Protein PVX_096410 (PlasmoDB link) - New domain GCC2_GCC3 (Pfam link)

Sequence and domain localizations (colored) at: 1000...1051 / 1056...1105 / 1110...1159 / 1243...1300 / 1305...1355 / 1360...1421 / 1542...1593 

   1 MVNPSKFFFFSSVLVTCLLKSEAASNGKPGFGKEPTVAPPKKTKESGEYRRSAAVKLDKL   60
  61 KFKRAPRNILKAKKRGINFVSLNLEKVIELKQKDPLILISSIYSGEKEKFLSACYENGKI  120
 121 KEGSTCSRITTTKEICDVPVDFNLDYVFSYRDRNELPSKCLVDNVPQYRIKNRDHVVVQS  180
 181 GEHFDLKIMNESMLLRTSVIITTGECSDMVKSRSTLFQFERSPNPFGDPVLHKGEVIGSE  240
 241 FKNIYVNQEAKGVFNICSCYIDYLDINYNSCLLASRHYTHIYTLRAILPSSKIITLNTGE  300
 301 KMTIHLKEYETMFPIQNAFIIERVSGYQCSNINKKPFTQVQEDFYQNVRRLNFYDVYLYE  360
 361 MGPNEIIEDVVFGKPGSYLLCYTSIDRGTEFSSLLATIHVKGYFLNVVNYLYVDLHSTKL  420
 421 KLGHSIFLKRMGIEPLSKVVFKKREAENCSGEIIYSNDALEIIVEEKGNIKVDIFQVSDI  480
 481 KLSEYNELLDICSGEKGKYRLIGRAQSKPYILNTHENVFLLKDFKFPPDDVRTYVMKKES  540
 541 HFFKFYPYLLEYSLKNKVDILYVSFMCYSSSNEISITYSSDRNMTPKSFAQFKITQASSS  600
 601 VLYVTSEEVKIYVLKKNLQSLYMYDITPSKVKMRKKSTQRYVDDPHMYPLLNFYSDYAYF  660
 661 VKCNNCSTPILMEPVYDENKKLKLLFLVTSDPLRRIIIVNLKFSIVYVHNTNAVKNKFEE  720
 721 INELRFGLDVLKDSSYLITDVSCGKLKNKSFDCFLVDQMNNSVIALHYIQKRKLLLRMDT  780
 781 FQGESNASDENAYVYNFIFSQSDTYLQNPKHVVPFPYGDSYVLFVDEDETTEMNIILYNR  840
 841 NKPSKRFSYVSKINSTYIDEGKINKIYKFYDHKELINRNVLLIVKELENAVHFVIAPIQN  900
 901 ITNVTELKYTYPSIVQDNGIPYALKIKSDEIKKMNLLHNFQIEVHNANKSKHVAIDKYDG  960
 961 TIVIKLSEFIDDPVDLTAKMYGVFMELNTNIEITVICADGMKALNGGCVACPLGTYNNIN 1020
1021 EYMKHGNMHECTKCQENSITKNEGSTSIAQCLCLPGYELNNNDECVPCAMGTWKSETSNT 1080
1081 PCIFHCYPNSQSLIRGSRSEEESECKCLKGYYFVSKDGINFCEQCDIGHFCPGGYRGAKK 1140
1141 KCPENTTNEELENFSIKSCKCNAGFEPFDSSNLNNYDFRTNPIFDDYKDFEQEMEPSHVC 1200
1201 EPCKMGSYKNTVSEEKCKRCSAHVYTDAIQSTSIAECKKCEKGYYLHEQDLCLLCPDNHY 1260
1261 CPGYPAEDKKYSLYENQKVPCDDKTLTIPPNELNVSPLNCLCKKGFEYVKSEENEFACLE 1320
1321 VPKNYYKSELSNTQKKPCPENSVTLYTQTKSKIKCICVGGYYWDINENKCIKCPKGYYCP 1380
1381 GGHLKDCFLQNTLHLCKPKKIKCPIKNTTTKAEESFSESSCLCDKGYTLSKESLRECVLC 1440
1441 PVNTYKDFVSNAECTMCLTPYTTDGQVGNAKEEDCTCSGGYYFFNHCIPCSDKNTYCKGG 1500
1501 KMIVNNKSKTIHYGPSKCPPNTVVSFETERPHNQSFCVCKKGYKHVYTASNYTKICAPCG 1560
1561 RGFFKTMIGDFSCESKCKPNSTSLTGTTHETHCFCLTNYYFKNGICVNCPDGAYCEGGFE 1620
1621 EETLLIMKKSVNSLDPSKIKHVMPVPKENYALYKLKGNIYNTDWFIVECPIKEACLYNEK 1680
1681 CHESMTNFLCGECKKGYTNNFSKLNLCIECSGNIMNILHIIFVSIFVLLFTVIMAYLNVF 1740
1741 TGANRKSVHSIVIKIALNYFSCMKIFYVMGTSELYFPLNFSSHVNYIIQSIKTLLKAKKN 1800
1801 YGPYCILTTYFNFSHSDAYYYGMLFYALRPILLAITLTILMYLMVEIYKFKVRDQTRIKL 1860
1861 NVVDKIKELGKTKLYEEIMQELPSERGLVLFRYIPIPGDSKFKRIKKFLEDMIPMYVTLL 1920
1921 FFIHTKTTYAMLTLLDCKAIYYNDKFVEQYMSYAPSVKCDMSGDYAKFFMLGIIGIVVWG 1980
1981 IGIPLMSYLVLYKNRKHLHSENILFKYGFLNNGFNFQFWYWESIVFFRKILILLISSVPI 2040
2041 FKTARIFGTTMWLFTVISFFFLTVQIILQPFDSRNYHILNKLETYSMFAWTITLMTFVFL 2100
2101 TVSSADATINFYVLLFLLFFNFIFVAKVLIALCYSYIENLRHIKKHVKIPILSNFFEKMA 2160
2161 KIAEEKYYKEPIVSLNTRDNSIQFMRKYKRYPLRKHRLLTNEEKNYFLNVLSNFIYFGVS 2220
2221 NLNFTIFHSHFMEFMLRLSVIDNEMLHKKGKRGILKLIAKDPKNIDEWIKIKESELNKST 2280
2281 FFERHKKILNLFTKNMLIIQNNIKSIIYQGDKHTIISDYEVLINVLKYDEDFITDFKFLY 2340
2341 DENAVKSGLTLSDLQLSFTKIKMKDKGLIMQLFSLFIAKKNIVQFERDIHLKNKIEQLKT 2400
2401 LYDILITANEKKKITFRKNFEDAVKADPFDYRTLQNELGALNERINNLIDDYQKLKDANY 2460
2461 YEDECDSNNNVALNNDSEFFDNNLKELSFKEVTNDEQSIENAEEGDNNIQNEETNAENVG 2520
2521 NEDGKEENKMKEQKRS 2536

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 1000...1051 
   1 GtysnsglCepCprGtY......qpeegqdsCipCPpgttTkstGatsesdC   52
1000 GMKALNGGCVACPLGTYnnineyMKHGNMHECTKCQENSITKNEGSTSIAQC 1051
Occurence 1056...1105 
   1 GtysnsgltCepCprGtYqpeegqdsCi.pCPpgttTkstGats..esdC   50
1056 GYELNNNDECVPCAMGTWKSETSNTPCIfHCYPNSQSLIRGSRSeeESEC 1105
Occurence 1110...1159 
   1 Gtysnsgl..ktCepCprGtYqpeegqdsCipCPpgttTkstGatsesdC   50
1110 GYYFVSKDgiNFCEQCDIGHFCPGGYRGAKKKCPENTTNEELENFSIKSC 1159
Occurence 1243...1300 
   1 GtyssglktCepCprGtY...........qpeegqdipCPpgttTkstGatses..dC   58
1243 GYYLHEQDLCLLCPDNHYcpgypaedkkySLYENQKVPCDDKTLTIPPNELNVSplNC 1300
Occurence 1305...1355 
   1 Gtysnsgl...ktCepCprGtYqpeegqdsCipCPpgttTkstGatsesdC   51
1305 GFEYVKSEeneFACLEVPKNYYKSELSNTQKKPCPENSVTLYTQTKSKIKC 1355
Occurence 1360...1421 
   1 GtysnsglktCepCprGtY...........qpeegqd..sCipCPpgnttTkstGatses   59
1360 GYYWDINENKCIKCPKGYYcpgghlkdcflQNTLHLCkpKKIKCPIKNTTTKAEESFSES 1419

  61 dC   62
1420 SC 1421
Occurence 1542...1593 
   1 Gtysnsgl....ktCepCprGtYqpeegqdsCi.pCPpgtTkstGatsesdC   52
1542 GYKHVYTAsnytKICAPCGRGFFKTMIGDFSCEsKCKPNSTSLTGTTHETHC 1593