Protein PY00334 (PlasmoDB link) - New domain PI3K_C2 (Pfam link)

Sequence and domain localizations (colored) at: 6...189 

   1 MVEGKKPNKFCITCYLIIDNEFFSYPVTXECDEIKIRSESDXXXIKKKRERKIDINIEKK   60
  61 KKEEFLDPIDMFIEKKKKKIANKIFIINKRICFPLRYRQLSTNSYLLFIFQNKNNTDVSY  120
 121 YSFCKLFTQNGVLKQGLQIRHMYYTGNSNKNKNSKNSKNSKNSKNSKNNKNNNNIIASKT  180
 181 AHRVNRHVTEALKRNIIYIKSDSKNKSKQSLFRFLKNNYAYNNLLNLCDLKKKYIKKEKY  240
 241 TFGKNNAKTKLIAHTKFSTDKFIIKKKKNKVNLIRPNYKFKSYIKKVLQNDSMIQQIKQK  300
 301 RKDEKINSLGNNLYDNNQDIQNNAKTINSFNMGLFRGETYCNYTITSKKNKKNYLNLLKY  360
 361 KHMVHFIYSLKRNMIKNYKTLEKKKLIYEKEIENEKIDKNNHQIREIGYIKYEVNRNKKC  420
 421 RAFTSLSEINKKKDVNFSNNMMDICWIKNKNLLKWKNGYSYIKKYSYLYDLHNGRISNVG  480
 481 NRNSFKLLKGVINIYKKFKIFKEKKIKGYLIFNCVSFNKPKICYNEKKKKLITFHENIFN  540
 541 DIENKEIGSPNFYHNTGSNYDWXFNSFDYVGDTSNINNLSFNKFVKSVAKGQKKNKHGNL  600
 601 FLHNFIFDNKKDNIINEKNKNYSHNRFKIIESKKYCGKIKNILYKRNSVDVLRNVNTNHR  660
 661 HTEKKINDIFDHISKYTNRISKNINISNINRYDDYPFNFFSKEKCEKKKISVTTPPIDEI  720
 721 KTLNYVLSIPLTKINDDGKKCLWKFRLFLVNRKETLGKFIKSVNWNDKNEEKEAISLLRK  780
 781 WSKPSLENCLELFHLYMHYNVIKKYIIDIIKNAKKEQLKLYLFQIVQRLRTFNYQRIDDL  840
 841 FIDILIHKCVKSKKLSIYLYWFLLSETQDKNNGKLYLHVHKLFINKLVKSNSKKKKKILE  900
 901 ILKNQNRFRNQLLYLTIIAKNKSDHIQNKTKKIRKNLFYYRQCFGYINIKNFIKNNIFIT  960
 961 DQNVYNFSHTSESQKYDDHIYSNPMDPNFLNSSIIEKELHQNASTNLSSTFISSNTSLIN 1020
1021 QNEENVSLKKKNNFKMIPNDLCNSIYYLSPELTIHFNAEEDKYAFQYERKCNMSDEYINN 1080
1081 NAMSNVNHNRNRDNDFENENNGYVINYIDDSKIVKIEKNKDSSFFYNFLQPNDGFGFFLN 1140
1141 YSDDDKNIEILDDSINIVQEQKIKKVTTPLILPIDPNTELLTFLPEHSYVLRSSLYPIVI 1200
1201 ACLVRKKIKLFHSDFHNLIINKQKYLKKNIKKKKKNYSLYHFNDSKFIKALYNSFDKAKD 1260
1261 FQYYYKNIKCVNNVIFYKKQKIERINNPSQNNEPFIDGKKQQTQMRKDILKEMQIKISTD 1320
1321 DGQCNNDDSIADVNEHFGEFDYTFNPDFSHFENKKTDNNSVITTPTSRPVLKKKNEINNL 1380
1381 DISDSKLYEKEKEASNDHLEKEFVQKEKQNSINKKRVKKYNEIYELTIKKYIYKAGDDLR 1440
1441 QDHLVIQVIYIIDNIWKKYGLNLKLTLYRVLALSTNDGFIEFVDYAESISSIKKNYNGEI 1500
1501 RQYFIHHSNEKNTPLGFDTEILENFISSCAGYSVITYILGIGDRHLDNLMVSNDGRFFHI 1560
1561 DFGYIFGEDPKPFSPPMKLCKEMIEAMGGAQSVGYEQFLKKCCLAYKYLRYHSTLIISLL 1620
1621 DSMCESGLKDMKTAPELCVLKVQEKFRLDLNDEAAEIQFLEVINASVKTLFPVVVDKLHE 1680
1681 WALNWK 1686

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 6...189 
  1 kysdlyvecslyhggkpLc.........................................  59
  6 KPNKFCITCYLIIDNEFFSypvtxecdeikirsesdxxxikkkrerkidiniekkkkeef  65

 61 ....lpvqsTsykpfsfssvkWnewltFpikisdLPrdArLvltlyeisgksksGwvnls 119
 66 ldpiDMFIEKKKKKIANKIFIINKRICFPLRYRQLSTNSYLLFIFQNKNNTDVSYYSFCK 125

121 LFdkkgiLrqGpqlLslWpskepdgsvpqlalrdelnrLekllkkyerGdvqspsvlwlD 179
126 LFTQNGVLKQGLQIRHMYYTGNSNKNKNSKNSKNSKNSKNSKNNKNNNNIIASKTAHRVN 185

181 fltl 184
186 RHVT 189