Protein PY01039 (PlasmoDB link) - New domain WD40 (Pfam link)

Sequence and domain localizations (colored) at: 1546...1589 / 1804...1847 / 1861...1899 / 1905...1943 

   1 MCIYICMCLHFSDIFNSNGLSAPPDLTKLTHLHEASVLHSLNIRFDIDEIYTFTGPILIA   60
  61 INPFKHIKNLYSDNILEKHIQPIKSKSPHIFATSNSAYLGMCKNNKSQTILISGESGAGK  120
 121 TESTKYVMKFLACAGSDIKKRSLIESQVLESNPLLEAFGNAKTLRNNNSSRFGKYIELHF  180
 181 DICNNGYVKGKLYGAKILTYLLEKVRVCDQQEGERNYHIFYQLCSAVQYYKNKKLNLEND  240
 241 DNNYDDEYYYFPSCDKFKQKENVKQIKINLKKFKDHLNFRYLTKSSVYELNDVNELEEFE  300
 301 STVYAMQVVGIEENEQNQIFKILEGILYIGNILFNNDDNKEESSILESTYEDLKNAAYLL  360
 361 DIDADTLKDALCYKTIIANNEHYKKPVTSAMASDIRDALARAIYGCLFLKLVERTNESIG  420
 421 LIKDVNLFCGVLDIFGFESFPVNSFEQLCINYTNECLQYFFNNFIFKCEEKLYIEEGIKW  480
 481 SSLDFPDNKDCVDILQNKPFGIFCMLDEESFIPGGKDKTFCNKIISKHVNNKRFESIKTD  540
 541 PNSFIIVHFAGKVMYNSCGFLEKNKDQLSDDAQNVLLKSQNEYIHNLFKKYLRRNFEKKR  600
 601 FATVSSEFKQQLDVLMTRINQTEPHFIRCIKPNSKNVPDIFDRHSVNEQLKYGGVLQAIK  660
 661 VSRAGYPVRLTHQNCINEYYILLTKDEKINFSKYYGDKSLSEKANYILSKLENREKIQDY  720
 721 MKSLKHIRQKKNQENIFYGSVLKKQYTKNSNLIEKKNNTRYENNTLNDIIEDDKFIWYVG  780
 781 KTLSFFKIEAYNILLTMRQDFRSLNAIIIQKNYKCYIEKKKYKLLKKKIITIQRWIRNVL  840
 841 TILKKKKIIMINAQELICSYIYTYALRKKFLYKKKCAIIIQSAFRGYLIRQSYKIYRTNY  900
 901 YASKIQAMWKCKKERIKYLKLIESTKKIQLKWKGILARXQLRRLKDEAKEVGALLSKNQI  960
 961 LMDELKNEKSEKFEIENKLLKASANSQKLTKRIEALEQINKNNELVIKNLVEKVEKLSLK 1020
1021 QKGEIAEKGAGKNAEENAGKNAEENAGKNISDNNKISRKQDSGSDHNLFKLLDKIKKLEI 1080
1081 QNEEYVKKNALLNERYNKLLNIFSYFKGKHNLINDSNEKNIPNNMKREQLNIINSMLYNE 1140
1141 IYEQNLMGNKIDINYGSSSIVKDKKEMSDNNNITEFKEHKNLTKIGNKTRDDVIDILICG 1200
1201 PKGVGKTSLMEDLFVRLGDENNLNILRKKNKKKEIGNINHPNYNTYIVNHKLSQIKIVDC 1260
1261 GYSDNTSSEEILFEYIKNSICIIIVFDSTNKESIIPALHLLQEASLINVKKSTKLYLLEN 1320
1321 IFNEKINLNPNVNDVSYAQKVSKTCNATYIRALDIYDILNDYVNRITTNSTYFLNNFISE 1380
1381 ETISKNMFINSKHFHTHDSSNNDNNIIEHLDRSNSRWFQNENRYKENIKNGNNCILGKTD 1440
1441 EYFHNFDKFDKFGKFDKIQEGEINLLRHQSSTQSVNNIQDNKDIENKNLIYIKNENDIYR 1500
1501 ESYDKYSTNNLGKKKQIIQLLRESLPHNNYVYNSKKYNTELGKGLQPVYEIMIKDNTPIT 1560
1561 YLCIGQNSINKNYTILAVGCKDGIIYIYKCFRTKMEQSDTFQTRGQENETINNSNHEKEL 1620
1621 VRNRKKGNLSNEEVNNSELSNPEEEEEDENNTIEYINETIKDESSFTLSEDNSMSTVLLS 1680
1681 KLLGHRKAITCLVFSFSEDKIISSSIDRTIKIWEVSTGFLLKVFSDSSATLSVLLFPTNL 1740
1741 DIFLCSNCTSLLRMVNLNSGQVYQKIKVESEIRALEMDYTCLNIFAGSKNGTIYLLECLY 1800
1801 NERVEIKFRFLFSLLPITCIKFVPRKYIHTPPTIIVNSCDNHIGIIECVYGNKGIITNLS 1860
1861 VKHRIRINHALLPIRSCYTKFGGGWLVSGSEDGNIYVCSLLPQSNYKLILLKHHKAPVMS 1920
1921 VVVNDIDTLMVSGDSKGNIVFWRRSLI 1947

Alignement of domain consensus (first line) on the sequence (colored line).

Each position reports the amino acid with highest probability; capital letters mean highly conserved residues (i.e. with probability > 50%).

Occurence 1546...1589 
   1 geck.vl.gHtstVtcvafspd....sgpllasgSrDgtikiWd   44
1546 QPVYeIMiKDNTPITYLCIGQNsinkNYTILAVGCKDGIIYIYK 1589
Occurence 1804...1847 
   1 geck.vl.gHtstVtcvafspd....sgpllasgSrDgtikiWd   44
1804 VEIKfRFlFSLLPITCIKFVPRkyihTPPTIIVNSCDNHIGIIE 1847
Occurence 1861...1899 
   1 geck.vl.gHtstVtcvafspdgpllasgSrDgtikiWd   39
1861 VKHRiRInHALLPIRSCYTKFGGGWLVSGSEDGNIYVCS 1899
Occurence 1905...1943 
   1 geck.vl.gHtstVtcvafspdgpllasgSrDgtikiWd   39
1905 NYKLiLLkHHKAPVMSVVVNDIDTLMVSGDSKGNIVFWR 1943