVKKSMKCFAKMNRIYNRNVLLERSLLESCCVRYLQRRGKRGKEGA  840
 841 QTSGDSQPCIHAISAKKCREMEMLLLPGYFSKGFIYVELLVNMLVCEKDLPALLILLQDC  900
 901 ERAAGKCTGKSRGAKYDSTLCYIKGKYLSLCDNRKMSILCFKEGIKRNKYHLLSYMALAQ  960
 961 EYFSCGNVNSSVDILMKVISLYFNNPSAWFSLAKCFEWKENYRFSIFCYEQAITFQQSTI 1020
1021 FYIHLSGIYLKKGDVNGCIDTLKKGWRFKKDASLASTLFFLCLSKMKEQNGGRPFMGEEA 1080
1081 QEGSAPYHSKKERGKKKIFPFYEKNNECFRWGVKYLKCCFDKMKIMRRLNRGGCVSSVPK 1140
1141 LEAEEVGKCPHLGKAQLDDNAKSGAYDKWDGNSFLKNLKKIFEKNTSYFCFIHFLRNAST 1200
1201 TLFEAIYYLAHYFFFHERFYNALKLFEFFFLYFLFFFFLFPFGFSTNREVAVGPTLLPRW 1260
1261 VHFKWLIKPNWLDLSPLLFFFKKDSPVYTLQSVGKKMLNLKVAFFLSACILLFPRYGARR 1320
1321 DAQSYEDTPGASSHGDKSLEAKQTNPWGWGNNQTGKLFGSGANKENDSNERKHQVSFFFS 1380
1381 DSKGIPYEGNNLPSQNMCALQEYQNVNRCGSAHERMIQLNDARPYRFSGGNFSPLLHTNR 1440
1441 GTTKQTSQRGERKFDQLLLLLRNVIPFNMAPKKEMTQRRHKNCITVGESVKSKSVFKFLE 1500
1501 DEGMKRAVGTYHTRYKEETAILFAYEEVKRMMSGARKSRILREACTLDCGIDGTCEMNSG 1560
1561 LQYCECKAGYSMDIKNNFICKEHCAVNNGGCDPNAVCTPVVPDDEEKNGVIKNVGVLCKC 1620
1621 KNGNTKHMGYYCNSGYFTSLNLLLLLLLLLYWCY 1654

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 540...573 
  1 aealynlGlayyklgdyeeAleayekAleldPnn  34
540 THLCLLLSVVYYDLKKFHKSLLYVRKSIRRDYFN 573
Occurence 780...813 
  1 aealynlGlayyklgdyeeAleayekAleldPnn  34
780 FYVSCQLAKLYYYCGEVKKSMKCFAKMNRIYNRN 813