Protein PVX_101240 (TriTrypDB link) - New domain Mad3_BUB1_II (Pfam link)

Sequence and domain localizations (colored) at: 359...428 

  1 MSHMKFFKYFSEKNRQKNNAPPEGSCGMSFHKKRFRKYLNFLITRTKGKSKKIITNKKNS  60
 61 LEEDEQRGEKNGCIPPIENSNAQQKSIKMDANGKHASKATSASYANKATSANYANKTNSA 120
121 SYANKANNANYASKANNANILKKKNFDDIFAPGKNLKMSKHSNCIMHKAGARSSVERTKL 180
181 FKLNYDYHNKRRGHLFKFPFLKRNNCKGEEIEDFIHMNTTAGLEFSTDAQMNNYKNQVDR 240
241 YACAHSYGNRNICKMYAKGGKFQNSKNTFGESGENGDMFTNNMYMYAKTILEDEGRGGLH 300
301 KQKSGTPLKKAQAAKSPKFKAFKSNYWTFRSSAKNKPREEEAARQGDGLTSNPNGNVCYK 360
361 DNMANAANISNTTNFTLMNRKDKSSRVFKLNDDCLFLHDEYEKQKKGRFRKTLSLSYGRR 420
421 KKSLRPDNFTFLKVIGRGSYGKVLLVKHTQNNKLYAMKILRKENIISRNQLEHTKIERNV 480
481 LKCVSHPFIVKLYYAFQTTKKLYFILEYCPGGELFFHLSKMRELTEEAAIFYTAEIILAL 540
541 QYLHKLNIIYRDVKPENVLLDEMGHIRLTDFGLSKEGISDNNSARSLCGTPEYLAPEIID 600
601 QCGHGKAVDWWSLGIMLYEMLTGRLPFNSSSRAVLFERIKHETLRYPCFLSPDAVDLLKK 660
661 LFEKNPKKRLGSGVTDAEEIKNHPFFKNVNWDDVLNKKVKPPFKPPLFDQMDVQNFDKEF 720
721 LCMPLRYSDKFDSNPIAVKSQKSYMIKGFNYSLYD 755

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 359...428 
  1 FrDsladqAkgrsgpVYKLIenpGkKpEKIdcNfdLLY....PeddeKSSlsRnvSLGYk  59
359 YKDNMANAANISNTTNFTLMNRKDKSSRVFKLNDDCLFlhdeYEKQKKGRFRKTLSLSYG 418

 61 eqqnkvKtre  70
419 RRKKSLRPDN 428