Protein PVX_087105 (PlasmoDB link) - New domain CBS (Pfam link)

Sequence and domain localizations (colored) at: 216...835 

   1 MQLWLLITGIVVCGILSALFSGLSLGIMMLDTLQLNLLILVSEKDKKELNNAKNARKILP   60
  61 LRNNTNEILVTFITANVMVNSAFSLLLSELTDGVTSFIISTLIITIFGEIIPQSICSKHG  120
 121 LAIGGFFAPLIHCLKFCLFIFAKPTSLILDHFVGTSAVGEGKRKNGRTNVLNTYNKKQLK  180
 181 ALVDVHKSAADILHEDEAKIVVSALEMSQYKVMHIMTDIDYVFGIDYNSFINYETIKRIL  240
 241 KSGFSRIPVLNRCNSECVVGLIHIKDLINIWFGINKIIFDNNSLVQCRKRRDTSKHRYFK  300
 301 KRSRTGIFHLIKMKSEKIRIANKIYAYDGARILGRCSASNRGDDAPRRASQSTTTCSKRR  360
 361 RKIPVNAHPSGQKPNGYDTDTADDENDWDSTLGKENGAEGADDAANRGDPSANGEEDDPQ  420
 421 DGVEVVDLKGGAEGHLSTDSEVEPAQEASNPDEVKINIDERPHRRGTKQENRTKQDNTAK  480
 481 QAKPAKQTNARGDQVGGCASNSDREKKKKKKVQIHVEGEEPRAGCGGYYDGEGGGRGGSD  540
 541 KRGGLDEIVSPSKLRERKKKKVKKTYKNPYEHKNRNVNFVEFLSDQMMLNGEDEQESSSP  600
 601 DEVVFTDIQKRIKYYSRMNKGGGGDANGVAAKALQGKPRPEKGKPAKWEKSGQSGPGTKG  660
 661 ATPPSGSPSDGGDRGNAAHAGGNAAHTRGNAAHTRGSTTHTRGSTTHTRGSAAHSSISDI  720
 721 ASNHGRNRYISQSIMIKENLNKEKNMQHIFLDIKNYIRIARNKDIEIPVKYILKHIGRYI  780
 781 YGVDYNESILSLLSFFKSANNHIVVVRKVIYDEHADPKYAHIGIITLEDVIEILLQEEIT  840
 841 DEFDFRSVKKGTDIPSNFVWKNSDESIGRAKQQGEPLRGEPPQGEPSQGEPSQDIPPQGE  900
 901 PSKGEPSKGEPLPNQSPSPHSSHSSYSPPSPATPPQRARPARKQTLMPSCKREVISFLKE  960
 961 SVYFKYIDTQLISKCIQRKKIKTAQKNEYILKENTFLNYAIILMKGHVKNIKNGSTNVLA 1020
1021 HRCIIALEALGPCNIIELFNSTIEKRINVLKNYEEEKKKKKKKKSLFFKRKSSDDKKDSL 1080
1081 RPKWTTSLSRDNRSVHPKMEHSNMGSNIGSAMGSATGSAMGSGLSSHPSGGLRSGLAKTN 1140
1141 SHVIHKNINILFKKWYTQHVYFNKSACIAETPCEYMILSKNEYMDMIIECYSNNKVDEII 1200
1201 EDN 1203

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 216...835 
  1 dvmtkdvvtvdpdttl..ealklmrengisrlPVvd..edgklvGivterDllrala...  59
216 MTDIDYVFGIDYNSFInyETIKRILKSGFSRIPVLNrcNSECVVGLIHIKDLINIWFgin 275

 61 ............................................................ 119
276 kiifdnnslvqcrkrrdtskhryfkkrsrtgifhlikmksekiriankiyaydgarilgr 335

121 ............................................................ 179
336 csasnrgddaprrasqstttcskrrrkipvnahpsgqkpngydtdtaddendwdstlgke 395

181 ............................................................ 239
396 ngaegaddaanrgdpsangeeddpqdgvevvdlkggaeghlstdsevepaqeasnpdevk 455

241 ............................................................ 299
456 iniderphrrgtkqenrtkqdntakqakpakqtnargdqvggcasnsdrekkkkkkvqih 515

301 ............................................................ 359
516 vegeepragcggyydgegggrggsdkrggldeivspsklrerkkkkvkktyknpyehknr 575

361 ............................................................ 419
576 nvnfveflsdqmmlngedeqessspdevvftdiqkrikyysrmnkggggdangvaakalq 635

421 ............................................................ 479
636 gkprpekgkpakweksgqsgpgtkgatppsgspsdggdrgnaahaggnaahtrgnaahtr 695

481 ............................................................ 539
696 gstthtrgstthtrgsaahssisdiasnhgrnryisqsimikenlnkeknmqhifldikn 755

541 ...........tpvsdiMtrn..pvitvppdtsl.ealelmlehgihrlpVv....Dedg 599
756 yiriarnkdieIPVKYILKHIgrYIYGVDYNESIlSLLSFFKSANNHIVVVRkviyDEHA 815

601 klv....GivtreDilrala 620
816 DPKyahiGIITLEDVIEILL 835