Protein PVX_091905 (PlasmoDB link) - New domain Kelch_1 (Pfam link)

Sequence and domain localizations (colored) at: 139...184 / 248...299 / 305...355 

  1 MTSSNKFLNIKKEDSYLAKFTHDTIIFAENLFKIIAKPFTHGGSSALEEYADDGNVEAIS  60
 61 FCSEVLPFYCKSELIHRGDIFNVRFGHSCIFYKNSIYIYGGNQLSESFNSKLIKFSTETQ 120
121 IFSLVEGQTPPQSRYYATLNLVYSSALSEHCLFLFGGKRGKYITNDTYLFNLSNNSWKHM 180
181 KVQFSPPPVFGHVSFKYKNIIFIHGGNMGNLNVNNDIWCYFEEEKKWVKIMSKDEYYKKE 240
241 VYKPSARFFHSCSVCISNQGNDVRAFIFGGLNANNKCAEDTFWCYSLGNGKWTPIENSLG 300
301 KVPVERFGHSSTVLNDRWFLLCGGYNFCWYSKSELLDIHAYDINLNTWSSLNVYGTPLVT 360
361 HHFYGKIIQVDESGYFFIFGGLRNNETSSKIYKFTPLLASPYFKLLRDKIDEMERKVLYL 420
421 EKNPLQLLNPSYGRDINEIKGTLSGISFTLVRYIQLASDINEKIKISNELAQSNYPQLAE 480
481 KFEQYNKQYDSLVNRIDLLDSTLSVSDLDVRGGNENNLRKSSSSFTLSSEVSGEGSGQQS 540
541 EQQSGQQGGQQRRSAERSADQRVVMPSAGGGGHTFTMRNAPSTGLPSLTLPSQQ 594

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 139...184 
  1 pRsgagvvvldgkiYviGGydg.qslnsvevYDpetntWtrlpsmp  46
139 LNLVYSSALSEHCLFLFGGKRGkYITNDTYLFNLSNNSWKHMKVQF 184
Occurence 248...299 
  1 pRsgagvvvldg....kiYviGGydg...qslnsvevYDpetntWtrlpsmp  52
248 FFHSCSVCISNQgndvRAFIFGGLNAnnkCAEDTFWCYSLGNGKWTPIENSL 299
Occurence 305...355 
  1 pRsgagvvvldgk.iYviGGydg.....qslnsvevYDpetntWtrlpsmp  51
305 ERFGHSSTVLNDRwFLLCGGYNFcwyskSELLDIHAYDINLNTWSSLNVYG 355