Protein PVX_092430 (TriTrypDB link) - New domain Excalibur (Pfam link)

Sequence and domain localizations (colored) at: 183...252 

   1 MERLNGIVKQVVSADTYVLAGAKKGGVAQERQVSLACIQCPRLFMKSQNVEKSEEAFAWE   60
  61 SREFIRKMIIGKNVSFVVEYVYNNRTYCSVFYEEQNLSVLLLERGYANLVSNKNVKTNVY  120
 121 ADLESYYVEAKEKKLGIFGSNVNSYVRNIVYSYNDKNQNKKIFELFSNRKLQCVVEHVRD  180
 181 GSNFRVYAEVEASDKREVGISTPGGTSTSLQNGTVGESLSGGKGKKKKKGASGKKNPKNK  240
 241 DGAEDSDGDDVAKATAGGYKTMYYFSFTLCGIIVDMFKKEVVNNVENVKEEQYAMETKKF  300
 301 VEARLLNRDIEIVIKHIDNNCNLYANVFYKLGNICTLLLKNGYAYINDYTIKYVENAIDY  360
 361 KRALDEAIQQRKKKWVNYTEKKVDYEKEYLATVIEVLYGDVIIVDYHNEERRLYMASIKC  420
 421 EKHSTDLALNTLCLSAKDYLKSQITGEVVKIVTEYVRTPQSNSEGYIPQCSDDKGRMHFV  480
 481 SVYKMENKKKKESAKGGAALPSSKWGGEGDEKKKKKKNAKKGGATTTGESNSVGKKKGIQ  540
 541 MNGHAGTHAETHAGDENGEEDDQTVTNMNEQLVARGLAKVMNHRQEDEKASNYFKLQELE  600
 601 KEAEEKKVGRFNPHLDIIKINNISGSENSLRARSFENVLNKYNNLNASVDYIYGANKFKL  660
 661 HIPSQNLLINFILLGISVQKINLKEIGSMNTSAVQVKKLSAGGGEYDGEDAHNLVNGDGK  720
 721 PNRKEKLELKEIAIQAYKYTRKMLMQRNVQITILTCDKGGNFIGILRHQNKDFGVHLLSL  780
 781 GYGMLNEIGLSNTNERNNYVKAVEEAKKEKRNIWAIEKIDANEDDADNVLLNGQKNLSQF  840
 841 DNIYYCSYVEDINNISIQLKSKQEQLKKLQDELNKPANLESSSQYVLSEIKKNTLVIAKY  900
 901 IDKCYYRAVILQINKAKKKALVKYIDFGNEDELNFEDIRKLSDGLSLKSYPPFSIRVSLA  960
 961 GVKIPAENKSDLIIYVKKFLLDKFLYVKFEKKERNGAYYHVVFYDYEQFTTNKNVKSVNE 1020
1021 DIVSSGICYVDNRSDTKIFEKLKKEEVVAKKAKLVIWAYGDIDYDDES 1068

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 183...252 
  1 gyknCsemrsageAqiylgqpggtphkL................................  59
183 NFRVYAEVEASDKREVGISTPGGTSTSLqngtvgeslsggkgkkkkkgasgkknpknkdg 242

 61 ..DrDgDGiA  70
243 aeDSDGDDVA 252