Protein PVX_092035 (PlasmoDB link) - New domain PFK (Pfam link)

Sequence and domain localizations (colored) at: 163...506 

   1 MDIENAKKHLSDLQKERRKKKIALPRVFKGKALIREEHEQRHEKRHEQRQAEQKSLGGEC   60
  61 PRGDALEKHFPYIFKKPVIYLCAEKGEAGKPVGKPVGKPVGGVADALANRGDDALPTALP  120
 121 NGINIKESLDEADSAKLLDGNCAGNSATQELLEMNAEDGDTLNLGVLFTGLPAPGGHNVI  180
 181 CGVLDSLKKKNRKNTLFGFLNGFEGVKSYSFMELKNEYISMFRNSGGFDMLRSSSFDSLS  240
 241 ESGKRKCFKICRQLNLAGLIIVGGVDSQRQVASLAEYFEQVHVLAGLAAEGEVATAPLDG  300
 301 GVAHEPLDGGVTHAPRDGDDPTYQIVSDLSDEEIKAKYPRRGKKRSKRKTCVVCAPKSVC  360
 361 NEMDSDLVECSLGFDTTVFTCCQYISFLTSHVRTYQSGYHFVRVIGNSSSHVALECFLQT  420
 421 KANIVLISEEIKKKKKKLKDVIDFIVHVVQRRYHLLGRSYGIVIVPEGLLGKIEEFKKMV  480
 481 RGLLLARKRALQDGQHAEDGAGRIVAQFYEESAESAESAELFRSLPAFFQKHLLEEVQSE  540
 541 RFQYARLKTEELLLSCVKEKIEQTKMKGIHFASHAYTKEVTCSLPSNFDCAYSYLLGMGC  600
 601 VEIAQSSYNGYLCTIRQLKNLIPSVEKVQVVGVPLCRLLRVKGEPQEGRNLTEEHEEGHN  660
 661 LMVAPEGSSHIGSAANPSEDLDRLEKSVSAKRAKVKLNGGYFLTYKKHRAALLYADAYRT  720
 721 HGGIQFERSVADDGEEHSADSPSKLKKLFSSTFSTWDSKWGELFNRVNFTVSGLSGGLMR  780
 781 HNSQVVYVDSHFASKLSYTPFEHIQKITDFYVVKAPQVNVKGRVRCSESFISEERNVGVV  840
 841 LLSHSVPGVNNILAGLHERLSMNNIKLIAFVRGIRGLLTNETYVVKDSHLGSWKNLGGAP  900
 901 LLGVQLEWRKDDGEVVRLNNLVEEKYIKEIIITCKKNKMTHLVFIGDEKVITIMNILNDH  960
 961 FMKNRTNLQITTVPVSLYNSFYANLIECSIGYHSMVYTMSDLIGNLQSCAVNAGSYYCFV 1020
1021 KVPTNLSSLSVLSIQLETHCNVCLVGECVEYQMMSLQDLVEQTCSIIIERINRGKFYGTI 1080
1081 LFSSNLLLNVSDFSRLVADVEEHVRGGDALDRLIDGPDLPDLPEGLSQESAELLRICTKS 1140
1141 VREKLLRKENRHDDQVDCNFEDVFVEQIKRHIGKLTEQAKQANEPYSFDAHMSYLRANGM 1200
1201 PKNVKLYSDLNYMQHFNCVVRNIDREINCCIPTHLDNSLAFSHGLLAGIAIENDLANYVT 1260
1261 SIRHLHLNKKNWSSSLYPGSYFVNRDDAGGVAGYPYAAPVPVSVKSSQMATIKHNAETWA 1320
1321 YNDCYIFVGPYQHEVNADSPGCSAHMF 1347

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 163...506 
  1 kIgVLTSGGDApGMNAAiRAVVRsAiaeGle..VygIyeGYaGLvaGnIkqlewesVsdi  59
163 NLGVLFTGLPAPGGHNVICGVLDSLKKKNRKntLFGFLNGFEGVKSYSFMELKNEYISMF 222

 61 iqrGGTilgRcpEF..rerEGRlkAaenLkkhGIdaLVVIGGDGSytG....AdlLtsEh 119
223 RNSGGFDMLRSSSFdsLSESGKRKCFKICRQLNLAGLIIVGGVDSQRQvaslAEYFEQVH 282

121 gleeLvkeGki.....................................teeevaky.... 179
283 VLAGLAAEGEVatapldggvahepldggvthaprdgddptyqivsdlsDEEIKAKYprrg 342

181 .....qylnivGlpGTIDNDisG..TDyTIGfdTAlntiveaIDrIrSHqRtF.....VV 239
343 kkrskRKTCVVCAPKSVCNEMDSdlVECSLGFDTTVFTCCQYISFLTSHVRTYqsgyhFV 402

241 EVMGRhCGdlALvaGiAgGADyIvIPEapApedfweeelanrlkrgrer.....GKrhnI 299
403 RVIGNSSSHVALECFLQTKANIVLISEEIKKKKKKLKDVIDFIVHVVQRryhllGRSYGI 462

301 viVAEgaigkpseavkklkvegfDRiLASrmGaeAVe...aLLe 344
463 VIVPEGLLGKIEEFKKMVRGLLLARKRALQDGQHAEDgagRIVA 506